Molecular and kinetic determinants of local anaesthetic action on sodium channels (Q33537113)

27 July 2017

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title

Molecular and kinetic determinants of local anaesthetic action on sodium channels (English)

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27 July 2017

French RJ

1

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27 July 2017

Zamponi GW

series ordinal

2

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27 July 2017

Sierralta IE

series ordinal

3

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27 July 2017

publication date

1 November 1998

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27 July 2017

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27 July 2017

volume

100-101

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27 July 2017

page(s)

247-254

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External site for local anesthetic block of cardiac Na+ channels*1

27 July 2017

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A mu-conotoxin-insensitive Na+ channel mutant: possible localization of a binding site at the outer vestibule

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7 January 2021

Ultra-deep blockade of Na+ channels by a quaternary ammonium ion: catalysis by a transition-intermediate state?

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Time- and voltage-dependent interactions of antiarrhythmic drugs with cardiac sodium channels

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Asymmetry of the Acetylcholine Channel Revealed by Quaternary Anesthetics

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Batrachotoxin as a tool to study voltage-sensitive sodium channels of excitable membranes

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A mutation in segment IVS6 disrupts fast inactivation of sodium channels

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A critical role for transmembrane segment IVS6 of the sodium channel alpha subunit in fast inactivation

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Isochannels and blocking modes of voltage-dependent sodium channels

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pH-dependent binding of local anesthetics in single batrachotoxin-activated Na+ channels. Cocaine vs. quaternary compounds

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Cardiac sodium channels (hH1) are intrinsically more sensitive to block by lidocaine than are skeletal muscle (mu 1) channels

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Molecular determinants of drug access to the receptor site for antiarrhythmic drugs in the cardiac Na+ channel

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7 January 2021

Molecular determinants of state-dependent block of Na+ channels by local anesthetics

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Common molecular determinants of local anesthetic, antiarrhythmic, and anticonvulsant block of voltage-gated Na+ channels

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Multiple open channel states revealed by lidocaine and QX-314 on rat brain voltage-dependent sodium channels

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Blocking mechanisms of batrachotoxin-activated Na channels in artificial bilayers

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Differences in steady-state inactivation between Na channel isoforms affect local anesthetic binding affinity

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Na channel activation gate modulates slow recovery from use-dependent block by local anesthetics in squid giant axons

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7 January 2021

Fast lidocaine block of cardiac and skeletal muscle sodium channels: one site with two routes of access.

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7 January 2021

State-dependent block underlies the tissue specificity of lidocaine action on batrachotoxin-activated cardiac sodium channels

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7 January 2021

Dual actions of procainamide on batrachotoxin-activated sodium channels: open channel block and prevention of inactivation

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7 January 2021

Beta subunit coexpression and the alpha1 subunit domain I-II linker affect piperidine block of neuronal calcium channels.

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7 January 2021

Dissecting lidocaine action: diethylamide and phenol mimic separate modes of lidocaine block of sodium channels from heart and skeletal muscle

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7 January 2021

Open-channel block by internally applied amines inhibits activation gate closure in batrachotoxin-activated sodium channels

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7 January 2021

Amine blockers of the cytoplasmic mouth of sodium channels: a small structural change can abolish voltage dependence

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7 January 2021

10.1016/S0378-4274(98)00192-1

Identifiers

DOI

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27 July 2017

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