A phase I/II trial of belinostat in combination with cisplatin, doxorubicin, and cyclophosphamide in thymic epithelial tumors: a clinical and translational study. (Q33417499)

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English	A phase I/II trial of belinostat in combination with cisplatin, doxorubicin, and cyclophosphamide in thymic epithelial tumors: a clinical and translational study.	scientific article

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16 February 2020

A phase I/II trial of belinostat in combination with cisplatin, doxorubicin, and cyclophosphamide in thymic epithelial tumors: a clinical and translational study (English)

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16 February 2020

phase I clinical trial

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phase II clinical trial

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ChEBI release 2020-05-28

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based on heuristic

inferred from title

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1

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16 February 2020

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16 February 2020

Giuseppe Giaccone

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16 February 2020

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Jane B Trepel

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16 February 2020

William Douglas Figg, Sr.

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William D Figg

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16 February 2020

Seth M Steinberg

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Seth M Steinberg

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16 February 2020

Richard L Piekarz

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Richard Piekarz

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Corey A. Carter

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Corey A Carter

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16 February 2020

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Arun Rajan

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16 February 2020

Yusuke Tomita

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Barbara Scepura

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16 February 2020

Ariel Lopez-Chavez

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16 February 2020

Min-Jung Lee

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16 February 2020

Christophe E Redon

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Ari Frosch

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16 February 2020

Cody J Peer

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16 February 2020

Yuanbin Chen

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16 February 2020

David S Schrump

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4 September 2014

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16 February 2020

Clinical Cancer Research

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16 February 2020

5392-5402

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16 February 2020

EGFR-TKI resistance due to BIM polymorphism can be circumvented in combination with HDAC inhibition.

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21 June 2018

Characterization and management of cardiac involvement of thymic epithelial tumors

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21 June 2018

Epigenetic therapy using belinostat for patients with unresectable hepatocellular carcinoma: a multicenter phase I/II study with biomarker and pharmacokinetic analysis of tumors from patients in the Mayo Phase II Consortium and the Cancer Therapeuti

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21 June 2018

HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications

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21 June 2018

Thymic malignancies: from clinical management to targeted therapies

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21 June 2018

Belinostat: clinical applications in solid tumors and lymphoma

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21 June 2018

Phase II study of the histone deacetylase inhibitor belinostat (PXD101) for the treatment of myelodysplastic syndrome (MDS).

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21 June 2018

Phase II study of belinostat in patients with recurrent or refractory advanced thymic epithelial tumors

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Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

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Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients

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21 June 2018

Pharmacokinetic and pharmacodynamic properties of an oral formulation of the histone deacetylase inhibitor Belinostat (PXD101).

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21 June 2018

A phase I study of the safety and pharmacokinetics of the histone deacetylase inhibitor belinostat administered in combination with carboplatin and/or paclitaxel in patients with solid tumours

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New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

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21 June 2018

Gamma-H2AX - a novel biomarker for DNA double-strand breaks.

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HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells

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21 June 2018

Immune-potentiating effects of the chemotherapeutic drug cyclophosphamide

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21 June 2018

Histologic classification of thymoma: the World Health Organization and beyond

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21 June 2018

Enhancement of radiation sensitivity of human squamous carcinoma cells by histone deacetylase inhibitors

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21 June 2018

Phase II study of a multidisciplinary approach with induction chemotherapy, followed by surgical resection, radiation therapy, and consolidation chemotherapy for unresectable malignant thymomas: final report

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21 June 2018

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21 June 2018

Cisplatin plus doxorubicin plus cyclophosphamide in metastatic or recurrent thymoma: final results of an intergroup trial. The Eastern Cooperative Oncology Group, Southwest Oncology Group, and Southeastern Cancer Study Group

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21 June 2018

Follow-up study of thymomas with special reference to their clinical stages

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21 June 2018

A phase 1 pharmacokinetic and pharmacodynamic study of the histone deacetylase inhibitor belinostat in patients with advanced solid tumors

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31 October 2018

Deacetylase inhibition promotes the generation and function of regulatory T cells.

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Long-term disease-free survival of patients with radically resected thymomas: relevance of cell-cycle protein expression.

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31 October 2018

Malignant thymoma in the United States: demographic patterns in incidence and associations with subsequent malignancies.

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31 October 2018

New WHO histologic classification predicts prognosis of thymic epithelial tumors: a clinicopathologic study of 200 thymoma cases from China

1 reference

https://pubmed.ncbi.nlm.nih.gov/25189481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemotherapy of invasive thymoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25189481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective loss of regulatory T cells in thymomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/25189481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Managements of locally advanced unresectable thymic epithelial tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25189481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lymphogenous and hematogenous metastasis of thymic epithelial tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/25189481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multidisciplinary treatment for advanced invasive thymoma with cisplatin, doxorubicin, and methylprednisolone

1 reference

https://pubmed.ncbi.nlm.nih.gov/25189481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The conflicting roles of the cdk inhibitor p21(CIP1/WAF1) in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25189481

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-14-0968

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16 February 2020

1 reference

Europe PubMed Central

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16 February 2020

1 reference

Europe PubMed Central

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16 February 2020

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