Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions. (Q33538646)

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11 November 2019

review article

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title

Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10066510%20AND%20SRC:MED&resulttype=core&format=json

host-parasite interaction

11 November 2019

main subject

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1

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11 November 2019

author name string

D R Brooks

series ordinal

2

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11 November 2019

G H Coombs

series ordinal

3

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11 November 2019

publication date

1 August 1998

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Current Opinion in Microbiology

11 November 2019

published in

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11 November 2019

volume

1

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11 November 2019

issue

4

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11 November 2019

page(s)

455-460

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The multiple cpb cysteine proteinase genes of Leishmania mexicana encode isoenzymes that differ in their stage regulation and substrate preferences.

11 November 2019

cites work

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Identification of new cysteine protease gene isoforms in Trypanosoma cruzi.

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Polymorphisms of the genes encoding cruzipain, the major cysteine proteinase of Trypanosoma cruzi, in the region encoding the C-terminal domain.

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A developmentally regulated cysteine proteinase gene of Leishmania mexicana

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Identification of two distinct cysteine proteinase genes of Leishmania pifanoi axenic amastigotes using the polymerase chain reaction.

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Molecular cloning, characterization and overexpression of two distinct cysteine protease cDNAs from Leishmania donovani chagasi

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Isolation of lmcpc, a gene encoding a Leishmania mexicana cathepsin-B-like cysteine proteinase.

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Leishmania major: comparison of the cathepsin L- and B-like cysteine protease genes with those of other trypanosomatids

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Characterisation of a Trypanosoma cruzi acidic 30 kDa cysteine protease

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Overexpression of cruzipain, the major cysteine proteinase of Trypanosoma cruzi, is associated with enhanced metacyclogenesis

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Null mutants for the lmcpa cysteine proteinase gene in Leishmania mexicana

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Cathepsin B-like cysteine proteinase-deficient mutants of Leishmania mexicana.

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Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

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Structure and functions of human kininogens

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Trypanosomatid cysteine protease activity may be enhanced by a kininogen-like moiety from host serum

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A cryptic protease activity from Trypanosoma cruzi revealed by preincubation with kininogen at low temperatures

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High-molecular-weight kininogen binds two molecules of cysteine proteinases with different rate constants

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7 January 2021

Alpha-2-macroglobulin binds to the surface of Trypanosoma cruzi

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Kininogenase activity by the major cysteinyl proteinase (cruzipain) from Trypanosoma cruzi

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7 January 2021

Plasma leakage induced in postcapillary venules by the major cysteine-proteinase from Trypanosoma cruzi and its modulation by H1-blocker mepyramine

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The cysteine protease of Trypanosoma cruzi as a model for antiparasite drug design

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Leishmania major: molecular modeling of cysteine proteases and prediction of new nonpeptide inhibitors

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Are bacterial proteinases pathogenic factors?

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Cytokines: making the right choice

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Transforming growth factor beta as a virulence mechanism for Leishmania braziliensis

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7 January 2021

Distribution of parasite cysteine proteinases in lesions of mice infected with Leishmania mexicana amastigotes

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7 January 2021

Proteases from Trypanosoma brucei brucei. Purification, characterisation and interactions with host regulatory molecules

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Inhibitory effects of human alpha 2-macroglobulin on Trypanosoma cruzi epimastigote proteinases

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7 January 2021

Trypanosomiasis and trypanotolerance in cattle: a role for congopain?

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7 January 2021

Detection of cruzipain, the major cysteine proteinase from Trypanosoma cruzi and its C-terminal extension in biological fluids during experimental infection in mice

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7 January 2021

Exoantigens from trypanosoma cruzi contain cruzipain

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Human T cell responses against the major cysteine proteinase (cruzipain) of Trypanosoma cruzi: role of the multifunctional alpha 2- macroglobulin receptor in antigen presentation by monocytes

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7 January 2021

Antigen presentation by Leishmania mexicana-infected macrophages: activation of helper T cells specific for amastigote cysteine proteinases requires intracellular killing of the parasites.

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Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10066510%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

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