Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays (Q33508083)

27 July 2017

title

Oligomerized pool engineering (OPEN): an 'open-source' protocol for making customized zinc-finger arrays (English)

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27 July 2017

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5

J Keith Joung

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27 July 2017

Morgan L Maeder

1

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27 July 2017

Stacey Thibodeau-Beganny

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2

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27 July 2017

Jeffry D Sander

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3

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27 July 2017

Daniel F Voytas

series ordinal

4

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27 July 2017

publication date

17 September 2009

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27 July 2017

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27 July 2017

volume

4

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27 July 2017

issue

10

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27 July 2017

page(s)

1471-1501

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High-frequency modification of plant genes using engineered zinc-finger nucleases

27 July 2017

cites work

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Rapid mutation of endogenous zebrafish genes using zinc finger nucleases made by Oligomerized Pool ENgineering (OPEN).

21 June 2018

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Targeted transgene integration in plant cells using designed zinc finger nucleases

21 June 2018

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21 June 2018

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Expanding or restricting the target site repertoire of zinc-finger nucleases: the inter-domain linker as a major determinant of target site selectivity

21 June 2018

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21 June 2018

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Progress and prospects: zinc-finger nucleases as gene therapy agents

21 June 2018

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Rapid "open-source" engineering of customized zinc-finger nucleases for highly efficient gene modification

21 June 2018

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Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

21 June 2018

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Zinc-finger nucleases: the next generation emerges

21 June 2018

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Critical parameters for genome editing using zinc finger nucleases

21 June 2018

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Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

21 June 2018

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Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

21 June 2018

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Unexpected failure rates for modular assembly of engineered zinc fingers

21 June 2018

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Targeted gene knockout in mammalian cells by using engineered zinc-finger nucleases.

21 June 2018

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Comparison of zinc finger nucleases for use in gene targeting in mammalian cells

21 June 2018

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Modulation of drug resistance by artificial transcription factors.

21 June 2018

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Engineering Cys2His2 zinc finger domains using a bacterial cell-based two-hybrid selection system

21 June 2018

1 reference

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DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases

21 June 2018

1 reference

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Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

21 June 2018

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Custom-designed zinc finger nucleases: what is next?

21 June 2018

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Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases

21 June 2018

1 reference

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An improved zinc-finger nuclease architecture for highly specific genome editing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Zinc Finger Targeter (ZiFiT): an engineered zinc finger/target site design tool.

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Induction and repair of zinc-finger nuclease-targeted double-strand breaks in Caenorhabditis elegans somatic cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

21 June 2018

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Inhibition of human immunodeficiency virus type 1 replication with artificial transcription factors targeting the highly conserved primer-binding site

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Efficient gene targeting in Drosophila with zinc-finger nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Human immunodeficiency virus type 1 incorporated with fusion proteins consisting of integrase and the designed polydactyl zinc finger protein E2C can bias integration of viral DNA into a predetermined chromosomal region in human cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Zinc finger nucleases: custom-designed molecular scissors for genome engineering of plant and mammalian cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Mammalian gene targeting with designed zinc finger nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Design, engineering, and characterization of zinc finger nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Gene targeting using zinc finger nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Genetic reprogramming of tumor cells by zinc finger transcription factors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Binding of two zinc finger nuclease monomers to two specific sites is required for effective double-strand DNA cleavage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Highly efficient endogenous human gene correction using designed zinc-finger nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Targeted mutagenesis using zinc-finger nucleases in Arabidopsis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Zinc-finger protein-targeted gene regulation: genomewide single-gene specificity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Enhancing Gene Targeting with Designed Zinc Finger Nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Chimeric nucleases stimulate gene targeting in human cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Human zinc fingers as building blocks in the construction of artificial transcription factors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Scanning the human genome with combinatorial transcription factor libraries.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Induction of angiogenesis in a mouse model using engineered transcription factors

21 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

21 June 2018

https://api.crossref.org/works/10.1038%2FNPROT.2009.98

Regulation of transgene expression in plants with polydactyl zinc finger transcription factors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Heritable endogenous gene regulation in plants with designed polydactyl zinc finger transcription factors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

The use of zinc finger peptides to study the role of specific factor binding sites in the chromatin environment.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Activation of vascular endothelial growth factor A transcription in tumorigenic glioblastoma cell lines by an enhancer with cell type-specific DNase I accessibility

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Custom DNA-binding proteins come of age: polydactyl zinc-finger proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Engineering polydactyl zinc-finger transcription factors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Beyond the "recognition code": structures of two Cys2His2 zinc finger/TATA box complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

A bacterial two-hybrid selection system for studying protein-DNA and protein-protein interactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Positive and negative regulation of endogenous genes by designed transcription factors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Toward controlling gene expression at will: specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular building blocks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Genetic analysis of prokaryotic and eukaryotic DNA-binding proteins in Escherichia coli

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Synergy between adjacent zinc fingers in sequence-specific DNA recognition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Zif268 protein-DNA complex refined at 1.6 A: a model system for understanding zinc finger-DNA interactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

High-frequency homologous recombination in plants mediated by zinc-finger nucleases.

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.98

Custom zinc-finger nucleases for use in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.98

Validated zinc finger protein designs for all 16 GNN DNA triplet targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.98

Protein engineering: The fate of fingers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.98

In vivo site-specific DNA methylation with a designed sequence-enabled DNA methylase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.98

Evolution of programmable zinc finger-recombinases with activity in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.98

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.98

High-throughput beta-galactosidase assay for bacterial cell-based reporter systems

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Analysis of zinc fingers optimized via phage display: evaluating the utility of a recognition code

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2858690

Site-specific cleavage of DNA–RNA hybrids by zinc finger/FokI cleavage domain fusions

31 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.98

Controlling gene expression in plants using synthetic zinc finger transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPROT.2009.98

31 March 2020

Identifiers

DOI

10.1038/NPROT.2009.98

1 reference

Dimensions Publication ID

27 July 2017

0 references

1 reference

27 July 2017

1 reference