Searching for novel cell cycle regulators in Trypanosoma brucei with an RNA interference screen (Q33421107)

26 July 2017

title

Searching for novel cell cycle regulators in Trypanosoma brucei with an RNA interference screen (English)

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26 July 2017

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conserved protein, unknown function

5 February 2019

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5 February 2019

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5 February 2019

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5 February 2019

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5 February 2019

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5 February 2019

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Tetratricopeptide repeat protein 29, putative

5 February 2019

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RNA-binding protein, putative

5 February 2019

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5 February 2019

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Right handed beta helix region, putative

5 February 2019

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paraflagellar rod protein

5 February 2019

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ubiquinol-cytochrome c reductase, putative

5 February 2019

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invariant surface glycoprotein, putative

5 February 2019

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5 February 2019

Mitochondrial SSU ribosomal protein, putative

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5 February 2019

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5 February 2019

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5 February 2019

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PH domain containing protein, putative

5 February 2019

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5 February 2019

splicing factor 3a, putative

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5 February 2019

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5 February 2019

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zinc-binding protein (Yippee), putative

5 February 2019

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telomerase-associated protein, putative

5 February 2019

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protein kinase C substrate protein, heavy chain, putative

5 February 2019

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ATPase family associated with various cellular activities (AAA), putative

5 February 2019

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6 February 2019

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expression site-associated gene (ESAG) protein, putative

6 February 2019

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6 February 2019

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non-canonical ubiquiting-conjugating enzyme 1, putative

6 February 2019

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paraflagellar rod protein, putative

6 February 2019

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6 February 2019

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6 February 2019

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6 February 2019

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variant surface glycoprotein (VSG)-related, putative

6 February 2019

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ubiquinol-cytochrome c reductase, putative

6 February 2019

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monoglyceride lipase, putative

6 February 2019

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calcium/calmodulin-dependent protein kinase, putative

6 February 2019

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metallo-peptidase, Clan ME, Family M16

6 February 2019

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6 February 2019

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fructose-1,6-bisphosphatase

6 February 2019

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6 February 2019

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6 February 2019

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6 February 2019

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predicted zinc finger protein

6 February 2019

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6 February 2019

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retrotransposon hot spot protein 3 (RHS3), putative

6 February 2019

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6 February 2019

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CHAT domain containing protein, putative

6 February 2019

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6 February 2019

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vacuolar protein sorting-associated protein 35, putative

6 February 2019

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6 February 2019

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6 February 2019

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6 February 2019

Inhibitor of F1-ATPase

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Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5), putative

6 February 2019

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6 February 2019

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6 February 2019

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Kinesin associated protein, putative

6 February 2019

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6 February 2019

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NADH-ubiquinone oxidoreductase complex I subunit, putative

6 February 2019

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6 February 2019

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PA26 p53-induced protein (sestrin), putative

6 February 2019

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CAMK/CAMKL family protein kinase, putative

6 February 2019

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receptor-type adenylate cyclase GRESAG 4, putative

6 February 2019

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6 February 2019

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6 February 2019

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Adenylate/guanylate cyclase, putative

6 February 2019

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6 February 2019

Dithiol glutaredoxin 1

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6 February 2019

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6 February 2019

aminopeptidase, putative

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nucleobase/nucleoside transporter 8.2

6 February 2019

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nucleobase/nucleoside transporter 8.3

6 February 2019

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TFIIF-stimulated CTD phosphatase, putative

6 February 2019

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6 February 2019

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myo-inositol/proton symporter (MIT)

6 February 2019

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Tex-like protein N-terminal domain/Helix-hairpin-helix motif containing protein, putative

6 February 2019

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protein phosphatase 1, putative

6 February 2019

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6 February 2019

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CobW/HypB/UreG, nucleotide-binding domain containing protein, putative

6 February 2019

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aminomethyltransferase, mitochondrial, putative

6 February 2019

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6 February 2019

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Mut7-C RNAse domain containing protein, putative

6 February 2019

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6 February 2019

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protein phosphatase 4, putative

6 February 2019

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non-canonical ubiquiting-conjugating enzyme 1, putative

7 February 2019

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DIS3-like exonuclease, putative

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phosphatidylinositol 3-related kinase, putative (fragment)

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Tansy C Hammarton

5

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Jeremy C. Mottram

object named as

Jeremy C Mottram

4

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author name string

Séverine Monnerat

1

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26 July 2017

Caroline Clucas

2

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26 July 2017

Elaine Brown

3

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26 July 2017

publication date

23 March 2009

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26 July 2017

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26 July 2017

volume

2

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26 July 2017

page(s)

46

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Rapamycin inhibits trypanosome cell growth by preventing TOR complex 2 formation

26 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

p166, a link between the trypanosome mitochondrial DNA and flagellum, mediates genome segregation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Genome-scale RNAi profiling of cell division in human tissue culture cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Cell cycle regulation in Trypanosoma brucei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Genome-wide functional analysis of human cell-cycle regulators.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Chromosome-wide analysis of gene function by RNA interference in the african trypanosome.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Conserved and specific functions of axoneme components in trypanosome motility

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Flagellar motility contributes to cytokinesis in Trypanosoma brucei and is modulated by an evolutionarily conserved dynein regulatory system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

The Genome of the African Trypanosome Trypanosoma brucei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Terminal cytokinesis events uncovered after an RNAi screen

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Stage-specific differences in cell cycle control in Trypanosoma brucei revealed by RNA interference of a mitotic cyclin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Glycolysis modulates trypanosome glycoprotein expression as revealed by an RNAi library

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Molecular dissection of cytokinesis by RNA interference in Drosophila cultured cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Deletion of a novel protein kinase with PX and FYVE-related domains increases the rate of differentiation of Trypanosoma brucei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

The exosome of Trypanosoma brucei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Dyneins across eukaryotes: a comparative genomic analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Okadaic acid overcomes the blocked cell cycle caused by depleting Cdc2-related kinases in Trypanosoma brucei

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Flagellar motility is required for the viability of the bloodstream trypanosome

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

Genome-wide survey of protein kinases required for cell cycle progression.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

RNAit: an automated web-based tool for the selection of RNAi targets in Trypanosoma brucei.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

An RNAi screen of the RRM-domain proteins of Trypanosoma brucei

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2674452

The protein phosphatase inhibitor okadaic acid induces defects in cytokinesis and organellar genome segregation in Trypanosoma brucei

10 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19309510

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Double-stranded RNA interference in Trypanosoma brucei using head-to-head promoters

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19309510

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1756-0500-2-46

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Dimensions Publication ID

26 July 2017

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https://scigraph.springernature.com/pub.10.1186/1756-0500-2-46

9 September 2019

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26 July 2017

1 reference