Covalent cross-linking of glutathione and carnosine to proteins by 4-oxo-2-nonenal (Q33456073)

26 July 2017

title

Covalent cross-linking of glutathione and carnosine to proteins by 4-oxo-2-nonenal (English)

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26 July 2017

1 reference

Xiaochun Zhu

1

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26 July 2017

Molly M Gallogly

2

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26 July 2017

John J Mieyal

3

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26 July 2017

Vernon E Anderson

4

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26 July 2017

Lawrence M Sayre

5

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26 July 2017

publication date

1 June 2009

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Chemical Research in Toxicology

26 July 2017

published in

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26 July 2017

volume

22

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26 July 2017

issue

6

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26 July 2017

page(s)

1050-1059

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Regulation by reversible S-glutathionylation: molecular targets implicated in inflammatory diseases

26 July 2017

cites work

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Mechanisms of reversible protein glutathionylation in redox signaling and oxidative stress

21 June 2018

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A novel 4-oxo-2(E)-nonenal-derived endogenous thiadiazabicyclo glutathione adduct formed during cellular oxidative stress.

21 June 2018

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Protein adducts generated from products of lipid oxidation: focus on HNE and one.

21 June 2018

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21 June 2018

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Carnosine and carnosine-related antioxidants: a review

21 June 2018

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4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal

21 June 2018

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Glutathione conjugates of 4-hydroxy-2(E)-nonenal as biomarkers of hepatic oxidative stress-induced lipid peroxidation in rats.

21 June 2018

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Glutaredoxin: role in reversible protein s-glutathionylation and regulation of redox signal transduction and protein translocation

21 June 2018

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Glutathione-dependent bioactivation of haloalkanes and haloalkenes

21 June 2018

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Mass spectroscopic characterization of protein modification by 4-hydroxy-2-(E)-nonenal and 4-oxo-2-(E)-nonenal.

21 June 2018

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21 June 2018

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Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Functional implications of structural differences between variants A and B of bovine beta-lactoglobulin

21 June 2018

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Simultaneous determination of acrolein, malonaldehyde and 4-hydroxy-2-nonenal produced from lipids oxidized with Fenton's reagent

21 June 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 June 2018

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Role for an episulfonium ion in S-(2-chloroethyl)-DL-cysteine-induced cytotoxicity and its reaction with glutathione

21 June 2018

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Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

21 June 2018

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Residue-specific adduction of tubulin by 4-hydroxynonenal and 4-oxononenal causes cross-linking and inhibits polymerization

21 June 2018

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Covalent adduction of human serum albumin by 4-hydroxy-2-nonenal: kinetic analysis of competing alkylation reactions.

31 October 2018

1 reference

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LC-ESI-MS/MS determination of 4-hydroxy-trans-2-nonenal Michael adducts with cysteine and histidine-containing peptides as early markers of oxidative stress in excitable tissues.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857574

A novel lipid hydroperoxide-derived cyclic covalent modification to histone H4.

31 October 2018

1 reference

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Model Studies on Protein Side Chain Modification by 4-Oxo-2-nonenal

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2857574

Detoxification of cytotoxic alpha,beta-unsaturated aldehydes by carnosine: characterization of conjugated adducts by electrospray ionization tandem mass spectrometry and detection by liquid chromatography/mass spectrometry in rat skeletal muscle.

31 October 2018

1 reference

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Thiolation of protein-bound carcinogenic aldehyde. An electrophilic acrolein-lysine adduct that covalently binds to thiols

31 October 2018

1 reference

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Determination of free amino groups in proteins by trinitrobenzenesulfonic acid

31 October 2018

1 reference

12 December 2020

Role of cardiac glutathione transferase and of the glutathione S-conjugate export system in biotransformation of 4-hydroxynonenal in the heart

1 reference

12 December 2020

Glutathione conjugation of 4-hydroxy-trans-2,3-nonenal in the rat in vivo, the isolated perfused liver and erythrocytes

1 reference

12 December 2020

Oxidative stress in Alzheimer's disease

1 reference

12 December 2020

Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidation

1 reference

12 December 2020

Mass spectrometric evidence for long-lived protein adducts of 4-oxo-2-nonenal

1 reference

12 December 2020

Intermediates in the Paal-Knorr synthesis of pyrroles. 4-Oxoaldehydes

1 reference

12 December 2020

Complete structure elucidation of a globular protein by particle beam liquid chromatography-Fourier transform infrared spectrometry and electrospray liquid chromatography-mass spectrometry. Sequence and conformation of beta-lactoglobulin

1 reference

12 December 2020

Ability of carnosine and other skeletal muscle components to quench unsaturated aldehydic lipid oxidation products

1 reference

12 December 2020

Structural characterization of a 4-hydroxy-2-alkenal-derived fluorophore that contributes to lipoperoxidation-dependent protein cross-linking in aging and degenerative disease

1 reference

12 December 2020

Chemical nature of stochastic generation of protein-based carbonyls: metal-catalyzed oxidation versus modification by products of lipid oxidation

1 reference

12 December 2020

Mercapturic acid conjugates as urinary end metabolites of the lipid peroxidation product 4-hydroxy-2-nonenal in the rat

1 reference

12 December 2020

Long-lived 4-oxo-2-enal-derived apparent lysine michael adducts are actually the isomeric 4-ketoamides

1 reference

12 December 2020

Mass spectrometry in the analysis of glutathione conjugates

1 reference

12 December 2020

Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonenal

1 reference

12 December 2020

Identifiers

DOI

10.1021/TX9000144

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26 July 2017

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26 July 2017

1 reference