Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue (Q33398170)

26 July 2017

title

Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue (English)

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26 July 2017

Patrick Chène

1

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26 July 2017

Joëlle Rudloff

2

1 reference

26 July 2017

Joseph Schoepfer

3

1 reference

26 July 2017

Pascal Furet

4

1 reference

26 July 2017

Peter Meier

5

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26 July 2017

Zhiyan Qian

6

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26 July 2017

Jean-Marc Schlaeppi

7

1 reference

26 July 2017

Rita Schmitz

8

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26 July 2017

Thomas Radimerski

9

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26 July 2017

publication date

7 January 2009

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26 July 2017

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26 July 2017

volume

9

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26 July 2017

page(s)

1

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Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation

26 July 2017

cites work

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21 June 2018

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C-terminal regions of topoisomerase IIalpha and IIbeta determine isoform-specific functioning of the enzymes in vivo

21 June 2018

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The decatenation checkpoint

21 June 2018

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A three-dimensional quantitative structure-activity relationship study of the inhibition of the ATPase activity and the strand passing catalytic activity of topoisomerase IIalpha by substituted purine analogs.

21 June 2018

1 reference

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A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin.

21 June 2018

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Coordinated requirements of human topo II and cohesin for metaphase centromere alignment under Mad2-dependent spindle checkpoint surveillance

21 June 2018

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Decatenation checkpoint deficiency in stem and progenitor cells

21 June 2018

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Recent advances in understanding structure–function relationships in the type II topoisomerase mechanism

21 June 2018

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The histone code at DNA breaks: a guide to repair?

21 June 2018

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Substituted purine analogues define a novel structural class of catalytic topoisomerase II inhibitors

21 June 2018

1 reference

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BRCA1 participates in DNA decatenation

21 June 2018

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Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells

21 June 2018

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A cell-based immunocytochemical assay for monitoring kinase signaling pathways and drug efficacy

21 June 2018

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Construction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell line

21 June 2018

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Inhibition of DNA decatenation, but not DNA damage, arrests cells at metaphase

21 June 2018

1 reference

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Topoisomerase II and histone deacetylase inhibitors delay the G2/M transition by triggering the p38 MAPK checkpoint pathway

21 June 2018

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Chromosomal aberrations and genomic instability induced by topoisomerase-targeted antitumour drugs

21 June 2018

1 reference

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AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity

21 June 2018

1 reference

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Identification of decatenation G2 checkpoint impairment independently of DNA damage G2 checkpoint in human lung cancer cell lines.

21 June 2018

1 reference

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DNA strand breaks induced by the anti-topoisomerase II bis-dioxopiperazine ICRF-193.

21 June 2018

1 reference

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Structure of the topoisomerase II ATPase region and its mechanism of inhibition by the chemotherapeutic agent ICRF-187

21 June 2018

1 reference

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Catalytic topoisomerase II inhibitors in cancer therapy.

21 June 2018

1 reference

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Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628638

Characterisation of the DNA-dependent ATPase activity of human DNA topoisomerase IIbeta: mutation of Ser165 in the ATPase domain reduces the ATPase activity and abolishes the in vivo complementation ability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628638

A human topoisomerase II alpha heterodimer with only one ATP binding site can go through successive catalytic cycles.

21 June 2018

1 reference

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Cellular roles of dna topoisomerases: a molecular perspective

21 June 2018

1 reference

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The human decatenation checkpoint.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628638

DNA topoisomerase IIbeta and neural development

21 June 2018

1 reference

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Chinese hamster ovary cells resistant to the topoisomerase II catalytic inhibitor ICRF-159: a Tyr49Phe mutation confers high-level resistance to bisdioxopiperazines.

21 June 2018

1 reference

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The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X-ray crystallography

21 June 2018

1 reference

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A topoisomerase II-dependent G2 cycle checkpoint in mammalian cells/.

21 June 2018

1 reference

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628638

DNA topoisomerase II must act at mitosis to prevent nondisjunction and chromosome breakage.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628638

Qualitative and quantitative aspects of intercalator-induced DNA strand breaks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628638

An improved assay for nanomole amounts of inorganic phosphate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628638

Cell cycle-dependent DNA damage signaling induced by ICRF-193 involves ATM, ATR, CHK2, and BRCA1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628638

Nucleotide-dependent domain movement in the ATPase domain of a human type IIA DNA topoisomerase.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628638

Functional compatibility between isoform alpha and beta of type II DNA topoisomerase

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628638

The G2-phase decatenation checkpoint is defective in Werner syndrome cells

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628638

Topoisomerase II poisoning by ICRF-193.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2628638

Clinical applications of anticancer drugs targeted to topoisomerase II

31 October 2018

1 reference

12 December 2020

Adriamycin-induced DNA damage mediated by mammalian DNA topoisomerase II

1 reference

12 December 2020

DNA topoisomerase II is required for condensation and separation of mitotic chromosomes in S. pombe

1 reference

12 December 2020

Differential sensitivities of recombinant human topoisomerase IIalpha and beta to various classes of topoisomerase II-interacting agents

1 reference

12 December 2020

Identifiers

DOI

10.1186/1472-6769-9-1

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Dimensions Publication ID

26 July 2017

0 references

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26 July 2017

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