A phase II study to evaluate LY2603618 in combination with gemcitabine in pancreatic cancer patients. (Q33439342)

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2 April 2020

title

A phase II study to evaluate LY2603618 in combination with gemcitabine in pancreatic cancer patients (English)

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2 April 2020

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2

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Stefano Cascinu

10

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author name string

Berta Laquente

1

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2 April 2020

Donald Richards

3

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Gerald Illerhaus

4

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David Z Chang

5

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2 April 2020

George Kim

6

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2 April 2020

Philip Stella

7

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Dirk Richel

8

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Cezary Szcylik

9

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2 April 2020

G L Frassineti

11

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2 April 2020

Tudor Ciuleanu

12

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Karla Hurt

13

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2 April 2020

Scott Hynes

14

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Ji Lin

15

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Aimee Bence Lin

16

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Daniel Von Hoff

17

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Emiliano Calvo

18

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language of work or name

English

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publication date

15 February 2017

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2 April 2020

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volume

17

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2 April 2020

issue

1

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2 April 2020

page(s)

137

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Phase I Study of GDC-0425, a Checkpoint Kinase 1 Inhibitor, in Combination with Gemcitabine in Patients with Refractory Solid Tumors

2 April 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312529

Phase I Study of CHK1 Inhibitor LY2603618 in Combination with Gemcitabine in Patients with Solid Tumors

21 June 2018

1 reference

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Systemic therapy for advanced pancreatic cancer: individualising cytotoxic therapy

21 June 2018

1 reference

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New challenges in perioperative management of pancreatic cancer

21 June 2018

1 reference

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Phase I dose-escalation trial of checkpoint kinase 1 inhibitor MK-8776 as monotherapy and in combination with gemcitabine in patients with advanced solid tumors.

21 June 2018

1 reference

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Preclinical analyses and phase I evaluation of LY2603618 administered in combination with pemetrexed and cisplatin in patients with advanced cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312529

Phase I dose-escalation study of AZD7762, a checkpoint kinase inhibitor, in combination with gemcitabine in US patients with advanced solid tumors

21 June 2018

1 reference

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Randomized, double-blind, phase II trial comparing gemcitabine-cisplatin plus the LTB4 antagonist LY293111 versus gemcitabine-cisplatin plus placebo in first-line non-small-cell lung cancer

21 June 2018

1 reference

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CHEK again: revisiting the development of CHK1 inhibitors for cancer therapy

21 June 2018

1 reference

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Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine

21 June 2018

1 reference

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Characterization and preclinical development of LY2603618: a selective and potent Chk1 inhibitor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312529

nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer

21 June 2018

1 reference

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Phase I dose-escalation study to examine the safety and tolerability of LY2603618, a checkpoint 1 kinase inhibitor, administered 1 day after pemetrexed 500 mg/m(2) every 21 days in patients with cancer

21 June 2018

1 reference

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Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial

21 June 2018

1 reference

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FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

21 June 2018

1 reference

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Quantification of gemcitabine incorporation into human DNA by LC/MS/MS as a surrogate measure for target engagement.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5312529

Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer

21 June 2018

1 reference

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New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)

21 June 2018

1 reference

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Meta-analysis of randomized trials: evaluation of benefit from gemcitabine-based combination chemotherapy applied in advanced pancreatic cancer

21 June 2018

1 reference

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A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancer

21 June 2018

1 reference

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Surgical treatment of pancreatic adenocarcinoma; actual survival and prognostic factors in 343 patients

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS12885-017-3131-X

10.1186/S12885-017-3131-X

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28202004%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

2 April 2020

0 references

1 reference

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2 April 2020

PubMed publication ID

28202004

1 reference