HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: an IgA gene and functional analysis (Q33479955)

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scientific article published on 8 July 2009

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English	HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: an IgA gene and functional analysis	scientific article published on 8 July 2009

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scholarly article

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Europe PubMed Central

PubMed publication ID

27 July 2017

HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(+) cell infection: an IgA gene and functional analysis (English)

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Europe PubMed Central

PubMed publication ID

27 July 2017

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L Lopalco

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M Bomsel

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author name string

D Tudor

1

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Europe PubMed Central

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27 July 2017

M Derrien

2

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Europe PubMed Central

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27 July 2017

L Diomede

3

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Europe PubMed Central

PubMed publication ID

27 July 2017

A-S Drillet

4

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Europe PubMed Central

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27 July 2017

M Houimel

5

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Europe PubMed Central

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27 July 2017

C Moog

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27 July 2017

J-M Reynes

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27 July 2017

publication date

8 July 2009

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27 July 2017

Mucosal Immunology

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27 July 2017

2

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27 July 2017

5

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Europe PubMed Central

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27 July 2017

412-426

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Europe PubMed Central

PubMed publication ID

27 July 2017

Not just sheer luck! Immune correlates of protection against HIV-1 infection.

1 reference

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Mucosal immune responses in the genital tract of HIV-1-exposed uninfected women

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Cervicovaginal anti-HIV antibodies in HIV-seronegative female sex workers in Abidjan, Côte d'Ivoire

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21 January 2018

Predictive value of anti-cell and anti-human immunodeficiency virus (HIV) humoral responses in HIV-1-exposed seronegative cohorts of European and Asian origin.

1 reference

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21 January 2018

Mucosal and plasma IgA from HIV-1-exposed uninfected individuals inhibit HIV-1 transcytosis across human epithelial cells

1 reference

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21 January 2018

Secretory IgA specific for a conserved epitope on gp41 envelope glycoprotein inhibits epithelial transcytosis of HIV-1.

1 reference

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21 January 2018

Cervicovaginal secretory antibodies to human immunodeficiency virus type 1 (HIV-1) that block viral transcytosis through tight epithelial barriers in highly exposed HIV-1-seronegative African women.

1 reference

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Serum IgA of HIV-exposed uninfected individuals inhibit HIV through recognition of a region within the alpha-helix of gp41.

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Cervical HIV-specific IgA in a population of commercial sex workers correlates with repeated exposure but not resistance to HIV.

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Mucosal IgA in exposed, uninfected subjects: evidence for a role in protection against HIV infection

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Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

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Neutralizing antibodies against HIV -- back in the major leagues?

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High-level ability of secretory IgA to block HIV type 1 transcytosis: contrasting secretory IgA and IgG responses to glycoprotein 160.

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Intraepithelial cell neutralization of HIV-1 replication by IgA.

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HIV-1 gp41 envelope residues 650-685 exposed on native virus act as a lectin to bind epithelial cell galactosyl ceramide

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Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor

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Galactosyl ceramide expressed on dendritic cells can mediate HIV-1 transfer from monocyte derived dendritic cells to autologous T cells

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Both lipid environment and pH are critical for determining physiological solution structure of 3-D-conserved epitopes of the HIV-1 gp41-MPER peptide P1.

1 reference

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21 January 2018

Transcytosis-blocking abs elicited by an oligomeric immunogen based on the membrane proximal region of HIV-1 gp41 target non-neutralizing epitopes.

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21 January 2018

A mucosally targeted subunit vaccine candidate eliciting HIV-1 transcytosis-blocking Abs.

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Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens

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A definitive set of oligonucleotide primers for amplifying human V regions

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Antiviral properties of two trimeric recombinant gp41 proteins

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A general vector, pASK84, for cloning, bacterial production, and single-step purification of antibody Fab fragments

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HIV-1 mutants escaping neutralization by the human antibodies 2F5, 2G12, and 4E10: in vitro experiments versus clinical studies

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21 January 2018

Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.

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21 January 2018

Difficulties in eliciting broadly neutralizing anti-HIV antibodies are not explained by cardiolipin autoreactivity

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Reassessment of autoreactivity of the broadly neutralizing HIV antibodies 4E10 and 2F5 and retrospective analysis of clinical safety data

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Recent advances in the characterization of HIV-1 neutralization assays for standardized evaluation of the antibody response to infection and vaccination

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Regional specialization in the mucosal immune system: what happens in the microcompartments?

