Phase 1 clinical trial of intratumoral reovirus infusion for the treatment of recurrent malignant gliomas in adults (Q33586985)

28 July 2017

title

Phase 1 clinical trial of intratumoral reovirus infusion for the treatment of recurrent malignant gliomas in adults (English)

1 reference

28 July 2017

main subject

phase I clinical trial

0 references

1 reference

Kimberly P Kicielinski

1

1 reference

28 July 2017

E Antonio Chiocca

2

1 reference

28 July 2017

John S Yu

3

1 reference

28 July 2017

George M Gill

4

1 reference

28 July 2017

Matt Coffey

5

1 reference

28 July 2017

James M Markert

6

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28 July 2017

publication date

20 February 2014

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28 July 2017

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28 July 2017

volume

22

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28 July 2017

issue

5

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28 July 2017

page(s)

1056-1062

1 reference

Anatomical differences determine distribution of adenovirus after convection-enhanced delivery to the rat brain

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Analysis of a simulation algorithm for direct brain drug delivery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Local convection-enhanced delivery of chemotherapeutic agent transiently opens blood-brain barrier and improves efficacy of systemic chemotherapy in intracranial xenograft tumor model.

28 July 2018

1 reference

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A comprehensive outlook on intracerebral therapy of malignant gliomas.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Proteolytic disassembly is a critical determinant for reovirus oncolysis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Mammalian reovirus, a nonfusogenic nonenveloped virus, forms size-selective pores in a model membrane.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Recent progress in the battle between oncolytic viruses and tumours

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Oncolytic reovirus against ovarian and colon cancer.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Reovirus therapy of tumors with activated Ras pathway

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Brain tumors: criteria of response and definition of recurrence

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Imaging of convection enhanced delivery of toxins in humans

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Distribution properties of lentiviral vectors administered into the striatum by convection-enhanced delivery

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Evaluation and Optimization of the Administration of Recombinant Adeno-Associated Viral Vectors (Serotypes 2/1, 2/2, 2/rh8, 2/9, and 2/rh10) by Convection-Enhanced Delivery to the Striatum

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Intravenous administration of Reolysin, a live replication competent RNA virus is safe in patients with advanced solid tumors

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

A phase I trial of intratumoral administration of reovirus in patients with histologically confirmed recurrent malignant gliomas.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Viruses in the treatment of malignant glioma.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Comparison of intratumoral bolus injection and convection-enhanced delivery of radiolabeled antitenascin monoclonal antibodies

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Surface properties, more than size, limiting convective distribution of virus-sized particles and viruses in the central nervous system

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Reovirus as an experimental therapeutic for brain and leptomeningeal metastases from breast cancer

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Reovirus prolongs survival and reduces the frequency of spinal and leptomeningeal metastases from medulloblastoma.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Reovirus as an oncolytic agent against experimental human malignant gliomas

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Virus assay methods: accuracy and validation

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4015229

Systemic reovirus therapy of metastatic cancer in immune-competent mice

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24553100

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An evaluation of site-specific immune responses directed against first-generation adenoviral vectors administered by convection-enhanced delivery

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24553100

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MT.2014.21

1 reference

28 July 2017

1 reference

28 July 2017

1 reference