Nerve agent analogues that produce authentic soman, sarin, tabun, and cyclohexyl methylphosphonate-modified human butyrylcholinesterase (Q33498052)

27 July 2017

title

Nerve agent analogues that produce authentic soman, sarin, tabun, and cyclohexyl methylphosphonate-modified human butyrylcholinesterase (English)

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27 July 2017

3

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author name string

Cynthia Gilley

1

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27 July 2017

Mary MacDonald

2

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27 July 2017

Florian Nachon

3

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27 July 2017

Lawrence M Schopfer

4

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27 July 2017

Jun Zhang

5

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27 July 2017

John R Cashman

6

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27 July 2017

Oksana Lockridge

7

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27 July 2017

publication date

1 October 2009

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Chemical Research in Toxicology

27 July 2017

published in

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27 July 2017

volume

22

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27 July 2017

issue

10

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27 July 2017

page(s)

1680-1688

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Chemical synthesis of two series of nerve agent model compounds and their stereoselective interaction with human acetylcholinesterase and human butyrylcholinesterase

27 July 2017

cites work

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Aging of cholinesterases phosphylated by tabun proceeds through O-dealkylation

21 June 2018

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Pseudo-esterase activity of human albumin: slow turnover on tyrosine 411 and stable acetylation of 82 residues including 59 lysines

21 June 2018

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Aging pathways for organophosphate-inhibited human butyrylcholinesterase, including novel pathways for isomalathion, resolved by mass spectrometry

21 June 2018

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LARGE SCALE PURIFICATION OF BUTYRYLCHOLINESTERASE FROM HUMAN PLASMA SUITABLE FOR INJECTION INTO MONKEYS; A POTENTIAL NEW THERAPEUTIC FOR PROTECTION AGAINST COCAINE AND NERVE AGENT TOXICITY.

21 June 2018

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Role of water in aging of human butyrylcholinesterase inhibited by echothiophate: the crystal structure suggests two alternative mechanisms of aging

21 June 2018

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Direct analysis of the kinetic profiles of organophosphate-acetylcholinesterase adducts by MALDI-TOF mass spectrometry

21 June 2018

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Cleavage N-terminal to proline: analysis of a database of peptide tandem mass spectra

21 June 2018

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Crystal structures of aged phosphonylated acetylcholinesterase: nerve agent reaction products at the atomic level

21 June 2018

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Toxicity of the organophosphate chemical warfare agents GA, GB, and VX: implications for public protection

21 June 2018

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Identification and characterization of posttranslational modifications of proteins by MALDI ion trap mass spectrometry

21 June 2018

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Importance of aspartate-70 in organophosphate inhibition, oxime re-activation and aging of human butyrylcholinesterase

21 June 2018

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Sarin poisoning on Tokyo subway

21 June 2018

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Phosphopeptide analysis by matrix-assisted laser desorption time-of-flight mass spectrometry

21 June 2018

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Specificity and orientation of trigonal carboxyl esters and tetrahedral alkylphosphonyl esters in cholinesterases

21 June 2018

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Analogues with fluorescent leaving groups for screening and selection of enzymes that efficiently hydrolyze organophosphorus nerve agents

21 June 2018

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Structural and mutational studies of organophosphorus hydrolase reveal a cryptic and functional allosteric-binding site

31 October 2018

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Retrospective detection of exposure to organophosphorus anti-cholinesterases: mass spectrometric analysis of phosphylated human butyrylcholinesterase.

31 October 2018

1 reference

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Stereoselective detoxification of chiral sarin and soman analogues by phosphotriesterase.

31 October 2018

1 reference

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Dimethylphosphoryl-inhibited human cholinesterases: inhibition, reactivation, and aging kinetics.

31 October 2018

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Asymmetric fluorogenic organophosphates for the development of active organophosphate hydrolases with reversed stereoselectivity

31 October 2018

1 reference

12 December 2020

Phosphonylation of purified human, canine and porcine cholinesterase by soman

1 reference

12 December 2020

The pH dependence of dealkylation in soman-inhibited cholinesterases and their mutants: further evidence for a push-pull mechanism

1 reference

12 December 2020

Detection of human butyrylcholinesterase-nerve gas adducts by liquid chromatography-mass spectrometric analysis after in gel chymotryptic digestion

1 reference

12 December 2020

Electrospray tandem mass spectrometric studies of phosphopeptides and phosphopeptide analogues

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12 December 2020

Organophosphorus acid anhydride hydrolase activity in human butyrylcholinesterase: synergy results in a somanase

1 reference

12 December 2020

Studies using a monoclonal antibody against soman

1 reference

12 December 2020

Identifiers

DOI

10.1021/TX900090M

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27 July 2017

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27 July 2017

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