Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome (Q33415311)

26 July 2017

Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasome (English)

1 reference

26 July 2017

1 reference

Sivapriya Kailasan Vanaja

1

1 reference

26 July 2017

Vijay A K Rathinam

2

1 reference

26 July 2017

Maninjay K Atianand

3

1 reference

26 July 2017

Parisa Kalantari

4

1 reference

26 July 2017

Brian Skehan

5

1 reference

26 July 2017

Katherine A Fitzgerald

6

1 reference

26 July 2017

John M Leong

7

1 reference

26 July 2017

language of work or name

English

0 references

publication date

14 May 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

26 July 2017

1 reference

26 July 2017

111

1 reference

26 July 2017

7765-7770

1 reference

26 July 2017

21

1 reference

RNA:DNA hybrids are a novel molecular pattern sensed by TLR9.

26 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

The DHX33 RNA helicase senses cytosolic RNA and activates the NLRP3 inflammasome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

The sub-nanomolar binding of DNA-RNA hybrids by the single-chain Fv fragment of antibody S9.6.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

The protein kinase PKR is critical for LPS-induced iNOS production but dispensable for inflammasome activation in macrophages

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Premature activation of the HIV RNase H drives the virus into suicide: a novel microbicide?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

TRIF licenses caspase-11-dependent NLRP3 inflammasome activation by gram-negative bacteria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Novel role of PKR in inflammasome activation and HMGB1 release

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

R loops: from transcription byproducts to threats to genome stability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Regulation of inflammasome signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Detection of prokaryotic mRNA signifies microbial viability and promotes immunity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

The caspase-1 inflammasome: a pilot of innate immune responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

A murine model of HUS: Shiga toxin with lipopolysaccharide mimics the renal damage and physiologic response of human disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Acute inflammation in the pathogenesis of hemolytic-uremic syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Structural biochemistry of a type 2 RNase H: RNA primer recognition and removal during DNA replication

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Genome sequence of enterohaemorrhagic Escherichia coli O157:H7

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Pretreatment of mice with lipopolysaccharide (LPS) or IL-1beta exerts dose-dependent opposite effects on Shiga toxin-2 lethality

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Mode of initiation of constitutive stable DNA replication in RNase H-defective mutants of Escherichia coli K-12.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

RNase H-defective mutants of Escherichia coli

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

RNA:DNA hybrids are more stable than DNA:DNA duplexes in concentrated perchlorate and trichloroacetate solutions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4040571

Molecular mechanisms of Escherichia coli pathogenicity

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400075111

Enterohemolysin operon of Shiga toxin-producing Escherichia coli: a virulence function of inflammatory cytokine production from human monocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400075111

Transcriptional activation of initiation of replication from the E. coli chromosomal origin: an RNA-DNA hybrid near oriC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400075111

Molecular recognition of a DNA:RNA hybrid: sub-nanomolar binding by a neomycin-methidium conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1400075111

A mechanism of formation of a persistent hybrid between elongating RNA and template DNA

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24828532

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1400075111

1 reference

26 July 2017

0 references

1 reference

26 July 2017

1 reference