A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours (Q33394173)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

title

A phase I study of the safety and tolerability of olaparib (AZD2281, KU0059436) and dacarbazine in patients with advanced solid tumours (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Alastair Peter Greystoke

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Raffaele Califano

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

author name string

O A Khan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

M Gore

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

J Stone

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

W Burke

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

J Carmichael

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

A J Watson

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

G McGown

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

M Thorncroft

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

G P Margison

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

J Larkin

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

S Wellman

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

M R Middleton

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

language of work or name

English

0 references

publication date

15 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Cancer

22 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

volume

104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

page(s)

750-755

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

22 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048218

O(6)-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048218

The potential role and application of PARP inhibitors in cancer treatment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048218

Phase I study of the poly(ADP-ribose) polymerase inhibitor, AG014699, in combination with temozolomide in patients with advanced solid tumors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048218

4-[3-(4-cyclopropanecarbonylpiperazine-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one: a novel bioavailable inhibitor of poly(ADP-ribose) polymerase-1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048218

Temozolomide for the treatment of metastatic melanoma: a systematic review

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048218

DNA glycosylase recognition and catalysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048218

Palliative therapy of disseminated malignant melanoma: a systematic review of 41 randomised clinical trials.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048218

The therapeutic potential of poly(ADP-ribose) polymerase inhibitors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048218

Effects of single or split exposure of leukemic cells to temozolomide, combined with poly(ADP-ribose) polymerase inhibitors on cell growth, chromosomal aberrations and base excision repair components.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048218

Randomized phase III study of temozolomide versus dacarbazine in the treatment of patients with advanced metastatic malignant melanoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048218

Involvement of poly(ADP-ribose) polymerase in base excision repair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048218

Development and application of a sensitive and rapid immunoassay for the quantitation of N7-methyldeoxyguanosine in DNA samples

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FBJC.2011.8

Response evaluation criteria in solid tumors (RECIST): new guidelines

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21326243

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multicenter randomized trial of dacarbazine alone or in combination with two different doses and schedules of interferon alfa-2a in the treatment of advanced melanoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21326243

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Treatment with temozolomide and poly(ADP-ribose) polymerase inhibitors induces early apoptosis and increases base excision repair gene transcripts in leukemic cells resistant to triazene compounds

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21326243

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/BJC.2011.8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

22 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21326243%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

21326243

1 reference