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Phage display technology: clinical applications and recent innovations

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Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design

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21 January 2018

The long third complementarity-determining region of the heavy chain is important in the activity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5.

1 reference

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21 January 2018

Molecular profile of an antibody response to HIV-1 as probed by combinatorial libraries

1 reference

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Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire

1 reference

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21 January 2018

HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers

1 reference

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21 January 2018

Neutralizing antibodies in mucosal secretions: IgG or IgA?

1 reference

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Entry of viruses through the epithelial barrier: pathogenic trickery

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The polymeric immunoglobulin receptor. A model protein to study transcytosis

1 reference

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Immunization of mice with recombinant gp41 in a systemic prime/mucosal boost protocol induces HIV-1-specific serum IgG and secretory IgA antibodies

1 reference

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The caveolin-1 binding domain of HIV-1 glycoprotein gp41 is an efficient B cell epitope vaccine candidate against virus infection

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Inhibition of HIV-1 infectivity and epithelial cell transfer by human monoclonal IgG and IgA antibodies carrying the b12 V region

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21 January 2018

Characterization of human class-switched polymeric (immunoglobulin M [IgM] and IgA) anti-human immunodeficiency virus type 1 antibodies 2F5 and 2G12.

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Crystal structure of the complex between the F(ab)' fragment of the cross-neutralizing anti-HIV-1 antibody 2F5 and the F(ab) fragment of its anti-idiotypic antibody 3H6

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Somatic generation of antibody diversity

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Diversity in the CDR3 region of V(H) is sufficient for most antibody specificities

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Conformations of the third hypervariable region in the VH domain of immunoglobulins

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The role of antibody polyspecificity and lipid reactivity in binding of broadly neutralizing anti-HIV-1 envelope human monoclonal antibodies 2F5 and 4E10 to glycoprotein 41 membrane proximal envelope epitopes

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Prevention of virus transmission to macaque monkeys by a vaginally applied monoclonal antibody to HIV-1 gp120.

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The Role of Mucosal Immunity in Prevention of HIV Transmission

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Progress towards an AIDS mucosal vaccine: an overview

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The paradoxical effects of using antiretroviral-based microbicides to control HIV epidemics

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HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women

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Assembly of combinatorial antibody libraries on phage surfaces: the gene III site

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Selection of high-affinity phage antibodies from phage display libraries

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Use of Thiophilic Adsorption Chromatography for the One-Step Purification of a Bacterially Produced Antibody Fab Fragment without the Need for an Affinity Tag

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Passive transfer studies to elucidate the role of antibody-mediated protection against HIV-1.

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Natural mucosal antibodies reactive with first extracellular loop of CCR5 inhibit HIV-1 transport across human epithelial cells

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Transcytosis of infectious human immunodeficiency virus across a tight human epithelial cell line barrier

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Early events in HIV transmission through a human reconstructed vaginal mucosa

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The ‘immunologic advantage’ of HIV-exposed seronegative individuals

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Apolipoprotein B mRNA–Editing Enzyme, Catalytic Polypeptide–Like 3G: A Possible Role in the Resistance to HIV of HIV‐Exposed Seronegative Individuals

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Cross-Clade HIV-1–Specific Neutralizing IgA in Mucosal and Systemic Compartments of HIV-1–Exposed, Persistently Seronegative Subjects

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Unravelling antibody genes

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Molecular determinants of the human antibody response to HIV-1: implications for disease control

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HIV-Specific Antibodies But Not T-Cell Responses Are Associated With Protection in Seronegative Partners of HIV-1-Infected Individuals in Cambodia

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Intracellular Neutralization of HIV Transcytosis across Tight Epithelial Barriers by Anti-HIV Envelope Protein dIgA or IgM

1 reference

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A conserved tryptophan-rich motif in the membrane-proximal region of the human immunodeficiency virus type 1 gp41 ectodomain is important for Env-mediated fusion and virus infectivity.

1 reference

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Involvement of Fc gamma RI (CD64) in the mechanism of HIV-1 inhibition by polyclonal IgG purified from infected patients in cultured monocyte-derived macrophages

1 reference

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7 January 2021

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inferred from DOI database lookup

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10.1038/MI.2009.89

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Europe PubMed Central

PubMed publication ID

27 July 2017

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

27 July 2017

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