Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate (Q33576702)

28 July 2017

Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate (English)

1 reference

28 July 2017

1

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Oleg A Igoshin

series ordinal

4

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Berthold Gottgens

series ordinal

3

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author name string

Aileen M Smith

series ordinal

2

1 reference

28 July 2017

6 May 2010

1 reference

PLOS Computational Biology

28 July 2017

1 reference

28 July 2017

6

1 reference

28 July 2017

5

1 reference

28 July 2017

e1000771

1 reference

Creative Commons Attribution 4.0 International

28 July 2017

start time

6 May 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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The transcriptional program controlled by the stem cell leukemia gene Scl/Tal1 during early embryonic hematopoietic development.

14 July 2018

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Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors

14 July 2018

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Global protein stability profiling in mammalian cells

14 July 2018

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Transcriptional regulatory networks in haematopoiesis

14 July 2018

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Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code

14 July 2018

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A novel mode of enhancer evolution: the Tal1 stem cell enhancer recruited a MIR element to specifically boost its activity

14 July 2018

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Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

14 July 2018

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Chromatin decouples promoter threshold from dynamic range

14 July 2018

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Hematopoiesis: an evolving paradigm for stem cell biology

14 July 2018

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Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver

14 July 2018

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Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells

14 July 2018

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Ab initio thermodynamic modeling of distal multisite transcription regulation

14 July 2018

1 reference

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Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

14 July 2018

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The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity

14 July 2018

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Evidence for diversity in transcriptional profiles of single hematopoietic stem cells

14 July 2018

1 reference

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Transcriptional dynamics of the embryonic stem cell switch

14 July 2018

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Regulatory dynamics of synthetic gene networks with positive feedback

14 July 2018

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Core transcriptional regulatory circuitry in human embryonic stem cells

14 July 2018

1 reference

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An Oct-1 binding site mediates activation of the gata2 promoter by BMP signaling

14 July 2018

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Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis

14 July 2018

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Transcriptional regulation by the numbers: applications

14 July 2018

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Transcriptional regulation by the numbers: models.

14 July 2018

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RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells

14 July 2018

1 reference

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Rapid spontaneous accessibility of nucleosomal DNA.

14 July 2018

1 reference

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SCL is required for normal function of short-term repopulating hematopoietic stem cells

14 July 2018

1 reference

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Random Boolean network models and the yeast transcriptional network

14 July 2018

1 reference

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GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling

14 July 2018

1 reference

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Notch1 but Not Notch2 Is Essential for Generating Hematopoietic Stem Cells from Endothelial Cells

14 July 2018

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On schemes of combinatorial transcription logic

14 July 2018

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Network motifs: simple building blocks of complex networks

14 July 2018

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GATA-2 and GATA-2/ER display opposing activities in the development and differentiation of blood progenitors

14 July 2018

1 reference

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Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors.

14 July 2018

1 reference

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Phosphorylation by mitogen-activated protein kinase mediates the hypoxia-induced turnover of the TAL1/SCL transcription factor in endothelial cells

14 July 2018

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Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor

14 July 2018

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A globin enhancer acts by increasing the proportion of erythrocytes expressing a linked transgene.

14 July 2018

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The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse

14 July 2018

1 reference

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Heterochromatin effects on the frequency and duration of LCR-mediated gene transcription.

14 July 2018

1 reference

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An early haematopoietic defect in mice lacking the transcription factor GATA-2

14 July 2018

1 reference

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Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865510

Enhancers increase the probability but not the level of gene expression

14 July 2018

1 reference

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Robustness and fragility of Boolean models for genetic regulatory networks.

14 July 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PCBI.1000771

Multilineage transcriptional priming and determination of alternate hematopoietic cell fates.

21 January 2018

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Genome-wide identification of cis-regulatory sequences controlling blood and endothelial development.

21 January 2018

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GATA2 functions at multiple steps in hemangioblast development and differentiation.

21 January 2018

1 reference

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Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20463872

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The OR control system of bacteriophage lambda. A physical-chemical model for gene regulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20463872

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanism of protein access to specific DNA sequences in chromatin: a dynamic equilibrium model for gene regulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20463872

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PCBI.1000771

1 reference

journals/ploscb/NarulaSGI10

28 July 2017

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

28 July 2017

1 reference

PubMed ID

20463872