Heparin-induced thrombocytopenia. Pathogenesis, frequency, avoidance and management (Q33501004)

27 July 2017

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title

Heparin-induced thrombocytopenia. Pathogenesis, frequency, avoidance and management (English)

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27 July 2017

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1

T E Warkentin

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27 July 2017

publication date

1 November 1997

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27 July 2017

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27 July 2017

volume

17

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27 July 2017

issue

5

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27 July 2017

page(s)

325-341

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Heparin modifies platelet count and function in patients who have undergone thrombolytic therapy for acute myocardial infarction

27 July 2017

cites work

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12 December 2020

Determinants of donor platelet variability when testing for heparin-induced thrombocytopenia

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12 December 2020

Heparin-associated thrombocytopenia: immune complexes are attached to the platelet membrane by the negative charge of highly sulphated oligosaccharides

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12 December 2020

Use of recombinant hirudin as antithrombotic treatment in patients with heparin-induced thrombocytopenia

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12 December 2020

Absence of in vitro cross-reaction of pentasaccharide with the plasma heparin-dependent factor of twenty-five patients with heparin-associated thrombocytopenia

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12 December 2020

Immunoglobulin G from patients with heparin-induced thrombocytopenia binds to a complex of heparin and platelet factor 4.

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12 December 2020

Antibodies from patients with heparin-induced thrombocytopenia/thrombosis are specific for platelet factor 4 complexed with heparin or bound to endothelial cells

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12 December 2020

Heparin-induced thrombocytopenia (HIT): an overview of 230 patients treated with orgaran (Org 10172)

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12 December 2020

Treatment of heparin-associated thrombocytopenia and thrombosis with low molecular weight heparin (CY 216).

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12 December 2020

Heparin-induced thrombocytopenia: discrepancy between the presence of IgG cross-reacting in vitro with fraxiparine and its successful clinical use

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12 December 2020

Laboratory diagnosis of heparin-associated thrombocytopenia and comparison of platelet aggregation test, heparin-induced platelet activation test, and platelet factor 4/heparin enzyme-linked immunosorbent assay

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12 December 2020

Role of Fc gamma RIIA gene polymorphism in human platelet activation by monoclonal antibodies

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12 December 2020

Rapid anticoagulation using ancrod for heparin-induced thrombocytopenia

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12 December 2020

Fc gamma RIIA H/R 131 polymorphism, subclass-specific IgG anti-heparin/platelet factor 4 antibodies and clinical course in patients with heparin-induced thrombocytopenia and thrombosis

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12 December 2020

Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin-induced thrombocytopenia.

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12 December 2020

Heparin-Associated Thrombosis Without Thrombocytopenia

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12 December 2020

Heparin-induced thrombocytopenia and thrombosis

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12 December 2020

Orgaran (Org 10172): its pharmacological profile in experimental models

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12 December 2020

Heparin-associated thrombocytopenia: no association of immune response with HLA.

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12 December 2020

Heparin-induced thrombocytopenia: IgG-mediated platelet activation, platelet microparticle generation, and altered procoagulant/anticoagulant balance in the pathogenesis of thrombosis and venous limb gangrene complicating heparin-induced thrombocyto

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12 December 2020

Thrombolysis to treat arterial thrombotic complications of heparin-induced thrombocytopenia

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12 December 2020

Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia.

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12 December 2020

Treatment of heparin-induced thrombocytopenia by use of argatroban, a synthetic thrombin inhibitor

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12 December 2020

Aspirin prevents heparin-induced platelet aggregation in vivo

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12 December 2020

A diagnostic test for heparin-induced thrombocytopenia: detection of platelet microparticles using flow cytometry

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12 December 2020

Platelets of patients with peripheral arterial disease are hypersensitive to heparin

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12 December 2020

Differential expression of Fc gamma RIIA, Fc gamma RIIB and Fc gamma RIIC in hematopoietic cells: analysis of transcripts

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12 December 2020

Characterization of the humoral immune response in heparin-induced thrombocytopenia

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12 December 2020

Heparin-induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin

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12 December 2020

Heparin-induced thrombocytopenia with associated disseminated intravascular coagulation

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12 December 2020

Heparin-induced thrombocytopenia in hemodialysis patients

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12 December 2020

Heparin induced thrombocytopenia with thrombotic and hemorrhagic manifestations

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12 December 2020

Heparin-associated thrombocytopenia: the antibody is not heparin specific

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12 December 2020

Intraoperative urokinase as an alternative to heparin for patients with suspected heparin-induced thrombocytopenia requiring arterial reconstruction: report of a case and review of the literature.

