A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome (Q33579912)

28 July 2017

A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome (English)

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28 July 2017

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Luke R Holmes

4

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Jacqueline Boultwood

object named as

Jacqueline Boultwood

13

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Andrew N. J. McKenzie

14

object named as

Andrew N J McKenzie

1 reference

28 July 2017

Jillian L Barlow

1

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28 July 2017

Lesley F Drynan

2

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28 July 2017

Duncan R Hewett

3

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28 July 2017

Silvia Lorenzo-Abalde

5

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28 July 2017

Alison L Lane

6

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28 July 2017

Helen E Jolin

7

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28 July 2017

Richard Pannell

8

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28 July 2017

Angela J Middleton

9

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28 July 2017

See Heng Wong

10

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28 July 2017

Alan J Warren

11

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28 July 2017

James S Wainscoat

12

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28 July 2017

language of work or name

English

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publication date

22 November 2009

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28 July 2017

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28 July 2017

16

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28 July 2017

1

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28 July 2017

59-66

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https://scigraph.springernature.com/pub.10.1038/nm.2063

28 July 2017

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cites work

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Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction

21 June 2018

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p53 family in development

21 June 2018

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Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects

21 June 2018

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Haploinsufficiency of RPS14 in 5q- syndrome is associated with deregulation of ribosomal- and translation-related genes

21 June 2018

1 reference

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Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function.

21 June 2018

1 reference

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Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

21 June 2018

1 reference

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Inherited aplastic anaemias/bone marrow failure syndromes

21 June 2018

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Common deleted genes in the 5q- syndrome: thrombocytopenia and reduced erythroid colony formation in SPARC null mice

21 June 2018

1 reference

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The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast

21 June 2018

1 reference

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CHD5 is a tumor suppressor at human 1p36

21 June 2018

1 reference

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Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia

21 June 2018

1 reference

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Nuclear translocation of the calcium-binding protein ALG-2 induced by the RNA-binding protein RBM22

21 June 2018

1 reference

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Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion

21 June 2018

1 reference

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Ribosomal protein S6 gene haploinsufficiency is associated with activation of a p53-dependent checkpoint during gastrulation

21 June 2018

1 reference

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Tcof1/Treacle is required for neural crest cell formation and proliferation deficiencies that cause craniofacial abnormalities

21 June 2018

1 reference

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Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function

21 June 2018

1 reference

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Differential roles of microtubule assembly and sliding in proplatelet formation by megakaryocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function

21 June 2018

1 reference

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SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

21 June 2018

1 reference

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The Treacher Collins syndrome (TCOF1) gene product is involved in pre-rRNA methylation

21 June 2018

1 reference

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Aberrant and alternative splicing in cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

The Treacher Collins syndrome (TCOF1) gene product is involved in ribosomal DNA gene transcription by interacting with upstream binding factor

21 June 2018

1 reference

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Mutagenic insertion and chromosome engineering resource (MICER).

21 June 2018

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The carboxy-terminal extension of yeast ribosomal protein S14 is necessary for maturation of 43S preribosomes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Synaptopodin-deficient mice lack a spine apparatus and show deficits in synaptic plasticity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

The World Health Organization (WHO) classification of the myeloid neoplasms

21 June 2018

1 reference

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Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells

21 June 2018

1 reference

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NID67, a small putative membrane protein, is preferentially induced by NGF in PC12 pheochromocytoma cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

SPARC, a matricellular protein: at the crossroads of cell-matrix

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Rapid generation of nested chromosomal deletions on mouse chromosome 2.

21 June 2018

1 reference

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Genomic interval engineering of mice identifies a novel modulator of triglyceride production

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Selective isolation of cosmid clones by homologous recombination in Escherichia coli

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Distinct haematological disorder with deletion of long arm of no. 5 chromosome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Ribosomal protein S19 deficiency in zebrafish leads to developmental abnormalities and defective erythropoiesis through activation of p53 protein family

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Increased levels of apoptosis in the prefusion neural folds underlie the craniofacial disorder, Treacher Collins syndrome.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2803774

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

31 October 2018

1 reference

12 December 2020

Narrowing and genomic annotation of the commonly deleted region of the 5q- syndrome

1 reference

12 December 2020

Engineering de novo reciprocal chromosomal translocations associated with Mll to replicate primary events of human cancer

1 reference

12 December 2020

Molecular Mapping of Uncharacteristically Small 5q Deletions in Two Patients with the 5q- Syndrome: Delineation of the Critical Region on 5q and Identification of a 5q- Breakpoint

1 reference

12 December 2020

Diamond-Blackfan anemia. Natural history and sequelae of treatment

1 reference

12 December 2020

Gene expression profiling of CD34+cells in patients with the 5q− syndrome

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.2063

1 reference

28 July 2017

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28 July 2017

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