Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity (Q33420853)

25733881

26 July 2017

title

Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity (English)

1 reference

Correction for Washburn et al., Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity

26 July 2017

0 references

corrigendum / erratum

0 references

author

Jonathan C Lansing

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

James Meador

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Falk Nimmerjahn

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

author name string

Nathaniel Washburn

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Inessa Schwab

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Daniel Ortiz

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Naveen Bhatnagar

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Amy Medeiros

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Steven Tyler

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Divya Mekala

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Edward Cochran

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Hetal Sarvaiya

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Kevin Garofalo

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Robin Meccariello

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Laura Rutitzky

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Birgit C Schultes

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Leona Ling

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

William Avery

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Anthony M Manning

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Ganesh V Kaundinya

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Carlos J Bosques

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

English

0 references

publication date

2 March 2015

1 reference

25733881

Proceedings of the National Academy of Sciences of the United States of America

26 July 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

E1297-306

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

Synthesis, Processing, and Function of N-glycans in N-glycoproteins

4 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Receptor for AGEs (RAGE) as mediator of NF-kB pathway activation in neuroinflammation and oxidative stress.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Type I and type II Fc receptors regulate innate and adaptive immunity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Treatment response in Kawasaki disease is associated with sialylation levels of endogenous but not therapeutic intravenous immunoglobulin G

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

T cell-independent B cell activation induces immunosuppressive sialylated IgG antibodies.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Challenges and approaches for the development of safer immunomodulatory biologics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Intravenous immunoglobulin therapy: how does IgG modulate the immune system?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

The advantage of specific intravenous immunoglobulin (sIVIG) on regular IVIG: experience of the last decade

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Analysis and functional consequences of increased Fab-sialylation of intravenous immunoglobulin (IVIG) after lectin fractionation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Treatment of immune thrombocytopenia with intravenous immunoglobulin and insights for other diseases. A historical review

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

IVIg-mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Sialylation-independent mechanism involved in the amelioration of murine immune thrombocytopenia using intravenous gammaglobulin.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Advanced glycation end products contribute to the immunogenicity of IFN-β pharmaceuticals.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Intravenous immunoglobulin therapy in rheumatic diseases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Immunoglobulin G galactosylation and sialylation are associated with pregnancy-induced improvement of rheumatoid arthritis and the postpartum flare: results from a large prospective cohort study

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Clinical applications of intravenous immunoglobulins (IVIg)--beyond immunodeficiencies and neurology.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

A close look at human IgG sialylation and subclass distribution after lectin fractionation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Impaired inhibitory Fcgamma receptor IIB expression on B cells in chronic inflammatory demyelinating polyneuropathy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Glycosylation as a strategy to improve antibody-based therapeutics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Identification of a receptor required for the anti-inflammatory activity of IVIG.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Intravenous immunoglobulin: properties, mode of action and practical use in dermatology.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Guidelines on the use of intravenous immune globulin for hematologic conditions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Guidelines on the use of intravenous immune globulin for neurologic conditions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Intravenous immunoglobulin: an update on the clinical use and mechanisms of action.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Differences between IGIV products: impact on clinical outcome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

IVIg-mediated amelioration of murine ITP via FcgammaRIIB is independent of SHIP1, SHP-1, and Btk activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

The multiligand receptor RAGE as a progression factor amplifying immune and inflammatory responses

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Development and characterization of novel erythropoiesis stimulating protein (NESP)

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Anti-inflammatory activity of IVIG mediated through the inhibitory Fc receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Engineered glycoforms of an antineuroblastoma IgG1 with optimized antibody-dependent cellular cytotoxic activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4371931

Glycan profiling of anti-citrullinated protein antibodies isolated from human serum and synovial fluid

28 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1422481112

Intravenous gammaglobulin suppresses inflammation through a novel T(H)2 pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1422481112

IgG Fc N-glycosylation in Guillain-Barré syndrome treated with immunoglobulins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1422481112

Anti-Inflammatory Activity of Immunoglobulin G Resulting from Fc Sialylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1422481112

Broad requirement for terminal sialic acid residues and FcγRIIB for the preventive and therapeutic activity of intravenous immunoglobulins in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1422481112

Therapeutic effect of IVIG on inflammatory arthritis in mice is dependent on the Fc portion and independent of sialylation or basophils.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1422481112

Dendritic cell immunoreceptor: a novel receptor for intravenous immunoglobulin mediates induction of regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1422481112

Phase 1 study results of the type II glycoengineered humanized anti-CD20 monoclonal antibody obinutuzumab (GA101) in B-cell lymphoma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1422481112

Sialylation levels of anti-proteinase 3 antibodies are associated with the activity of granulomatosis with polyangiitis (Wegener's)

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1422481112

Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1422481112

Induction of complement-fixing autoantibodies against type VII collagen results in subepidermal blistering in mice

21 January 2018

1 reference

12 December 2020

A 10% ready-to-use intravenous human immunoglobulin offers potential economic advantages over a lyophilized product in the treatment of primary immunodeficiency

1 reference

12 December 2020

Immunological studies on glycated human IgG

1 reference

12 December 2020

Galactosylation of IgG associated oligosaccharides: reduction in patients with adult and juvenile onset rheumatoid arthritis and relation to disease activity

1 reference

12 December 2020

Rapid formation of advanced glycation end products by intermediate metabolites of glycolytic pathway and polyol pathway

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1422481112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

0 references

release_ftn3pnmdk5h7vecyj6diquwvva

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ftn3pnmdk5h7vecyj6diquwvva

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

25733881

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25733881%20AND%20SRC:MED&resulttype=core&format=json