Hypoxia induces permeability and giant cell responses of Andes virus-infected pulmonary endothelial cells by activating the mTOR-S6K signaling pathway (Q33410566)

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English	Hypoxia induces permeability and giant cell responses of Andes virus-infected pulmonary endothelial cells by activating the mTOR-S6K signaling pathway	scientific article

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scholarly article

1 reference

Europe PubMed Central

26 July 2017

Hypoxia induces permeability and giant cell responses of Andes virus-infected pulmonary endothelial cells by activating the mTOR-S6K signaling pathway (English)

1 reference

Europe PubMed Central

26 July 2017

0 references

author name string

Irina N Gavrilovskaya

1

1 reference

Europe PubMed Central

26 July 2017

Elena E Gorbunova

2

1 reference

Europe PubMed Central

26 July 2017

Erich R Mackow

3

1 reference

Europe PubMed Central

26 July 2017

publication date

25 September 2013

1 reference

Europe PubMed Central

26 July 2017

Journal of Virology

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Europe PubMed Central

26 July 2017

87

1 reference

Europe PubMed Central

26 July 2017

12999-13008

1 reference

Europe PubMed Central

26 July 2017

23

1 reference

Europe PubMed Central

26 July 2017

Uncovering the mysteries of hantavirus infections

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21 June 2018

Endothelial cell permeability during hantavirus infection involves factor XII-dependent increased activation of the kallikrein-kinin system

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21 June 2018

Slit2-Robo4 receptor responses inhibit ANDV directed permeability of human lung microvascular endothelial cells

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21 June 2018

The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability

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21 June 2018

Elevated VEGF Levels in Pulmonary Edema Fluid and PBMCs from Patients with Acute Hantavirus Pulmonary Syndrome

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21 June 2018

The Role of the Endothelium in HPS Pathogenesis and Potential Therapeutic Approaches

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21 June 2018

The Syrian hamster model of hantavirus pulmonary syndrome

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21 June 2018

Andes virus infection of lymphatic endothelial cells causes giant cell and enhanced permeability responses that are rapamycin and vascular endothelial growth factor C sensitive

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21 June 2018

mTOR signaling in growth control and disease

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21 June 2018

The lymphatic vasculature in disease

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21 June 2018

T cells are not required for pathogenesis in the Syrian hamster model of hantavirus pulmonary syndrome.

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21 June 2018

Regulation of mammalian target of rapamycin complex 1 (mTORC1) by hypoxia: causes and consequences

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21 June 2018

Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia

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21 June 2018

Increased Akt-mTOR signaling in lung epithelium is associated with respiratory distress syndrome in mice

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21 June 2018

VEGFR2 and Src kinase inhibitors suppress Andes virus-induced endothelial cell permeability

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21 June 2018

Andes virus regulation of cellular microRNAs contributes to hantavirus-induced endothelial cell permeability

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21 June 2018

Andes virus disrupts the endothelial cell barrier by induction of vascular endothelial growth factor and downregulation of VE-cadherin

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21 June 2018

Pathogenic hantaviruses Andes virus and Hantaan virus induce adherens junction disassembly by directing vascular endothelial cadherin internalization in human endothelial cells

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21 June 2018

New insights in the pathogenesis of high-altitude pulmonary edema

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21 June 2018

Pathogenic hantaviruses direct the adherence of quiescent platelets to infected endothelial cells

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21 June 2018

Rapamycin inhibits VEGF-induced microvascular hyperpermeability in vivo

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21 June 2018

VEGF-mediated signal transduction in lymphatic endothelial cells

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21 June 2018

Hypoxia-induced expression of bradykinin type-2 receptors in endothelial cells triggers NO production, cell migration, and angiogenesis

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21 June 2018

Rapamycin inhibition of the Akt/mTOR pathway blocks select stages of VEGF-A164-driven angiogenesis, in part by blocking S6Kinase

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21 June 2018

Many roads to maturity: microRNA biogenesis pathways and their regulation

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21 June 2018

Breaking the VE-cadherin bonds.

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21 June 2018

Storage of cellular 5' mRNA caps in P bodies for viral cap-snatching

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The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend

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21 June 2018

Amicus or adversary: platelets in lung biology, acute injury, and inflammation

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21 June 2018

The role of adherens junctions and VE-cadherin in the control of vascular permeability

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21 June 2018

Hantaviruses direct endothelial cell permeability by sensitizing cells to the vascular permeability factor VEGF, while angiopoietin 1 and sphingosine 1-phosphate inhibit hantavirus-directed permeability

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21 June 2018

A microRNA component of the hypoxic response

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21 June 2018

Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif

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21 June 2018

Temporal analysis of Andes virus and Sin Nombre virus infections of Syrian hamsters

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21 June 2018

Hantavirus cardiopulmonary syndrome

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21 June 2018

Hypoxia alters the adhesive properties of lymphatic endothelial cells. A transcriptional and functional study

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21 June 2018

A novel role of hypoxia-inducible factor in cobalt chloride- and hypoxia-mediated expression of IL-8 chemokine in human endothelial cells

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21 June 2018

VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin

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21 June 2018

Increased permeability of human endothelial cell line EA.hy926 induced by hantavirus-specific cytotoxic T lymphocytes

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The pathogenic NY-1 hantavirus G1 cytoplasmic tail inhibits RIG-I- and TBK-1-directed interferon responses

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Vascular endothelial cadherin controls VEGFR-2 internalization and signaling from intracellular compartments

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Reactive oxygen species regulate insulin-induced VEGF and HIF-1alpha expression through the activation of p70S6K1 in human prostate cancer cells

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Ribosomal protein S6 phosphorylation: from protein synthesis to cell size.

