Targeted induction of endoplasmic reticulum stress induces cartilage pathology (Q33510918)

27 July 2017

Targeted induction of endoplasmic reticulum stress induces cartilage pathology (English)

1 reference

27 July 2017

endoplasmic reticulum

0 references

0 references

1 reference

Richard Wilson

8

0 references

David J. Thornton

David J Thornton

7

0 references

John F. Bateman

John F Bateman

9

0 references

Raymond P Boot-Handford

Raymond P Boot-Handford

14

0 references

Karl E Kadler

Karl E Kadler

12

0 references

author name string

M Helen Rajpar

1

1 reference

27 July 2017

Ben McDermott

2

1 reference

27 July 2017

Louise Kung

3

1 reference

27 July 2017

Rachel Eardley

4

1 reference

27 July 2017

Lynette Knowles

5

1 reference

27 July 2017

Mel Heeran

6

1 reference

27 July 2017

Richard Poulsom

10

1 reference

27 July 2017

Peter Arvan

11

1 reference

27 July 2017

Michael D Briggs

13

1 reference

27 July 2017

16 October 2009

1 reference

27 July 2017

1 reference

27 July 2017

5

1 reference

27 July 2017

10

1 reference

27 July 2017

e1000691

1 reference

Creative Commons Attribution 4.0 International

27 July 2017

start time

16 October 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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21 June 2018

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Localization of the cis-enhancer element for mouse type X collagen expression in hypertrophic chondrocytes in vivo.

21 June 2018

1 reference

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UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

21 June 2018

1 reference

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Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

21 June 2018

1 reference

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ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta

21 June 2018

1 reference

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Regulation of chondrogenesis and chondrocyte differentiation by stress.

21 June 2018

1 reference

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Endoplasmic reticulum stress responses

21 June 2018

1 reference

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The endoplasmic reticulum and the unfolded protein response

21 June 2018

1 reference

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Reduced cell proliferation and increased apoptosis are significant pathological mechanisms in a murine model of mild pseudoachondroplasia resulting from a mutation in the C-terminal domain of COMP

21 June 2018

1 reference

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Signal integration in the endoplasmic reticulum unfolded protein response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Decreased chondrocyte proliferation and dysregulated apoptosis in the cartilage growth plate are key features of a murine model of epiphyseal dysplasia caused by a matn3 mutation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

COL10A1 nonsense and frame-shift mutations have a gain-of-function effect on the growth plate in human and mouse metaphyseal chondrodysplasia type Schmid.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Collagen XXVII is developmentally regulated and forms thin fibrillar structures distinct from those of classical vertebrate fibrillar collagens

21 June 2018

1 reference

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Surviving endoplasmic reticulum stress is coupled to altered chondrocyte differentiation and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

21 June 2018

ER stress and diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Endoplasmic reticulum stress signaling in disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Mediators of endoplasmic reticulum stress-induced apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

21 June 2018

1 reference

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Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

21 June 2018

1 reference

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Intracellular signaling by the unfolded protein response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

A diastrophic dysplasia sulfate transporter (SLC26A2) mutant mouse: morphological and biochemical characterization of the resulting chondrodysplasia phenotype

21 June 2018

1 reference

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Multiple roles of vascular endothelial growth factor (VEGF) in skeletal development, growth, and repair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

The acetylcholinesterase homology region is essential for normal conformational maturation and secretion of thyroglobulin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Therapeutic approaches to protein-misfolding diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

A novel and highly conserved collagen (pro(alpha)1(XXVII)) with a unique expression pattern and unusual molecular characteristics establishes a new clade within the vertebrate fibrillar collagen family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Developmental regulation of the growth plate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Skeletal dysplasias caused by a disruption of skeletal patterning and endochondral ossification.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Pseudoachondroplasia and multiple epiphyseal dysplasia: mutation review, molecular interactions, and genotype to phenotype correlations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Abnormal growth plate function in pigs carrying a dominant mutation in type X collagen

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Schmid type metaphyseal chondrodysplasia: a spondylometaphyseal dysplasia identical to the "Japanese" type

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Mammalian skeletogenesis and extracellular matrix: what can we learn from knockout mice?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Vascular endothelial growth factor (VEGF) directly enhances osteoclastic bone resorption and survival of mature osteoclasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Differential expression of vascular endothelial growth factor mRNA vs protein isoform expression in human breast cancer and relationship to eIF-4E.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Mutations in fibrillar collagens (types I, II, III, and XI), fibril-associated collagen (type IX), and network-forming collagen (type X) cause a spectrum of diseases of bone, cartilage, and blood vessels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Abnormal compartmentalization of cartilage matrix components in mice lacking collagen X: implications for function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

An endoplasmic reticulum storage disease causing congenital goiter with hypothyroidism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Amino acid substitutions of conserved residues in the carboxyl-terminal domain of the alpha 1(X) chain of type X collagen occur in two unrelated families with metaphyseal chondrodysplasia type Schmid

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

A type X collagen mutation causes Schmid metaphyseal chondrodysplasia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757901

Phenotypic and biochemical consequences of collagen X mutations in mice and humans

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000691

Mutations of COL10A1 in Schmid metaphyseal chondrodysplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000691

Misfolding of collagen X chains harboring Schmid metaphyseal chondrodysplasia mutations results in aberrant disulfide bond formation, intracellular retention, and activation of the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000691

Growth of the laboratory mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000691

Lineage tracing using matrilin-1 gene expression reveals that articular chondrocytes exist as the joint interzone forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1000691

21 January 2018

Integrin Gene Targeting

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19834559

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Normal long bone growth and development in type X collagen-null mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19834559

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Col4a1 mutation causes endoplasmic reticulum stress and genetically modifiable ocular dysgenesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19834559

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1000691

1 reference

27 July 2017

1 reference

27 July 2017

1 reference