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12 December 2020

Surgical management of heparin-associated thrombocytopenia. Strategies in the treatment of venous and arterial thromboembolism

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12 December 2020

Heparin-induced thrombocytopenia and vena cava filter. Difficulties of treatment

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12 December 2020

Antigen Generation in Heparin-Associated Thrombocytopenia: The Nonimmunologic Type and the Immunologic Type Are Closely Linked in Their Pathogenesis

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12 December 2020

Heparin-induced thrombocytopenia and pentosan polysulfate: treatment with a low molecular weight heparin despite in vitro platelet aggregation

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12 December 2020

[Thrombopenia caused by heparin: discordance between clinical efficacy of enoxaparin and the platelet aggregation tests in vitro]

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12 December 2020

Structural polymorphism of the human monocyte 40 kilodalton Fc receptor for IgG

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12 December 2020

Mutation in blood coagulation factor V associated with resistance to activated protein C.

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12 December 2020

A rapid and sensitive test for diagnosing heparin-associated thrombocytopenia

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12 December 2020

Heparin-induced thrombocytopenia with thrombosis of the aorta, iliac arteries and right axillary vein successfully treated by low-molecular weight heparin

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12 December 2020

Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors

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12 December 2020

Heparin-induced thrombocytopenia: laboratory investigation and confirmation of diagnosis

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12 December 2020

Critical ischemia during heparin-induced thrombocytopenia. Treatment by intra-arterial streptokinase

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12 December 2020

A diagnostic test for heparin-induced thrombocytopenia

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12 December 2020

Complications from heparin-induced thrombocytopenia in patients undergoing cardiopulmonary bypass

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12 December 2020

Low-molecular weight heparin in the therapy of heparin-induced thrombocytopenia

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12 December 2020

Heparin-induced thrombocytopenia: effect of heparin platelet antibody on platelets

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12 December 2020

Persistent heparin induced thrombocytopenia despite therapy with low molecular weight heparin

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12 December 2020

Presence of autoantibodies to interleukin-8 or neutrophil-activating peptide-2 in patients with heparin-associated thrombocytopenia

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12 December 2020

Heparin-induced thrombocytopenia complicated by hematoma of the adrenal glands and acute adrenal insufficiency

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12 December 2020

Thrombopenia induced by standard heparin. Therapeutic attempt using a low molecular weight heparin

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12 December 2020

Characterization of the structural requirements for a carbohydrate based anticoagulant with a reduced risk of inducing the immunological type of heparin-associated thrombocytopenia.

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12 December 2020

Ancrod: A practical alternative to heparin

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12 December 2020

Heparin-induced immune thrombocytopenia

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12 December 2020

The pathogenesis of venous limb gangrene associated with heparin-induced thrombocytopenia

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12 December 2020

A single amino acid in the second Ig-like domain of the human Fc gamma receptor II is critical for human IgG2 binding

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12 December 2020

Response of human platelets to activating monoclonal antibodies: importance of Fc gamma RII (CD32) phenotype and level of expression

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12 December 2020

Comparison of PF4/heparin ELISA assay with the 14C-serotonin release assay in the diagnosis of heparin-induced thrombocytopenia

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12 December 2020

Heparin-induced thrombocytopenia: cross-reactivity between standard heparin, low molecular weight heparin, dalteparin (Fragmin) and heparinoid, danaparoid (Orgaran).

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12 December 2020

Activation of platelets by sera containing IgG1 heparin-dependent antibodies: an explanation for the predominance of the Fc gammaRIIa "low responder" (his131) gene in patients with heparin-induced thrombocytopenia

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12 December 2020

Heparin-associated thrombocytopenia: isolation of the antibody and characterization of a multimolecular PF4-heparin complex as the major antigen

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12 December 2020

Plasma P-selectin is increased in thrombotic consumptive platelet disorders.

