Prostaglandin E2 regulates the expression of connective tissue growth factor (CTGF/CCN2) in human osteoarthritic chondrocytes via the EP4 receptor (Q33537427)

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English	Prostaglandin E2 regulates the expression of connective tissue growth factor (CTGF/CCN2) in human osteoarthritic chondrocytes via the EP4 receptor	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

27 July 2017

Prostaglandin E2 regulates the expression of connective tissue growth factor (CTGF/CCN2) in human osteoarthritic chondrocytes via the EP4 receptor (English)

1 reference

Europe PubMed Central

27 July 2017

0 references

connective tissue

1 reference

based on heuristic

inferred from title

prostaglandin E2

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based on heuristic

inferred from title

1

object named as

Kayo Masuko

1 reference

Europe PubMed Central

27 July 2017

author name string

Minako Murata

2

1 reference

Europe PubMed Central

27 July 2017

Kazuo Yudoh

3

1 reference

Europe PubMed Central

27 July 2017

Hiroyuki Shimizu

4

1 reference

Europe PubMed Central

27 July 2017

Moroe Beppu

5

1 reference

Europe PubMed Central

27 July 2017

Hiroshi Nakamura

6

1 reference

Europe PubMed Central

27 July 2017

Tomohiro Kato

7

1 reference

Europe PubMed Central

27 July 2017

publication date

15 January 2010

1 reference

Europe PubMed Central

27 July 2017

BMC Research Notes

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Europe PubMed Central

27 July 2017

3

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Europe PubMed Central

27 July 2017

5

1 reference

Europe PubMed Central

27 July 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2826353/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

https://scigraph.springernature.com/pub.10.1186/1756-0500-3-5

0 references

Prostaglandin E2 and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

CCN family 2/connective tissue growth factor modulates BMP signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

CCN family 2/connective tissue growth factor (CCN2/CTGF) regulates the expression of Vegf through Hif-1alpha expression in a chondrocytic cell line, HCS-2/8, under hypoxic condition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Prostaglandin E2 exerts catabolic effects in osteoarthritis cartilage: evidence for signaling via the EP4 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Regulation and function of connective tissue growth factor/CCN2 in tissue repair, scarring and fibrosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Focal adhesion kinase/Src suppresses early chondrogenesis: central role of CCN2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Prostaglandin E receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

All in the CCN family: essential matricellular signaling modulators emerge from the bunker

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Collaborative action of M-CSF and CTGF/CCN2 in articular chondrocytes: possible regenerative roles in articular cartilage metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

PGE2 signal through EP2 promotes the growth of articular chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Activation of EP4 receptors contributes to prostaglandin E2-mediated stimulation of renal sensory nerves

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

CCN proteins: multifunctional signalling regulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Transcriptional induction of connective tissue growth factor/hypertrophic chondrocyte-specific 24 gene by dexamethasone in human chondrocytic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Role of CTGF/HCS24/ecogenin in skeletal growth control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Role of prostaglandin E(2) EP receptors and cAMP in the expression of connective tissue growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Identification of glycosylated 38-kDa connective tissue growth factor (IGFBP-related protein 2) and proteolytic fragments in human biological fluids, and up-regulation of IGFBP-rP2 expression by TGF-beta in Hs578T human breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

14 July 2018

PGE2 signal via EP2 receptors evoked by a selective agonist enhances regeneration of injured articular cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

31 October 2018

Rac1 signaling regulates CTGF/CCN2 gene expression via TGFbeta/Smad signaling in chondrocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

31 October 2018

Hypoxia upregulates the expression of angiopoietin-like-4 in human articular chondrocytes: role of angiopoietin-like-4 in the expression of matrix metalloproteinases and cartilage degradation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

31 October 2018

Simultaneous stimulation of EP2 and EP4 is essential to the effect of prostaglandin E2 in chondrocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

31 October 2018

Connective tissue growth factor and its regulation in the peritoneal cavity of peritoneal dialysis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2826353

31 October 2018

Regulation of connective tissue growth factor expression by prostaglandin E(2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20205862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CCN family 2/connective tissue growth factor (CCN2/CTGF) stimulates proliferation and differentiation of auricular chondrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20205862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and localization of connective tissue growth factor (CTGF/Hcs24/CCN2) in osteoarthritic cartilage

1 reference

https://pubmed.ncbi.nlm.nih.gov/20205862

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1756-0500-3-5

1 reference

Europe PubMed Central

27 July 2017

Dimensions Publication ID

1 reference

https://scigraph.springernature.com/pub.10.1186/1756-0500-3-5

9 September 2019

release_mzkbu32onjaytcmelvk2thadsi

1 reference

https://api.fatcat.wiki/v0/release/mzkbu32onjaytcmelvk2thadsi

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

27 July 2017

1 reference

Europe PubMed Central

27 July 2017

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