Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3. (Q33372690)

26 July 2017

Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3. (English)

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26 July 2017

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8

Kenneth C Anderson

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26 July 2017

6

Hiroshi Ikeda

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26 July 2017

Erik A Nelson

1

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26 July 2017

Sarah R Walker

2

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26 July 2017

Alicia Kepich

3

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26 July 2017

Laurie B Gashin

4

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26 July 2017

Teru Hideshima

5

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26 July 2017

Dharminder Chauhan

7

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26 July 2017

David A Frank

9

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26 July 2017

language of work or name

English

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publication date

29 September 2008

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26 July 2017

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112

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5095-5102

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13

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describes a project that uses

26 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2597607/fullTextXML

inferred from PubMed Central ID database lookup

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A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells

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STAT3 as a central mediator of neoplastic cellular transformation

28 July 2018

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Pyridone 6, a pan-Janus-activated kinase inhibitor, induces growth inhibition of multiple myeloma cells

28 July 2018

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Identification of human STAT5-dependent gene regulatory elements based on interspecies homology

28 July 2018

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STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas

28 July 2018

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The role of the bone microenvironment in the pathophysiology and therapeutic management of multiple myeloma: interplay of growth factors, their receptors and stromal interactions

28 July 2018

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Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor

28 July 2018

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Isolation of unique STAT5 targets by chromatin immunoprecipitation-based gene identification

28 July 2018

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Mcl-1 regulation and its role in multiple myeloma

28 July 2018

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A review of depsipeptide and other histone deacetylase inhibitors in clinical trials

28 July 2018

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Jak family of kinases in cancer

28 July 2018

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Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma

28 July 2018

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Expression of IL-6 and IL-6 receptors by circulating clonotypic B cells in multiple myeloma: potential for autocrine and paracrine networks.

28 July 2018

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28 July 2018

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

28 July 2018

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Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2597607

B lymphocytes from patients with chronic lymphocytic leukemia contain signal transducer and activator of transcription (STAT) 1 and STAT3 constitutively phosphorylated on serine residues.

28 July 2018

1 reference

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Adhesion of human myeloma-derived cell lines to bone marrow stromal cells stimulates interleukin-6 secretion

28 July 2018

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Requirement of serine phosphorylation for formation of STAT-promoter complexes

28 July 2018

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Double-blind controlled study of the efficacy of nifuroxazide versus placebo in the treatment of acute diarrhea in adults

28 July 2018

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The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter

28 July 2018

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28 July 2018

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Mechanisms of disease: Insights into the emerging role of signal transducers and activators of transcription in cancer

31 October 2018

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Combined disruption of both the MEK/ERK and the IL-6R/STAT3 pathways is required to induce apoptosis of multiple myeloma cells in the presence of bone marrow stromal cells

31 October 2018

1 reference

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Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-FLIP protein

31 October 2018

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Histone deacetylase inhibitors in cancer treatment

31 October 2018

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Histone deacetylase inhibitors: a new class of potential therapeutic agents for cancer treatment.

31 October 2018

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A new class of nifuroxazide analogues: synthesis of 5-nitrothiophene derivatives with antimicrobial activity against multidrug-resistant Staphylococcus aureus

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18824601

12 December 2020

inferred from PubMed ID database lookup

Inhibition of constitutively activated Stat3 signaling pathway suppresses growth of prostate cancer cells

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PubMed

https://pubmed.ncbi.nlm.nih.gov/18824601

12 December 2020

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Synthesis and biological activity of nifuroxazide and analogs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18824601

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1182/BLOOD-2007-12-129718

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26 July 2017

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26 July 2017

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