The extended substrate specificity of the human mast cell chymase reveals a serine protease with well-defined substrate recognition profile (Q33392156)

26 July 2017

The extended substrate specificity of the human mast cell chymase reveals a serine protease with well-defined substrate recognition profile (English)

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26 July 2017

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Mattias K Andersson

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26 July 2017

Mattias Enoksson

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2

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26 July 2017

Maike Gallwitz

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3

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26 July 2017

Lars Hellman

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4

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26 July 2017

10 December 2008

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26 July 2017

International Immunology

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26 July 2017

21

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26 July 2017

95-104

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26 July 2017

1

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Two types of human mast cells that have distinct neutral protease compositions

26 July 2017

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

The human mast cell chymase gene (CMA1): mapping to the cathepsin G/granzyme gene cluster and lineage-restricted expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Extended substrate specificity of opossum chymase--implications for the origin of mast cell chymases

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Expansion of the mast cell chymase locus over the past 200 million years of mammalian evolution

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Angiotensin II generation by mast cell alpha- and beta-chymases

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Rapid lineage-specific diversification of the mast cell chymase locus during mammalian evolution

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Species differences in angiotensin II generation and degradation by mast cell chymases

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Enzyme-histochemical detection of a chymase-like proteinase within bovine mucosal and connective tissue mast cells.

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Evidence for diversity of substrate specificity among members of the chymase family of serine proteases

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Rodent alpha-chymases are elastase-like proteases

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Extended substrate specificity of rat mast cell protease 5, a rodent alpha-chymase with elastase-like primary specificity

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Structural basis for elastolytic substrate specificity in rodent alpha-chymases

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Guinea pig chymase is leucine-specific: a novel example of functional plasticity in the chymase/granzyme family of serine peptidases

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

New developments in the genetics and activation of mast cell proteases

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Biochemical and immunological characterization of multiple glycoforms of mouse mast cell protease 1: comparison with an isolated murine serosal mast cell protease (MMCP-4).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Rat mast cell protease 4 is a beta-chymase with unusually stringent substrate recognition profile

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Demonstration of chymotryptic and tryptic activities in mast cells of rodents: comparison of 17 species of the family Muridae

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

The chymase, mouse mast cell protease 4, constitutes the major chymotrypsin-like activity in peritoneum and ear tissue. A role for mouse mast cell protease 4 in thrombin regulation and fibronectin turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

The extended cleavage specificity of the rodent beta-chymases rMCP-1 and mMCP-4 reveal major functional similarities to the human mast cell chymase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Mast cells promote homeostasis by limiting endothelin-1-induced toxicity.

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Chymase cleavage of stem cell factor yields a bioactive, soluble product

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Dog mast cell alpha-chymase activates progelatinase B by cleaving the Phe88-Gln89 and Phe91-Glu92 bonds of the catalytic domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Human chymase degrades human fibronectin

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Cleavage of type I procollagen by human mast cell chymase initiates collagen fibril formation and generates a unique carboxyl-terminal propeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Albumin is a substrate of human chymase. Prediction by combinatorial peptide screening and development of a selective inhibitor based on the albumin cleavage site

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Inhibitors of human heart chymase based on a peptide library

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Generation of therapeutic antibody responses against IgE through vaccination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

On the size of the active site in proteases. I. Papain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Comparative modeling methods: application to the family of the mammalian serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

The 2.2 A crystal structure of human chymase in complex with succinyl-Ala-Ala-Pro-Phe-chloromethylketone: structural explanation for its dipeptidyl carboxypeptidase specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Extended cleavage specificity of mMCP-1, the major mucosal mast cell protease in mouse-high specificity indicates high substrate selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Lys40 but not Arg143 influences selectivity of angiotensin conversion by human alpha-chymase

21 January 2018

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https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Three-dimensional molecular modeling explains why catalytic function for angiotensin-I is different between human and rat chymases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Structural characterization of the cell wall binding domains of Clostridium difficile toxins A and B; evidence that Ca2+ plays a role in toxin A cell surface association.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Identification and characterization of conserved and variable regions in the neutralization VP2 gene of bluetongue virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

Two feeding-induced proteins from the male gonad trigger engorgement of the female tick Amblyomma hebraeum

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FINTIMM%2FDXN128

21 January 2018

Identifiers

DOI

10.1093/INTIMM/DXN128

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26 July 2017

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