Absence of both IL-7 and IL-15 severely impairs the development of CD8 T cell response against Toxoplasma gondii (Q33592970)

28 July 2017

title

Absence of both IL-7 and IL-15 severely impairs the development of CD8 T cell response against Toxoplasma gondii (English)

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28 July 2017

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Rajarshi Bhadra

1

1 reference

28 July 2017

Hongbing Guan

series ordinal

2

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28 July 2017

Imtiaz A Khan

series ordinal

3

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28 July 2017

language of work or name

English

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publication date

26 May 2010

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28 July 2017

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28 July 2017

volume

5

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28 July 2017

issue

5

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28 July 2017

page(s)

e10842

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Creative Commons Attribution 4.0 International

28 July 2017

copyright license

start time

26 May 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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21 June 2018

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21 June 2018

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21 June 2018

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Expression of IL-7 receptor alpha is necessary but not sufficient for the formation of memory CD8 T cells during viral infection

21 June 2018

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Cutting edge: IL-7-independent regulation of IL-7 receptor alpha expression and memory CD8 T cell development

21 June 2018

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Lack of IL-15 results in the suboptimal priming of CD4+ T cell response against an intracellular parasite

21 June 2018

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Diverse functions of IL-2, IL-15, and IL-7 in lymphoid homeostasis

21 June 2018

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IL-7 promotes T cell proliferation through destabilization of p27Kip1.

21 June 2018

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IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria parasites.

21 June 2018

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21 June 2018

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Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

21 June 2018

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21 June 2018

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IL-2 negatively regulates IL-7 receptor alpha chain expression in activated T lymphocytes

21 June 2018

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Multiple choices: regulation of memory CD8 T cell generation and homeostasis by interleukin (IL)-7 and IL-15

21 June 2018

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Interleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells

21 June 2018

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Treatment with soluble interleukin-15Ralpha exacerbates intracellular parasitic infection by blocking the development of memory CD8+ T cell response

21 June 2018

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CD8(+)-T-cell immunity against Toxoplasma gondii can be induced but not maintained in mice lacking conventional CD4(+) T cells

21 June 2018

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IL-7 is critical for homeostatic proliferation and survival of naive T cells

21 June 2018

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Immune CD8(+) T cells prevent reactivation of Toxoplasma gondii infection in the immunocompromised host.

21 June 2018

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Differential requirements for survival and proliferation of CD8 naïve or memory T cells

21 June 2018

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 June 2018

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CD4-mediated and CD8-mediated cytotoxic and proliferative immune responses to Toxoplasma gondii in seropositive humans

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877110

The murine Ki-67 cell proliferation antigen accumulates in the nucleolar and heterochromatic regions of interphase cells and at the periphery of the mitotic chromosomes in a process essential for cell cycle progression

21 June 2018

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IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877110

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 June 2018

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Mitogen- and antigen-specific proliferation of T cells in murine toxoplasmosis is inhibited by reactive nitrogen intermediates

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877110

Turnover of naive- and memory-phenotype T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877110

Impairment of the cellular immune response in acute murine toxoplasmosis: regulation of interleukin 2 production and macrophage-mediated inhibitory effects.

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877110

Interferon-gamma: the major mediator of resistance against Toxoplasma gondii

21 June 2018

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Direct and sensitive detection of a pathogenic protozoan, Toxoplasma gondii, by polymerase chain reaction.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877110

CD8+ T cells from mice vaccinated against Toxoplasma gondii are cytotoxic for parasite-infected or antigen-pulsed host cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877110

Simultaneous depletion of CD4+ and CD8+ T lymphocytes is required to reactivate chronic infection with Toxoplasma gondii

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877110

Cutting edge: requirement for IL-15 in the generation of primary and memory antigen-specific CD8 T cells

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

Asymmetric T lymphocyte division in the initiation of adaptive immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

A role for CD44 in the production of IFN-gamma and immunopathology during infection with Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

Control of homeostasis of CD8+ memory T cells by opposing cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

IL-15 Promotes the Survival of Naive and Memory Phenotype CD8+ T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

IL-12 signaling drives CD8+ T cell IFN-gamma production and differentiation of KLRG1+ effector subpopulations during Toxoplasma gondii Infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

Cutting edge: increased expression of Bcl-2 in antigen-specific memory CD8+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

Persistence of memory CD8 T cells in MHC class I-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

De novo pyrimidine biosynthesis is required for virulence of Toxoplasma gondii

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

Enforced expression of Bcl-2 partially restores cell numbers but not functions of TCRgammadelta intestinal intraepithelial T lymphocytes in IL-15-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

CD4+ T-cell help controls CD8+ T-cell memory via TRAIL-mediated activation-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

Generation of CD8 T cell memory is regulated by IL-12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

IL-4-secreting CD4+ T cells are crucial to the development of CD8+ T-cell responses against malaria liver stages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

Overexpression of IL-21 promotes massive CD8+ memory T cell accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

Perforin-mediated cytolysis plays a limited role in host resistance to Toxoplasma gondii.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877110

In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877110

c-Myc acts downstream of IL-15 in the regulation of memory CD8 T-cell homeostasis

30 October 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010842

Inhibition of in vitro spontaneous apoptosis by IL-7 correlates with bcl-2 up-regulation, cortical/mature immunophenotype, and better early cytoreduction of childhood T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

12 December 2020

T lymphocytes need IL-7 but not IL-4 or IL-6 to survive in vivo

1 reference

12 December 2020

Absence of a role for natural killer cells in the control of acute infection by Toxoplasma gondii oocysts

1 reference

12 December 2020

Antigen-specific CD8+ T cell clone protects against acute Toxoplasma gondii infection in mice

1 reference

12 December 2020

IL-10 mediates immunosuppression following primary infection with Toxoplasma gondii in mice

1 reference

12 December 2020

IL-7 stimulates protective immunity in mice against the intracellular pathogen, Toxoplasma gondii

1 reference

12 December 2020

IL-7 differentially modulates the expression of IFN-gamma and IL-4 in activated human T lymphocytes by transcriptional and post-transcriptional mechanisms

1 reference

12 December 2020

IL-15 prolongs the duration of CD8+ T cell-mediated immunity in mice infected with a vaccine strain of Toxoplasma gondii

1 reference

12 December 2020

NK cells enhance dendritic cell response against parasite antigens via NKG2D pathway

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0010842

Identifiers

DOI

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28 July 2017

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28 July 2017

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