Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia (Q33591760)

28 July 2017

Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia (English)

1 reference

28 July 2017

Philip H Jones

3

0 references

Benjamin Simons

object named as

Benjamin D Simons

series ordinal

4

0 references

Allon M Klein

series ordinal

1

object named as

Allon M Klein

1 reference

28 July 2017

Douglas E Brash

2

1 reference

PubMed ID

20018764

28 July 2017

language of work or name

English

0 references

publication date

15 December 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

1 reference

28 July 2017

107

1 reference

28 July 2017

1

1 reference

28 July 2017

270-275

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Preneoplastic lesion growth driven by the death of adjacent normal stem cells

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Mutations of Bacteria from Virus Sensitivity to Virus Resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Epidermal transit of replication-arrested, undifferentiated keratinocytes in UV-exposed XPC mice: an alternative to in situ apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Stem cells in the hair follicle bulge contribute to wound repair but not to homeostasis of the epidermis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Relationship between UV-induced mutant p53 patches and skin tumours, analysed by mutation spectra and by induction kinetics in various DNA-repair-deficient mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

UVB-induced apoptosis drives clonal expansion during skin tumor development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Escaping the stem cell compartment: sustained UVB exposure allows p53-mutant keratinocytes to colonize adjacent epidermal proliferating units without incurring additional mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Persistent p53 mutations in single cells from normal human skin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Early p53-positive foci as indicators of tumor risk in ultraviolet-exposed hairless mice: kinetics of induction, effects of DNA repair deficiency, and p53 heterozygosity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Differential role of transcription-coupled repair in UVB-induced G2 arrest and apoptosis in mouse epidermis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Impact of global genome repair versus transcription-coupled repair on ultraviolet carcinogenesis in hairless mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Progress of a half century in the study of the Luria-Delbrück distribution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Time course for early adaptive responses to ultraviolet B light in the epidermis of SKH-1 mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Signaling via beta1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Frequent clones of p53-mutated keratinocytes in normal human skin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Early p53 alterations in mouse skin carcinogenesis by UVB radiation: immunohistochemical detection of mutant p53 protein in clusters of preneoplastic epidermal cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

UV and skin cancer: specific p53 gene mutation in normal skin as a biologically relevant exposure measurement

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

The epidermal proliferative unit: the possible role of the central basal cell

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Pigmentary and cutaneous risk factors for non-melanocytic skin cancer--a case-control study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Mutation selection and the natural history of cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

The clonal evolution of tumor cell populations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

Mathematical models of age and ultraviolet effects on the incidence of skin cancer among whites in the United States

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2806764

p53 protects against skin cancer induction by UV-B radiation.

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909738107

Antigen-specific immunity does not mediate acute regression of UVB-induced p53-mutant clones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909738107

Distinct stem cell populations regenerate the follicle and interfollicular epidermis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909738107

Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in the epidermis of p53 and Bax knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909738107

Kinetics of cell division in epidermal maintenance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909738107

A single type of progenitor cell maintains normal epidermis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909738107

A generalized Luria-Delbrück model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909738107

Administration of green tea or caffeine enhances the disappearance of UVB-induced patches of mutant p53 positive epidermal cells in SKH-1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909738107

Sunburn and p53 in the onset of skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909738107

Relationship between Mitosis and the Ordered Structure of the Stratum Corneum in Mouse Epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0909738107

21 January 2018

Identifiers

DOI

10.1073/PNAS.0909738107

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference

PubMed ID

20018764