Computational study of the resistance shown by the subtype B/HIV-1 protease to currently known inhibitors (Q33563075)

28 July 2017

title

Computational study of the resistance shown by the subtype B/HIV-1 protease to currently known inhibitors (English)

1 reference

28 July 2017

Alessandro Genoni

1

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Giulia Morra

object named as

Giulia Morra

series ordinal

2

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Giorgio Colombo

object named as

Giorgio Colombo

series ordinal

4

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author name string

Kenneth M Merz

series ordinal

3

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28 July 2017

language of work or name

English

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publication date

1 May 2010

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28 July 2017

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28 July 2017

volume

49

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28 July 2017

issue

19

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28 July 2017

page(s)

4283-4295

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Predicting interaction sites from the energetics of isolated proteins: a new approach to epitope mapping.

28 July 2017

cites work

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14 July 2018

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14 July 2018

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Solution structure of HIV-1 protease flaps probed by comparison of molecular dynamics simulation ensembles and EPR experiments

14 July 2018

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Clinical phase 1 testing of the safety and immunogenicity of an epitope-based DNA vaccine in human immunodeficiency virus type 1-infected subjects receiving highly active antiretroviral therapy

14 July 2018

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Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Targeting structural flexibility in HIV-1 protease inhibitor binding

14 July 2018

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14 July 2018

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14 July 2018

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Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir

14 July 2018

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14 July 2018

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14 July 2018

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The changing landscape of protein allostery

14 July 2018

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HIV-1 protease flaps spontaneously open and reclose in molecular dynamics simulations

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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HIV-1 protease molecular dynamics of a wild-type and of the V82F/I84V mutant: possible contributions to drug resistance and a potential new target site for drugs

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease

14 July 2018

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14 July 2018

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Counteracting HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with XV638 and SD146, cyclic urea amides with broad specificities

14 July 2018

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HIV-1: fifteen proteins and an RNA

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Inhibitors of HIV-1 protease: a major success of structure-assisted drug design

14 July 2018

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Molecular basis of resistance to HIV-1 protease inhibition: a plausible hypothesis.

14 July 2018

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14 July 2018

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14 July 2018

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Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease

14 July 2018

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14 July 2018

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14 July 2018

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Structural mechanisms of HIV drug resistance

14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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Dimer disruption and monomer sequestration by alkyl tripeptides are successful strategies for inhibiting wild-type and multidrug-resistant mutated HIV-1 proteases

31 October 2018

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Mapping of two networks of residues that exhibit structural and dynamical changes upon binding in a PDZ domain protein

31 October 2018

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31 October 2018

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31 October 2018

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31 October 2018

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31 October 2018

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31 October 2018

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31 October 2018

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31 October 2018

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12 December 2020

Dynamics of ligand binding to myoglobin

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12 December 2020

The essential dynamics of thermolysin: Confirmation of the hinge-bending motion and comparison of simulations in vacuum and water

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Thermodynamic Basis of Resistance to HIV-1 Protease Inhibition: Calorimetric Analysis of the V82F/I84V Active Site Resistant Mutant†

1 reference

12 December 2020

Identifiers

DOI

10.1021/BI100569U

1 reference

28 July 2017

1 reference

28 July 2017

1 reference