Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes (Q33559796)

28 July 2017

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Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes (English)

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28 July 2017

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14

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28 July 2017

Marjo-Riitta Järvelin

26

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28 July 2017

42

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28 July 2017

43

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28 July 2017

Unnur Þorsteinsdóttir

45

Valgerdur Steinthorsdottir

Unnur Thorsteinsdottir

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44

Valgerdur Steinthorsdottir

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Aimo Ruokonen

25

Aimo Ruokonen

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Inês Barroso

55

Inês Barroso

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Johanna Kuusisto

33

Johanna Kuusisto

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Claudia Langenberg

3

Claudia Langenberg

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Thomas Illig

48

Thomas Illig

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Narisu Narisu

17

Narisu Narisu

1 reference

28 July 2017

8

Harald Grallert

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28 July 2017

7

Gudmar Thorleifsson

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28 July 2017

Anette P Gjesing

36

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Giuseppe Paolisso

Giuseppe Paolisso

11

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Oluf Borbye Pedersen

Oluf Pedersen

53

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Tim Frayling

Timothy M Frayling

59

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Amanda J Bennett

Amanda Bennett

23

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Michael N Weedon

Michael N Weedon

2

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Ewan Pearson

Ewan Pearson

27

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Mark McCarthy

Mark I McCarthy

58

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Nicholas J. Wareham

56

Nicholas J Wareham

1 reference

28 July 2017

49

Markku Laakso

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28 July 2017

54

Michael Boehnke

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28 July 2017

4

Anne U Jackson

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28 July 2017

9

Luigi Ferrucci

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28 July 2017

31

Heather M Stringham

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28 July 2017

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Lori L Bonnycastle

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5

Valeriya Lyssenko

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28 July 2017

52

Leif Groop

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28 July 2017

50

Kari Stefansson

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28 July 2017

Andrew Tym Hattersley

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Andrew T Hattersley

1 reference

28 July 2017

30

Stefan R Bornstein

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28 July 2017

47

Peter Schwarz

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28 July 2017

37

Charlotta Pisinger

1 reference

28 July 2017

29

Ele Ferrannini

1 reference

28 July 2017

38

Torsten Lauritzen

1 reference

28 July 2017

39

Annelli Sandbaek

1 reference

28 July 2017

18

Mario A Morken

1 reference

28 July 2017

21

Beverley Shields

1 reference

28 July 2017

13

Colin N A Palmer

1 reference

28 July 2017

32

Laura J Scott

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28 July 2017

28

Laura Pascoe

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28 July 2017

51

Andrew D Morris

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28 July 2017

10

Marcello Maggio

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28 July 2017

John R B Perry

1

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28 July 2017

Thomas Sparsø

6

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28 July 2017

Mark Walker

12

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28 July 2017

Elizabeth Young

15

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28 July 2017

Christian Herder

16

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28 July 2017

Katharine R Owen

20

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28 July 2017

Beatrice Knight

22

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28 July 2017

Christopher J Groves

24

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28 July 2017

Peter Nilsson

34

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28 July 2017

Malin Neptin

35

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28 July 2017

Mike Sampson

40

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28 July 2017

MAGIC

41

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28 July 2017

Torben Hansen

46

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28 July 2017

18 November 2009

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28 July 2017

Human Molecular Genetics

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28 July 2017

19

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28 July 2017

535-544

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28 July 2017

3

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Circulating beta-carotene levels and type 2 diabetes-cause or effect?

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Sex hormone-binding globulin and risk of type 2 diabetes in women and men

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Quantitative trait loci predicting circulating sex steroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3)

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Obesity and cancer: Mendelian randomization approach utilizing the FTO genotype

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Variants in MTNR1B influence fasting glucose levels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

A genome-wide association study identifies protein quantitative trait loci (pQTLs)

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Sex differences of endogenous sex hormones and risk of type 2 diabetes: a systematic review and meta-analysis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Role of endocytosis in cellular uptake of sex steroids.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Testosterone supplementation in men with type 2 diabetes, visceral obesity and partial androgen deficiency

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?*

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

A simple method for converting an odds ratio to effect size for use in meta-analysis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Do postmenopausal women with NIDDM have a reduced capacity to deposit and conserve lower-body fat?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Mechanisms behind insulin resistance in rat skeletal muscle after oophorectomy and additional testosterone treatment

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Hyperandrogenic anovulation (PCOS): a unique disorder of insulin action associated with an increased risk of non-insulin-dependent diabetes mellitus

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged D

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Variant in sex hormone-binding globulin gene and the risk of prostate cancer.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Insulin and leptin resistance with hyperleptinemia in mice lacking androgen receptor

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Sex hormone-binding globulin and insulin-like growth factor-binding protein-1 as indicators of metabolic syndrome, cardiovascular risk, and mortality in elderly men.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Polymorphisms associated with circulating sex hormone levels in postmenopausal women

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Partial androgen deficiency in aging type 2 diabetic men and its relationship to glycemic control

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

The associations of endogenous testosterone and sex hormone-binding globulin with glycosylated hemoglobin levels, in community dwelling men. The Tromsø Study

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

The biological variation of sex hormone-binding globulin in type 2 diabetes: implications for sex hormone-binding globulin as a surrogate marker of insulin resistance

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Do reproductive hormones modify insulin sensitivity and metabolism in older men? A randomized, placebo-controlled clinical trial of recombinant human chorionic gonadotropin

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Sex steroid hormones, upper body obesity, and insulin resistance.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Androgen therapy improves insulin sensitivity and decreases leptin level in healthy adult men with low plasma total testosterone: a 3-month randomized placebo-controlled trial

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Insulin regulates testosterone and sex hormone-binding globulin concentrations in adult normal weight and obese men.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

RANTES/CCL5 gene polymorphisms, serum concentrations, and incident type 2 diabetes: results from the MONICA/KORA Augsburg case–cohort study, 1984–2002

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Effect of macrophage migration inhibitory factor (MIF) gene variants and MIF serum concentrations on the risk of type 2 diabetes: results from the MONICA/KORA Augsburg Case–Cohort Study, 1984–2002

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

Two variants on chromosome 17 confer prostate cancer risk and the one in TCF2 protects against type 2 diabetes

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2798726

The effects of testosterone treatment on body composition and metabolism in middle-aged obese men

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19933169

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDP522

1 reference

28 July 2017

1 reference

28 July 2017

1 reference