Junín virus infection of human hematopoietic progenitors impairs in vitro proplatelet formation and platelet release via a bystander effect involving type I IFN signaling. (Q33389296)

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English	Junín virus infection of human hematopoietic progenitors impairs in vitro proplatelet formation and platelet release via a bystander effect involving type I IFN signaling.	scientific article

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1 February 2020

Junín virus infection of human hematopoietic progenitors impairs in vitro proplatelet formation and platelet release via a bystander effect involving type I IFN signaling (English)

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1 February 2020

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Junín virus

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Víctor Romanowski

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Carolina Jaquenod de Giusti

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Carolina Jaquenod de Giusti

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Mirta Schattner

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Mirta Schattner

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Joseph E. Italiano

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Joseph E Italiano

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Roberto G Pozner

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Lina P D'Atri

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Oscar Torres

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Ricardo M Gómez

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15 April 2010

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6

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4

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e1000847

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1 February 2020

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Creative Commons Attribution 4.0 International

15 April 2010

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Interferon-alpha 2b-induced thrombocytopenia is caused by inhibition of platelet production but not proliferation and endomitosis in human megakaryocytes

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Dengue 2 virus inhibits in vitro megakaryocytic colony formation and induces apoptosis in thrombopoietin-inducible megakaryocytic differentiation from cord blood CD34+ cells

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Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus.

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From hematopoietic stem cells to platelets.

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Thrombocytopenia in HIV infection: impairment of platelet formation and loss correlates with increased c-Mpl and ligand thrombopoietin expression

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Junin Virus Infection of Callithrix Jacchus: Pathologic Features *

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Interaction of human herpesvirus 6 with human CD34 positive cells

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Markedly elevated levels of interferon (IFN)-gamma, IFN-alpha, interleukin (IL)-2, IL-10, and tumor necrosis factor-alpha associated with fatal Ebola virus infection

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Adhesive receptors, extracellular proteins and myosin IIA orchestrate proplatelet formation by human megakaryocytes.

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Effects of cytokines on platelet production from blood and marrow CD34+ cells

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Activation of cyclic AMP pathway prevents CD34(+) cell apoptosis

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10.1371/JOURNAL.PPAT.1000847

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