Multifunctional antioxidants for the treatment of age-related diseases (Q33524505)

27 July 2017

title

Multifunctional antioxidants for the treatment of age-related diseases (English)

1 reference

27 July 2017

Hongxia Jin

1

1 reference

27 July 2017

James Randazzo

series ordinal

2

1 reference

27 July 2017

Peng Zhang

series ordinal

3

1 reference

27 July 2017

Peter F Kador

series ordinal

4

1 reference

27 July 2017

language of work or name

English

0 references

publication date

1 February 2010

1 reference

Journal of Medicinal Chemistry

27 July 2017

published in

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27 July 2017

volume

53

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27 July 2017

issue

3

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27 July 2017

page(s)

1117-1127

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Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis

27 July 2017

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21 June 2018

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21 June 2018

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Iron toxicity as a potential factor in AMD.

21 June 2018

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The oxidative hypothesis of senescence.

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21 June 2018

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21 June 2018

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21 June 2018

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alphaB-crystallin competes with Alzheimer's disease beta-amyloid peptide for peptide-peptide interactions and induces oxidation of Abeta-Met35

21 June 2018

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21 June 2018

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A review of antioxidants and Alzheimer's disease

21 June 2018

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Metals, toxicity and oxidative stress

21 June 2018

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21 June 2018

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21 June 2018

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Characterization of beta amyloid assemblies in drusen: the deposits associated with aging and age-related macular degeneration

21 June 2018

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Current status of metals as therapeutic targets in Alzheimer's disease

21 June 2018

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21 June 2018

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Serum iron, transferrin saturation, ferritin, and dietary data in age-related macular degeneration

21 June 2018

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21 June 2018

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21 June 2018

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ARPE-19, a human retinal pigment epithelial cell line with differentiated properties

21 June 2018

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Clioquinol neurotoxicity: an overview

21 June 2018

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Implication of protein oxidation in protein turnover, aging, and oxygen toxicity.

21 June 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826224

Amyloid-beta up-regulates complement factor B in retinal pigment epithelial cells through cytokines released from recruited macrophages/microglia: Another mechanism of complement activation in age-related macular degeneration

21 June 2018

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Regression of symptoms after selective iron chelation therapy in a case of neurodegeneration with brain iron accumulation.

31 October 2018

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Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: importance of antioxidant and cannabinoid receptor-independent properties

31 October 2018

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Iron induced oxidative damage as a potential factor in age-related macular degeneration: the Cogan Lecture

31 October 2018

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In vivo protection by the xanthate tricyclodecan-9-yl-xanthogenate against amyloid beta-peptide (1-42)-induced oxidative stress

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826224

L-carnitine and neuroprotection in the animal model of mitochondrial dysfunction

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826224

Macular degeneration in a patient with aceruloplasminemia, a disease associated with retinal iron overload

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826224

Metal ion-dependent effects of clioquinol on the fibril growth of an amyloid {beta} peptide

31 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826224

Clioquinol mediates copper uptake and counteracts copper efflux activities of the amyloid precursor protein of Alzheimer's disease

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826224

The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human beta-amyloid precursor protein transgenic mice

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826224

Aluminium, iron, zinc and copper influence the in vitro formation of amyloid fibrils of Abeta42 in a manner which may have consequences for metal chelation therapy in Alzheimer's disease.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826224

Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826224

Synthesis of feralex a novel aluminum/iron chelating compound

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826224

5-Pyrimidinols: novel chain-breaking antioxidants more effective than phenols

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826224

Protein-thiol mixed disulfides in human lens

31 October 2018

1 reference

12 December 2020

Mice transgenic for Alzheimer disease ?-amyloid develop lens cataracts that are rescued by antioxidant treatment

1 reference

12 December 2020

Cataractous changes in rat lens following cigarette smoke exposure is prevented by parenteral deferoxamine therapy

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12 December 2020

Redox availability of lens iron and copper: implications for HO* generation in cataract

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12 December 2020

Determination of binding stoichiometry by the continuous variation method: the Job plot

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12 December 2020

Identifiers

DOI

10.1021/JM901381J

1 reference

release_ujhd3wezzjatjpwhckbiuw25ru

27 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ujhd3wezzjatjpwhckbiuw25ru

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2826224

1 reference

27 July 2017

1 reference