A subnanogram API LC/MS/MS quantitation method for depsipeptide FR901228 and its preclinical pharmacokinetics (Q33421623)

26 July 2017

title

A subnanogram API LC/MS/MS quantitation method for depsipeptide FR901228 and its preclinical pharmacokinetics (English)

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26 July 2017

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Li Z

1

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26 July 2017

Chan KK

series ordinal

2

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26 July 2017

publication date

1 February 2000

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Journal of Pharmaceutical and Biomedical Analysis

26 July 2017

published in

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26 July 2017

volume

22

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26 July 2017

issue

1

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26 July 2017

page(s)

33-44

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FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity

26 July 2017

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FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. II. Structure determination

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7 January 2021

FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. III. Antitumor activities on experimental tumors in mice

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Effects of a novel antitumor depsipeptide, FR901228, on human breast cancer cells.

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FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor.

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7 January 2021

Depsipeptide (FR901228, NSC-630176) pharmacokinetics in the rat by LC/MS/MS

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7 January 2021

High-speed liquid chromatography/tandem mass spectrometry for the determination of drugs in biological samples

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7 January 2021

High-performance liquid chromatographic-electrospray mass spectrometric determination of morphine and its 3- and 6-glucuronides: application to pharmacokinetic studies

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7 January 2021

Development and validation of an LC-MS-MS method for the determination of terfenadine in human plasma

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7 January 2021

Determination of a substance P antagonist in human plasma and urine using high-performance liquid chromatography with ultraviolet absorbance and tandem mass spectrometric detection

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7 January 2021

Microsample determination of lovastatin and its hydroxy acid metabolite in mouse and rat plasma by liquid chromatography/ionspray tandem mass spectrometry

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7 January 2021

Quantitative analysis of mevinolinic acid in human plasma by high-performance liquid chromatography coupled with negative-ion electrospray tandem mass spectrometry

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7 January 2021

Quantitative determination of Orlistat (tetrahydrolipostatin, Ro 18-0647) in human plasma by high-performance liquid chromatography coupled with ion spray tandem mass spectrometry

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Matrix effect in quantitative LC/MS/MS analyses of biological fluids: a method for determination of finasteride in human plasma at picogram per milliliter concentrations

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7 January 2021

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Identifiers

DOI

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26 July 2017

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