Translational pharmacokinetic-pharmacodynamic modelling; application to cardiovascular safety data for PF-00821385, a novel HIV agent (Q33560293)

28 July 2017

title

Translational pharmacokinetic-pharmacodynamic modelling; application to cardiovascular safety data for PF-00821385, a novel HIV agent (English)

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28 July 2017

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John D Davis

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author name string

Grant Langdon

1

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28 July 2017

Lynn M McFadyen

3

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28 July 2017

Mark Dewhurst

4

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28 July 2017

Neil S Brunton

5

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28 July 2017

Jaiessh K Rawal

6

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28 July 2017

Piet H Van der Graaf

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28 July 2017

Neil Benson

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28 July 2017

language of work or name

English

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publication date

1 April 2010

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British Journal of Clinical Pharmacology

28 July 2017

published in

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28 July 2017

volume

69

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28 July 2017

issue

4

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28 July 2017

page(s)

336-345

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The genetic contribution to heart rate and heart rate variability in quiescent mice

28 July 2017

cites work

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21 June 2018

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21 June 2018

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The role of mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modelling in translational research of biologics

21 June 2018

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21 June 2018

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The electrocardiogram of the Beagle dog: reference values and effect of sex, genetic strain, body position and heart rate.

21 June 2018

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21 June 2018

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A pharmacokinetic-pharmacodynamic model for the quantitative prediction of dofetilide clinical QT prolongation from human ether-a-go-go-related gene current inhibition data

21 June 2018

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21 June 2018

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A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding

21 June 2018

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A review of the properties of spiradoline: a potent and selective kappa-opioid receptor agonist.

21 June 2018

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In vivo measurement of QT prolongation, dispersion and arrhythmogenesis: application to the preclinical cardiovascular safety pharmacology of a new chemical entity

21 June 2018

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Use of allometry in predicting anatomical and physiological parameters of mammals

21 June 2018

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Methods of collecting and evaluating non-clinical cardiac electrophysiology data in the pharmaceutical industry: results of an international survey

21 June 2018

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Spectral analysis of circadian rhythms in heart rate variability of dogs

21 June 2018

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Influence of asimadoline, a new kappa-opioid receptor agonist, on tubular water absorption and vasopressin secretion in man.

21 June 2018

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A pharmacokinetic-pharmacodynamic disease model to predict in vivo antiviral activity of maraviroc

21 June 2018

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Effects of Age on the Pharmacokinetics and Pharmacodynamics of Cardiovascular Drugs: Application of Concentration-Effect Modeling. 3. Trimazosin.

31 October 2018

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gp120: Biologic aspects of structural features

31 October 2018

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A fusion inhibitor (FP-21399) for the treatment of human immunodeficiency virus infection: a phase I study

31 October 2018

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Comparison of the water diuretic activity of kappa receptor agonists and a vasopressin receptor antagonist in dogs

31 October 2018

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Effect of autonomic nervous function on QT interval in dogs

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The Effects of Age on the Pharmacokinetics and Pharmacodynamics of Cardiovascular Drugs: Application of Concentration-Effect Modeling. 1. Tolmesoxide

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The Effects of Age on the Pharmacokinetics and Pharmacodynamics of Cardiovascular Drugs: Application of Concentration-Effect Modeling. 2. Acebutolol

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12 December 2020

10.1111/J.1365-2125.2009.03594.X

Identifiers

DOI

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28 July 2017

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28 July 2017

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