Inhibitors of Leishmania GDP-mannose pyrophosphorylase identified by high-throughput screening of small-molecule chemical library (Q33531622)

27 July 2017

title

Inhibitors of Leishmania GDP-mannose pyrophosphorylase identified by high-throughput screening of small-molecule chemical library (English)

1 reference

GDP-mannose pyrophosphorylase

27 July 2017

main subject

1 reference

5 February 2019

Lukasz Kedzierski

10

0 references

author name string

Kurt Lackovic

1

1 reference

27 July 2017

John P Parisot

2

1 reference

27 July 2017

Nerida Sleebs

3

1 reference

27 July 2017

Jonathan B Baell

4

1 reference

27 July 2017

Laurent Debien

5

1 reference

27 July 2017

Keith G Watson

6

1 reference

27 July 2017

Joan M Curtis

7

1 reference

27 July 2017

Emanuela Handman

8

1 reference

27 July 2017

Ian P Street

9

1 reference

27 July 2017

language of work or name

English

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publication date

16 February 2010

1 reference

Antimicrobial Agents and Chemotherapy

27 July 2017

published in

1 reference

27 July 2017

volume

54

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27 July 2017

issue

5

1 reference

27 July 2017

page(s)

1712-1719

1 reference

New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays

27 July 2017

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21 June 2018

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21 June 2018

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21 June 2018

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Disruption of mannose activation in Leishmania mexicana: GDP-mannose pyrophosphorylase is required for virulence, but not for viability

21 June 2018

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21 June 2018

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Molecular basis of carbohydrate-deficient glycoprotein syndromes type I with normal phosphomannomutase activity

21 June 2018

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21 June 2018

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Uptake of Leishmania major amastigotes results in activation and interleukin 12 release from murine skin-derived dendritic cells: implications for the initiation of anti-Leishmania immunity

21 June 2018

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Crystal structure of phosphate binding protein labeled with a coumarin fluorophore, a probe for inorganic phosphate

21 June 2018

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Synthesis and anthelmintic activity of 3'-benzoylurea derivatives of 6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole

21 June 2018

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21 June 2018

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In vitro susceptibilities of Leishmania donovani promastigote and amastigote stages to antileishmanial reference drugs: practical relevance of stage-specific differences

31 October 2018

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31 October 2018

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31 October 2018

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Discovery of novel aminothiadiazole amides as selective EP(3) receptor antagonists.

31 October 2018

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Structure-based prediction of Mycobacterium tuberculosis shikimate kinase inhibitors by high-throughput virtual screening

31 October 2018

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31 October 2018

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Properties of GDP-mannose pyrophosphorylase, a critical enzyme and drug target in Leishmania mexicana

31 October 2018

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Structure of Leishmania mexicana Phosphomannomutase Highlights Similarities with Human Isoforms

31 October 2018

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31 October 2018

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12 December 2020

based on heuristic

In vitro maintenance of Leishmania amastigotes directly from lesions: advantages and limitations

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20160053

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.01634-09

1 reference

27 July 2017

1 reference

27 July 2017

1 reference