DPYD variants as predictors of 5-fluorouracil toxicity in adjuvant colon cancer treatment (NCCTG N0147). (Q33418614)

26 July 2017

title

DPYD variants as predictors of 5-fluorouracil toxicity in adjuvant colon cancer treatment (NCCTG N0147). (English)

1 reference

26 July 2017

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1 reference

4

Steven R Alberts

1 reference

26 July 2017

Adam M Lee

1

1 reference

26 July 2017

Qian Shi

2

1 reference

26 July 2017

Emily Pavey

3

1 reference

26 July 2017

Daniel J Sargent

5

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26 July 2017

Frank A Sinicrope

6

1 reference

26 July 2017

Jeffrey L Berenberg

7

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26 July 2017

Richard M Goldberg

8

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26 July 2017

Robert B Diasio

9

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26 July 2017

language of work or name

English

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publication date

7 November 2014

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Journal of the National Cancer Institute

26 July 2017

published in

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26 July 2017

volume

106

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26 July 2017

issue

12

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Comparative functional analysis of DPYD variants of potential clinical relevance to dihydropyrimidine dehydrogenase activity

26 July 2017

cites work

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Phenotypic profiling of DPYD variations relevant to 5-fluorouracil sensitivity using real-time cellular analysis and in vitro measurement of enzyme activity

21 June 2018

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Life-threatening toxicity in a dihydropyrimidine dehydrogenase-deficient patient after treatment with topical 5-fluorouracil.

21 June 2018

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Heterozygosity for a point mutation in an invariant splice donor site of dihydropyrimidine dehydrogenase and severe 5-fluorouracil related toxicity

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Dihydropyrimidine dehydrogenase (DPD) deficiency: identification and expression of missense mutations C29R, R886H and R235W

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21 June 2018

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21 June 2018

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Human polymorphism in drug metabolism: mutation in the dihydropyrimidine dehydrogenase gene results in exon skipping and thymine uracilurea.

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Analysis of the DPYD gene implicated in 5-fluorouracil catabolism in a cohort of Caucasian individuals

21 January 2018

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Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group

21 January 2018

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21 January 2018

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Differences in toxicity between men and women treated with 5-fluorouracil therapy for colorectal carcinoma

21 January 2018

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Denaturing high performance liquid chromatography analysis of the DPYD gene in patients with lethal 5-fluorouracil toxicity.

21 January 2018

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Women experience greater toxicity with fluorouracil-based chemotherapy for colorectal cancer

31 October 2018

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Clinical relevance of different dihydropyrimidine dehydrogenase gene single nucleotide polymorphisms on 5-fluorouracil tolerance

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25381393

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Known variant DPYD alleles do not explain DPD deficiency in cancer patients

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25381393

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Clinical implications of dihydropyrimidine dehydrogenase (DPD) deficiency in patients with severe 5-fluorouracil-associated toxicity: identification of new mutations in the DPD gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25381393

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/JNCI/DJU298

1 reference

26 July 2017

1 reference

26 July 2017

1 reference