The antifungal drug voriconazole is an efficient inhibitor of brain cholesterol 24S-hydroxylase in vitro and in vivo (Q33577839)

28 July 2017

The antifungal drug voriconazole is an efficient inhibitor of brain cholesterol 24S-hydroxylase in vitro and in vivo (English)

1 reference

28 July 2017

1 reference

Irina A Pikuleva

9

0 references

Olof Beck

object named as

Olof Beck

3

0 references

Ingemar Björkhem

object named as

Ingemar Björkhem

8

0 references

author name string

Marjan Shafaati

1

1 reference

28 July 2017

Natalia Mast

2

1 reference

28 July 2017

Rima Nayef

4

1 reference

28 July 2017

Gun Young Heo

5

1 reference

28 July 2017

Linda Björkhem-Bergman

6

1 reference

28 July 2017

Dieter Lütjohann

7

1 reference

28 July 2017

language of work or name

1 reference

27 May 2009

1 reference

Journal of Lipid Research

28 July 2017

1 reference

28 July 2017

51

1 reference

28 July 2017

2

1 reference

28 July 2017

318-323

1 reference

Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

The effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Cholesterol-24S-hydroxylase (CYP46A1) is specifically expressed in neurons of the neural retina

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1): marked insensitivity toward different regulatory axes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Expression of human cytochrome P450 46A1 in Escherichia coli: effects of N- and C-terminal modifications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Differential expression of cholesterol hydroxylases in Alzheimer's disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

A simple method for the isolation and purification of total lipides from animal tissues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Neurosteroid metabolism in the human brain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Putative helix F contributes to regioselectivity of hydroxylation in mitochondrial cytochrome P450 27A1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Importance of a novel oxidative mechanism for elimination of brain cholesterol. Turnover of cholesterol and 24(S)-hydroxycholesterol in rat brain as measured with 18O2 techniques in vivo and in vitro.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Crystal structures of metyrapone- and phenylimidazole-inhibited complexes of cytochrome P-450cam

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Phospholipids modify substrate binding and enzyme activity of human cytochrome P450 27A1.

21 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1194%2FJLR.M900174-JLR200

Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1194%2FJLR.M900174-JLR200

Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1194%2FJLR.M900174-JLR200

Preparation of lipide extracts from brain tissue.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803233

Determination of serum levels of unesterified lathosterol by isotope dilution-mass spectrometry

10 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19474457

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Spectroscopic investigations of ferric cytochrome P-450-CAM ligand complexes. Identification of the ligand trans to cysteinate in the native enzyme

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19474457

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1194/JLR.M900174-JLR200

1 reference

28 July 2017

1 reference

28 July 2017

1 reference