Bioinformatic clonality analysis of next-generation sequencing-derived viral vector integration sites (Q33586934)

28 July 2017

title

Bioinformatic clonality analysis of next-generation sequencing-derived viral vector integration sites (English)

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28 July 2017

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11

Christof von Kalle

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Manfred Schmidt

12

object named as

Manfred Schmidt

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28 July 2017

7

Nathalie Cartier

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28 July 2017

Anne Arens

1

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28 July 2017

Jens-Uwe Appelt

2

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28 July 2017

Cynthia C Bartholomae

3

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28 July 2017

Richard Gabriel

4

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28 July 2017

Anna Paruzynski

5

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28 July 2017

Derek Gustafson

6

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28 July 2017

Patrick Aubourg

8

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28 July 2017

Annette Deichmann

9

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28 July 2017

Hanno Glimm

10

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28 July 2017

publication date

1 April 2012

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Human gene therapy methods

28 July 2017

published in

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28 July 2017

volume

23

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28 July 2017

issue

2

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28 July 2017

page(s)

111-118

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Analyzing the number of common integration sites of viral vectors--new methods and computer programs

28 July 2017

cites work

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing

21 June 2018

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Efficacy of gene therapy for X-linked severe combined immunodeficiency

21 June 2018

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Genomic instability and myelodysplasia with monosomy 7 consequent to EVI1 activation after gene therapy for chronic granulomatous disease

21 June 2018

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Hematopoietic stem cell gene therapy with a lentiviral vector in X-linked adrenoleukodystrophy

21 June 2018

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Restoration of NET formation by gene therapy in CGD controls aspergillosis

21 June 2018

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NCBI Reference Sequences: current status, policy and new initiatives

21 June 2018

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Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

21 June 2018

1 reference

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Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1

21 June 2018

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Transposons in C. elegans

21 June 2018

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Real-time definition of non-randomness in the distribution of genomic events

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015219

Detecting statistically significant common insertion sites in retroviral insertional mutagenesis screens

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015219

Sequencing and analysis of Neanderthal genomic DNA

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015219

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015219

Genome sequencing in microfabricated high-density picolitre reactors

21 June 2018

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Efficient marking of human cells with rapid but transient repopulating activity in autografted recipients

21 June 2018

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Clonal evidence for the transduction of CD34+ cells with lymphomyeloid differentiation potential and self-renewal capacity in the SCID-X1 gene therapy trial

21 June 2018

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Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

21 June 2018

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21 June 2018

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 June 2018

1 reference

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Transcription start regions in the human genome are favored targets for MLV integration

21 June 2018

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HIV-1 integration in the human genome favors active genes and local hotspots

21 June 2018

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Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

21 June 2018

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21 June 2018

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In vivo footprinting of a muscle specific enhancer by ligation mediated PCR.

21 June 2018

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Novel use of polymerase chain reaction to amplify cellular DNA adjacent to an integrated provirus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015219

Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015219

Comprehensive genomic access to vector integration in clinical gene therapy

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015219

QuickMap: a public tool for large-scale gene therapy vector insertion site mapping and analysis

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015219

Gene therapy for immunodeficiency due to adenosine deaminase deficiency.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015219

High-resolution insertion-site analysis by linear amplification-mediated PCR (LAM-PCR).

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015219

Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015219

Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015219

The return of clonal marking sheds new light on human hematopoietic stem cells

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22559057

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

New genes involved in cancer identified by retroviral tagging

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22559057

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Distinct types of tumor-initiating cells form human colon cancer tumors and metastases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22559057

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1089/HGTB.2011.219

1 reference

28 July 2017

1 reference

28 July 2017

1 reference