Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias (Q33544984)

27 July 2017

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title

Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias (English)

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27 July 2017

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West MJ

1

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27 July 2017

1 February 1999

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27 July 2017

Trends in Neurosciences

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27 July 2017

22

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27 July 2017

2

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27 July 2017

51-61

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Are you using neuronal densities, synaptic densities or neurochemical densities as your definitive data? There is a better way to go.

27 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

Reliability and validity of the physical disector method for estimating neuron number.

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7 January 2021

A review of recent advances in stereology for quantifying neural structure

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https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

Practical considerations for the use of the optical disector in estimating neuronal number.

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https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

Quantification without pontification: choosing a method for counting objects in sectioned tissues

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7 January 2021

The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

Unbiased stereological estimation of the total number of synapses in a brain region

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https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

A stereological study of dorsal root ganglion cells and nerve root fibers from rats treated with inorganic mercury

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https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

Neuronal cell loss in the CA3 subfield of the hippocampus following cortical contusion utilizing the optical disector method for cell counting.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

The volume of Purkinje cells decreases in the cerebellum of acrylamide-intoxicated rats, but no cells are lost

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

Absolute number and size of pigmented locus coeruleus neurons in young and aged individuals

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

Memory impaired aged rats: no loss of principal hippocampal and subicular neurons.

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7 January 2021

Chronic psychosocial stress does not affect the number of pyramidal neurons in tree shrew hippocampus.

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7 January 2021

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

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7 January 2021

Total number of neurons in the layers of the human entorhinal cortex.

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7 January 2021

Chronic nicotine treatment counteracts nigral cell loss induced by a partial mesodiencephalic hemitransection: an analysis of the total number and mean volume of neurons and glia in substantia nigra of the male rat

1 reference

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7 January 2021

Estimation of the number of somatostatin neurons in the striatum: an in situ hybridization study using the optical fractionator method

1 reference

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7 January 2021

The efficiency of systematic sampling in stereology and its prediction.

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7 January 2021

Estimation of nuclear population from microtome sections

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7 January 2021

A principle for counting tissue structures on random sections

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7 January 2021

The unbiased estimation of number and sizes of arbitrary particles using the disector

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

A consideration of neural counting methods

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

New stereological methods for counting neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

The absolute number of nerve cells in substantia nigra in normal subjects and in patients with Parkinson's disease estimated with an unbiased stereological method

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

How inaccurate is the Abercrombie correction factor for cell counts?

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

Spatial, temporal and numeric analysis of Alzheimer changes in the nucleus coeruleus.

1 reference

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7 January 2021

Unbiased estimation of human body composition by the Cavalieri method using magnetic resonance imaging.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

Single section and disector counts in evaluating neuronal loss from the substantia nigra in patients with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease.

1 reference

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7 January 2021

Stereology: a practical primer for neuropathology

1 reference

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7 January 2021

Stereology: the fast lane between neuroanatomy and brain function--or still only a tightrope?

1 reference

https://api.crossref.org/works/10.1016%2FS0166-2236%2898%2901362-9

7 January 2021

10.1016/S0166-2236(98)01362-9

Identifiers

DOI

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27 July 2017

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PubMed ID

10092043