Telomerase enzyme activation and human cell immortalization (Q33533965)

27 July 2017

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title

Telomerase enzyme activation and human cell immortalization (English)

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27 July 2017

Meyerson M

1

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27 July 2017

1 December 1998

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27 July 2017

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27 July 2017

102-103

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27 July 2017

41-45

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Addition of telomere-associated HeT DNA sequences "heals" broken chromosome ends in Drosophila

27 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Structure and function of telomeres

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Telomere elongation in immortal human cells without detectable telomerase activity

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

A human telomeric protein

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

1 reference

7 January 2021

Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Telomerase activity in human ovarian carcinoma

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

The catalytic subunit of yeast telomerase

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

The RNA component of human telomerase

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Telomeres shorten during ageing of human fibroblasts

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

A mammalian telomerase-associated protein

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Human telomerase contains evolutionarily conserved catalytic and structural subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Telomere reduction in human colorectal carcinoma and with ageing

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

The serial cultivation of human diploid cell strains

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Specific association of human telomerase activity with immortal cells and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Expression of TERT in early premalignant lesions and a subset of cells in normal tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Reverse transcriptase motifs in the catalytic subunit of telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

A mutant with a defect in telomere elongation leads to senescence in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Severe growth defect in mouse cells lacking the telomerase RNA component.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Developmental and tissue-specific regulation of mouse telomerase and telomere length

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Human cell transformation by simian virus 40—A review

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

A survey of telomerase activity in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

TLC1: template RNA component of Saccharomyces cerevisiae telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Control of telomere length by the human telomeric protein TRF1

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

TRF2 Protects Human Telomeres from End-to-End Fusions

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https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0378-4274%2898%2900278-1

7 January 2021

10.1016/S0378-4274(98)00278-1

Identifiers

DOI

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27 July 2017

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PubMed ID

10022230