Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis (Q33553744)

28 July 2017

Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis (English)

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28 July 2017

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Anne S Henkel

1

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28 July 2017

Marc S Elias

series ordinal

2

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28 July 2017

Richard M Green

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3

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28 July 2017

language of work or name

English

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publication date

17 September 2009

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Journal of Biological Chemistry

28 July 2017

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28 July 2017

284

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28 July 2017

46

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28 July 2017

31807-31816

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Effects of triglyceride on ER stress and insulin resistance

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Role of S-adenosyl-L-methionine in liver health and injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Endoplasmic reticulum stress signaling in disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Levels of homocysteine are increased in metabolic syndrome patients but are not associated with an increased cardiovascular risk, in contrast to patients without the metabolic syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Homocysteine lowering and cardiovascular events after acute myocardial infarction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Homocysteine lowering with folic acid and B vitamins in vascular disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

The unfolded protein response: a stress signaling pathway critical for health and disease.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Signaling the unfolded protein response from the endoplasmic reticulum.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Liver injury in alpha1-antitrypsin deficiency: an aggregated protein induces mitochondrial injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

A central role for JNK in obesity and insulin resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Homocysteine stimulates the production and secretion of cholesterol in hepatic cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Characterization of the stress-inducing effects of homocysteine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Hepatic content of S-adenosylmethionine, S-adenosylhomocysteine and glutathione in rats receiving treatments modulating methyl donor availability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Elevated plasma homocysteine concentrations as a predictor of steatohepatitis in patients with non-alcoholic fatty liver disease

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.017970

Cystathionine beta synthase deficiency promotes oxidative stress, fibrosis, and steatosis in mice liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.017970

Serum folate and homocysteine levels in obese females with non-alcoholic fatty liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.017970

Endoplasmic reticulum stress, hepatocyte CD1d and NKT cell abnormalities in murine fatty livers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.017970

Increased hepatic expression is a major determinant of serum alanine aminotransferase elevation in mice with nonalcoholic steatohepatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.017970

Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.017970

S-adenosylmethionine and its metabolite induce apoptosis in HepG2 cells: Role of protein phosphatase 1 and Bcl-x(S).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.017970

Mice heterozygous for the Mdr2 gene demonstrate decreased PEMT activity and diminished steatohepatitis on the MCD diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.017970

Reversed-phase high-performance liquid chromatography procedure for the simultaneous determination of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine in mouse liver and the effect of methionine on their concentrations

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2797251

Homocystinuria due to cystathionine synthase deficiency: enzymatic and ultrastructural studies

31 October 2018

1 reference

12 December 2020

Hepatic DNA methylation and liver tumor formation in male C3H mice fed methionine- and choline-deficient diets

1 reference

12 December 2020

Hyperhomocysteinemia: an independent risk factor for vascular disease

1 reference

12 December 2020

Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis

1 reference

12 December 2020

Associations between serum insulin and homocysteine in a Swedish population-a potential link between the metabolic syndrome and hyperhomocysteinemia: the Skaraborg project

1 reference

12 December 2020

CCAAT/enhancing binding protein beta deletion in mice attenuates inflammation, endoplasmic reticulum stress, and lipid accumulation in diet-induced nonalcoholic steatohepatitis

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.017970

1 reference

28 July 2017

1 reference

28 July 2017

1 reference