A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway (Q33523813)

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English	A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway	scientific article

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scholarly article

1 reference

Europe PubMed Central

27 July 2017

A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway (English)

1 reference

Europe PubMed Central

27 July 2017

Derek B Sant'Angelo

4

object named as

Derek B Sant'Angelo

1 reference

Europe PubMed Central

27 July 2017

author name string

Damian Kovalovsky

1

1 reference

Europe PubMed Central

27 July 2017

Mark Pezzano

2

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Europe PubMed Central

27 July 2017

Benjamin D Ortiz

3

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Europe PubMed Central

27 July 2017

language of work or name

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publication date

13 January 2010

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Europe PubMed Central

27 July 2017

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Europe PubMed Central

27 July 2017

5

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Europe PubMed Central

27 July 2017

1

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Europe PubMed Central

27 July 2017

e8675

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Europe PubMed Central

27 July 2017

copyright license

Creative Commons Attribution 4.0 International

13 January 2010

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April 2022 Public Data File from Crossref

copyright status

0 references

Identification of CD4(-)CD8(-) double-negative natural killer T cell precursors in the thymus

1 reference

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21 June 2018

Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

During negative selection, Nur77 family proteins translocate to mitochondria where they associate with Bcl-2 and expose its proapoptotic BH3 domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Lineage diversion of T cell receptor transgenic thymocytes revealed by lineage fate mapping.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Calcineurin sets the bandwidth for discrimination of signals during thymocyte development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

What do we know about the mechanisms of elimination of autoreactive T and B cells and what challenges remain

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Apoptosis during negative selection of autoreactive thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

A decade of AIRE.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

The molecular mechanisms that control function and death of effector CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

The E delta enhancer controls the generation of CD4- CD8- alphabetaTCR-expressing T cells that can give rise to different lineages of alphabeta T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

The timing of TCR alpha expression critically influences T cell development and selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Induction of T cell development and establishment of T cell competence from embryonic stem cells differentiated in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Absence of Programmed Death Receptor 1 Alters Thymic Development and Enhances Generation of CD4/CD8 Double-Negative TCR-Transgenic T Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Rapid induction of medullary thymocyte phenotypic maturation and egress inhibition by nanomolar sphingosine 1-phosphate receptor agonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Positive and negative selection of T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Costimulatory signals are required for induction of transcription factor Nur77 during negative selection of CD4(+)CD8(+) thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Unexpectedly complex regulation of CD4/CD8 coreceptor expression supports a revised model for CD4+CD8+ thymocyte differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

The alpha beta T cell receptor can replace the gamma delta receptor in the development of gamma delta lineage cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

The specificity and orientation of a TCR to its peptide-MHC class II ligands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Control points in early T-cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

T cell receptor gene recombination patterns and mechanisms: cell death, rescue, and T cell production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

A murine early thymocyte developmental sequence is marked by transient expression of the interleukin 2 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

21 June 2018

Immature CD4+CD8+ thymocytes and mature T cells regulate Nur77 distinctly in response to TCR stimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

31 October 2018

Negative selection of the T-cell repertoire: where and when does it occur?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

31 October 2018

A role for TCR affinity in regulating naive T cell homeostasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

31 October 2018

A molecular map of T cell development.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

31 October 2018

Role of TCR specificity in CD4 versus CD8 lineage commitment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2800196

31 October 2018

Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20072628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of immature CD4+CD8−CD3− thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20072628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cassette vectors directing expression of T cell receptor genes in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20072628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The imprint of intrathymic self-peptides on the mature T cell receptor repertoire

1 reference

https://pubmed.ncbi.nlm.nih.gov/20072628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The TCRalpha locus control region specifies thymic, but not peripheral, patterns of TCRalpha gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20072628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional analysis of clonal deletion in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20072628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early TCR expression and aberrant T cell development in mice with endogenous prerearranged T cell receptor genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20072628

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0008675

1 reference

Europe PubMed Central

27 July 2017

2010PLoSO...5.8675K

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1 reference

Europe PubMed Central

27 July 2017

1 reference

Europe PubMed Central

27 July 2017

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