B cell-targeted therapies for systemic lupus erythematosus: an update on clinical trial data (Q33542751)

27 July 2017

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title

B cell-targeted therapies for systemic lupus erythematosus: an update on clinical trial data (English)

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systemic lupus erythematosus

27 July 2017

main subject

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author name string

R John Looney

series ordinal

1

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27 July 2017

publication date

1 March 2010

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27 July 2017

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27 July 2017

volume

70

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27 July 2017

issue

5

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27 July 2017

page(s)

529-540

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Maintenance of long-lived plasma cells and serological memory despite mature and memory B cell depletion during CD20 immunotherapy in mice.

27 July 2017

cites work

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Crossref

https://api.crossref.org/works/10.2165%2F11535420-000000000-00000

Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus

21 January 2018

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Crossref

https://api.crossref.org/works/10.2165%2F11535420-000000000-00000

Requirement of B cells for generating CD4+ T cell memory

21 January 2018

1 reference

12 December 2020

APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells

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12 December 2020

A role for BLyS in the activation of innate immune cells

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12 December 2020

BAFF AND APRIL: a tutorial on B cell survival

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12 December 2020

A new morphologic index for the evaluation of renal biopsies in lupus nephritis

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12 December 2020

Atacicept in patients with rheumatoid arthritis: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating, single- and repeated-dose study

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12 December 2020

The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIB randomized, double-blind, placebo-controlled, dose-ranging trial

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12 December 2020

A regulatory B cell subset with a unique CD1dhiCD5+ phenotype controls T cell-dependent inflammatory responses

1 reference

12 December 2020

Differential effects of epratuzumab on peripheral blood B cells of patients with systemic lupus erythematosus versus normal controls

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12 December 2020

Reduced B lymphocyte and immunoglobulin levels after atacicept treatment in patients with systemic lupus erythematosus: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating trial

1 reference

12 December 2020

The central and multiple roles of B cells in lupus pathogenesis

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12 December 2020

A retrospective seven-year analysis of the use of B cell depletion therapy in systemic lupus erythematosus at University College London Hospital: the first fifty patients

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12 December 2020

Novel evidence-based systemic lupus erythematosus responder index

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12 December 2020

A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice.

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12 December 2020

Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: the randomized, double-blind, phase II/III systemic lupus erythematosus evaluation of rituximab trial

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12 December 2020

Safety, pharmacokinetics and pharmacodynamics of atacicept in healthy volunteers

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12 December 2020

B-cell depletion with rituximab in relapsing-remitting multiple sclerosis

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12 December 2020

Depletion of B cells in murine lupus: efficacy and resistance

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12 December 2020

The cutaneous lupus erythematosus disease activity and severity index: Expansion for rheumatology and dermatology

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12 December 2020

Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks

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12 December 2020

Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy

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12 December 2020

Outcome of relapse in lupus nephritis: roles of reversal of renal fibrosis and response of inflammation to therapy.

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12 December 2020

A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus

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12 December 2020

The effects of rituximab on immunocompetency in patients with autoimmune disease

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12 December 2020

A phase II, randomized, double-blind, placebo-controlled, dose-ranging study of belimumab in patients with active systemic lupus erythematosus

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12 December 2020

Anticytokine therapy impacting on B cells in autoimmune diseases

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12 December 2020

Mycophenolate sodium for subacute cutaneous lupus erythematosus resistant to standard therapy

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12 December 2020

The cutaneous lupus erythematosus disease area and severity index: a responsive instrument to measure activity and damage in patients with cutaneous lupus erythematosus

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12 December 2020

BAFF blockade for systemic lupus erythematosus: will the promise be fulfilled?

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12 December 2020

Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression

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12 December 2020

Cracking the BAFF code.

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12 December 2020

Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis. A randomized, controlled trial

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12 December 2020

Therapeutic B cell depletion impairs adaptive and autoreactive CD4+ T cell activation in mice

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12 December 2020

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

1 reference

12 December 2020

Immunosuppressive therapy in lupus nephritis: the Euro-Lupus Nephritis Trial, a randomized trial of low-dose versus high-dose intravenous cyclophosphamide

1 reference

12 December 2020

Predictive power of the second renal biopsy in lupus nephritis: significance of macrophages

1 reference

12 December 2020

Maintenance of the plasma cell pool is independent of memory B cells

1 reference

12 December 2020

10.2165/11535420-000000000-00000

Identifiers

DOI

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Dimensions Publication ID

27 July 2017

1024642883

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