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Mechanisms of pulmonary edema clearance

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Pathogenesis of high altitude pulmonary edema: does alveolar epithelial lining fluid vascular endothelial growth factor exacerbate capillary leak?

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Pathogenic hantaviruses bind plexin-semaphorin-integrin domains present at the apex of inactive, bent alphavbeta3 integrin conformers

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Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

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Dysregulation of HIF and VEGF is a unifying feature of the familial hamartoma syndromes

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Loss of Tsc1 or Tsc2 induces vascular endothelial growth factor production through mammalian target of rapamycin

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Hypoxia upregulates VEGF expression in alveolar epithelial cells in vitro and in vivo

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Pathogenic and nonpathogenic hantaviruses differentially regulate endothelial cell responses

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Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

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Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling

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A lethal disease model for hantavirus pulmonary syndrome

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Hantavirus infection induces the expression of RANTES and IP-10 without causing increased permeability in human lung microvascular endothelial cells

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Permeability of endothelial monolayers to albumin is increased by bradykinin and inhibited by prostaglandins

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VEGF transiently disrupts gap junctional communication in endothelial cells

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Vascular endothelial growth factor-induced prostacyclin production is mediated by a protein kinase C (PKC)-dependent activation of extracellular signal-regulated protein kinases 1 and 2 involving PKC-delta and by mobilization of intracellular Ca2+

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Platelet-derived growth factor receptor beta and vascular endothelial growth factor receptor 2 bind to the beta 3 integrin through its extracellular domain

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21 June 2018

Cellular entry of hantaviruses which cause hemorrhagic fever with renal syndrome is mediated by beta3 integrins.

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21 June 2018

Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.

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beta3 Integrins mediate the cellular entry of hantaviruses that cause respiratory failure

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Hantavirus regulation of endothelial cell functions.

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31 October 2018

Angiopoietin-1 prevents VEGF-induced endothelial permeability by sequestering Src through mDia.

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31 October 2018

Dominant-negative Hsp90 reduces VEGF-stimulated nitric oxide release and migration in endothelial cells

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31 October 2018

Hypoxia causes permeability oedema in the constant-pressure perfused rat lung

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31 October 2018

Hypoxia impairs systemic endothelial function in individuals prone to high-altitude pulmonary edema

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838155

31 October 2018

Endothelial nitric oxide synthase regulates microlymphatic flow via collecting lymphatics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838155

31 October 2018

Transactivation of KDR/Flk-1 by the B2 receptor induces tube formation in human coronary endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838155

31 October 2018

Pulmonary lymphatics and edema accumulation after brief lung injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838155

31 October 2018

Vascular endothelial growth factor in patients with high-altitude pulmonary edema

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838155

31 October 2018

High-altitude pulmonary edema

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838155

31 October 2018

Rapid transactivation of the vascular endothelial growth factor receptor KDR/Flk-1 by the bradykinin B2 receptor contributes to endothelial nitric-oxide synthase activation in cardiac capillary endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838155

31 October 2018

Human airway smooth muscle cells secrete vascular endothelial growth factor: up-regulation by bradykinin via a protein kinase C and prostanoid-dependent mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838155

31 October 2018

Lung overexpression of the vascular endothelial growth factor gene induces pulmonary edema.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838155

31 October 2018

Increased vascular endothelial growth factor production in the lungs of rats with hypoxia-induced pulmonary hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838155

31 October 2018

Ultrastructural characteristics of Sin Nombre virus, causative agent of hantavirus pulmonary syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3838155

31 October 2018

Kallikrein stimulates prostacyclin production in bovine vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/24067973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of hypoxia on capillary endothelial cell function: modulation of barrier and coagulant function

1 reference

https://pubmed.ncbi.nlm.nih.gov/24067973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta3-integrin regulates vascular endothelial growth factor-A-dependent permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/24067973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mechanism for modulation of cellular responses to VEGF: activation of the integrins

1 reference

https://pubmed.ncbi.nlm.nih.gov/24067973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hantavirus pulmonary syndrome in Argentina. Possibility of person to person transmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/24067973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins

1 reference

https://pubmed.ncbi.nlm.nih.gov/24067973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiopulmonary manifestations of hantavirus pulmonary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/24067973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pleural fluid characteristics in hantavirus pulmonary syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/24067973

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.02103-13

1 reference

Europe PubMed Central

26 July 2017

1 reference

Europe PubMed Central

26 July 2017

1 reference

Europe PubMed Central

26 July 2017

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