Contribution of light chain residues to high affinity binding in an HIV-1 antibody explored by combinatorial scanning mutagenesis (Q33592517)

28 July 2017

title

Contribution of light chain residues to high affinity binding in an HIV-1 antibody explored by combinatorial scanning mutagenesis (English)

1 reference

28 July 2017

Joseph S Harrison

2

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author name string

Gustavo F Da Silva

series ordinal

1

1 reference

28 July 2017

Jonathan R Lai

series ordinal

3

1 reference

28 July 2017

language of work or name

English

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publication date

1 July 2010

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28 July 2017

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28 July 2017

volume

49

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28 July 2017

issue

26

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28 July 2017

page(s)

5464-5472

1 reference

De novo selection of high-affinity antibodies from synthetic fab libraries displayed on phage as pIX fusion proteins

28 July 2017

cites work

1 reference

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Affinity maturation and characterization of a human monoclonal antibody against HIV-1 gp41

28 July 2018

1 reference

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HIV-1 and influenza antibodies: seeing antigens in new ways

28 July 2018

1 reference

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Antibody recognition of a highly conserved influenza virus epitope

28 July 2018

1 reference

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Interactions of HIV-1 inhibitory peptide T20 with the gp41 N-HR coiled coil

28 July 2018

1 reference

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Understanding mechanisms governing protein-protein interactions from synthetic binding interfaces

28 July 2018

1 reference

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Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Synthetic antibody libraries focused towards peptide ligands.

28 July 2018

1 reference

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Manufacturing immunity to disease in a test tube: the magic bullet realized

28 July 2018

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Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion

28 July 2018

1 reference

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Interdomain communication between the thiolation and thioesterase domains of EntF explored by combinatorial mutagenesis and selection

28 July 2018

1 reference

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A protein interaction surface in nonribosomal peptide synthesis mapped by combinatorial mutagenesis and selection

28 July 2018

1 reference

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A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope

28 July 2018

1 reference

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Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Molecular recognition by a binary code

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Unraveling hot spots in binding interfaces: progress and challenges

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Recombinant human antibody single chain variable fragments reactive with Candida albicans surface antigens

28 July 2018

1 reference

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Protein design of an HIV-1 entry inhibitor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Rapid mapping of protein functional epitopes by combinatorial alanine scanning

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Energetic analysis of an antigen/antibody interface: alanine scanning mutagenesis and double mutant cycles on the HyHEL-10/lysozyme interaction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

A mutational analysis of binding interactions in an antigen-antibody protein-protein complex

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Antibody-antigen interactions: contact analysis and binding site topography.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

A mutational analysis of the binding of two different proteins to the same antibody

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Antibody-antigen interactions: new structures and new conformational changes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

A hot spot of binding energy in a hormone-receptor interface

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Therapeutic antibodies: current state and future trends--is a paradigm change coming soon?

28 July 2018

1 reference

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Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Synthetic therapeutic antibodies.

30 October 2018

1 reference

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Localized protein interaction surfaces on the EntB carrier protein revealed by combinatorial mutagenesis and selection.

30 October 2018

1 reference

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Structural basis for HIV-1 neutralization by a gp41 fusion intermediate-directed antibody.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Identification of differences in the specificity-determining residues of antibodies that recognize antigens of different size: implications for the rational design of antibody repertoires.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

Synthetic human antibodies and a strategy for protein engineering

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911358

30 October 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20518570

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20518570

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/BI100293Q

1 reference

28 July 2017

1 reference

28 July 2017

1 reference