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12 December 2020

Heparin-associated thrombocytopenia and thrombosis: a serious clinical problem and potential solution

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12 December 2020

Use of enoxaparin in patients with heparin-induced thrombocytopenia syndrome

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12 December 2020

Single amino acid mutation of Fc gamma receptor is associated with the development of heparin-induced thrombocytopenia

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12 December 2020

Heparin-induced thrombocytopenia

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12 December 2020

The epitope specificity of heparin-induced thrombocytopenia

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12 December 2020

Factor V Leiden and thrombotic complications in heparin-induced thrombocytopenia

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12 December 2020

Antibodies to macromolecular platelet factor 4-heparin complexes in heparin-induced thrombocytopenia: a study of 44 cases.

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12 December 2020

Heparin-associated thrombosis despite normal platelet counts

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12 December 2020

Effect of a new anticoagulant (MD 805) on platelet activation in the hemodialysis circuit

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12 December 2020

Heparin-induced thrombocytopenia: laboratory studies

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12 December 2020

Plasmapheresis. A therapeutic option in the management of heparin-associated thrombocytopenia with thrombosis

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12 December 2020

Heparin-associated acute adrenal insufficiency

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12 December 2020

Transient global amnesia associated with acute heparin-induced thrombocytopenia

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12 December 2020

Heparin-induced thrombocytopenia: studies with a new low molecular weight heparinoid, Org 10172.

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12 December 2020

Heparin-induced thrombocytopenia and thrombosis: clinical and laboratory studies

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12 December 2020

Report of successful use of argatroban as an alternative anticoagulant during coronary stent implantation in a patient with heparin-induced thrombocytopenia and thrombosis syndrome

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12 December 2020

Patients treated with unfractionated heparin during open heart surgery are at high risk to form antibodies reactive with heparin:platelet factor 4 complexes

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12 December 2020

Heparin-induced skin lesions

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12 December 2020

A 14-year study of heparin-induced thrombocytopenia

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12 December 2020

The clinical usefulness of the platelet aggregation test for the diagnosis of heparin-induced thrombocytopenia

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12 December 2020

Heparin-induced thrombocytopenia and thrombosis with spinal ischaemia--recovery of platelet count following a change to a low molecular weight heparin

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12 December 2020

A fatal low-molecular-weight heparin-associated thrombocytopenia after hip surgery: possible usefulness of PF4-heparin ELISA test.

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12 December 2020

Heparin as a cause of thrombus progression. Heparin-associated thrombocytopenia is an important differential diagnosis in paediatric patients even with normal platelet counts

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12 December 2020

Heparin-induced thrombocytopenia: confirmation of diagnosis with in vitro methods

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12 December 2020

Parenteral anticoagulation with the heparinoid Lomoparan (Org 10172) in patients with heparin induced thrombocytopenia and thrombosis

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12 December 2020

Immune endothelial-cell injury in heparin-associated thrombocytopenia

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12 December 2020

Investigation of the mechanisms of monoclonal antibody-induced platelet activation

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12 December 2020

Pathogenicity of IgA and/or IgM antibodies to heparin-PF4 complexes in patients with heparin-induced thrombocytopenia

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12 December 2020

Thrombocytopenia associated with low-molecular-weight heparin

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12 December 2020

Treatment of serious heparin-induced thrombocytopenia by plasma exchange: report on 4 cases

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12 December 2020

Low molecular weight heparin-induced thrombocytopenia and thrombosis.

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12 December 2020

On the role of platelet Fc gamma RIIa phenotype in heparin-induced thrombocytopenia

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12 December 2020

Comparison of the effect of a conventional heparin and a low molecular weight heparinoid on platelet function

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12 December 2020

Cross-reactivity study of low molecular weight heparins and heparinoid in heparin-induced thrombocytopenia

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12 December 2020

10.2165/00002018-199717050-00005

Identifiers

DOI

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Dimensions Publication ID

27 July 2017

1022933503

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