Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate (Q33596829)

28 July 2017

Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate (English)

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28 July 2017

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1 reference

Xinkun Wang

1

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author name string

Xiaodong Bao

2

1 reference

28 July 2017

Ranu Pal

3

1 reference

28 July 2017

Abdulbaki Agbas

4

1 reference

28 July 2017

Elias K Michaelis

5

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28 July 2017

language of work or name

English

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publication date

7 June 2010

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28 July 2017

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28 July 2017

11

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28 July 2017

360

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https://scigraph.springernature.com/pub.10.1186/1471-2164-11-360

28 July 2017

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Microglial activation in Alzheimer's disease.

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NMDA receptor GluN2B (GluR epsilon 2/NR2B) subunit is crucial for channel function, postsynaptic macromolecular organization, and actin cytoskeleton at hippocampal CA3 synapses

21 June 2018

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Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation.

21 June 2018

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Neuroinflammation in Parkinson's disease: a target for neuroprotection?

21 June 2018

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21 June 2018

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Induction of toll-like receptor 9 signaling as a method for ameliorating Alzheimer's disease-related pathology

21 June 2018

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Heat shock protein 90: translation from cancer to Alzheimer's disease treatment?

21 June 2018

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Communication between the synapse and the nucleus in neuronal development, plasticity, and disease

21 June 2018

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Truncation of the Down syndrome candidate gene DYRK1A in two unrelated patients with microcephaly

21 June 2018

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A role for the spine apparatus in LTP and spatial learning

21 June 2018

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Dendritic and mitochondrial changes during glutamate excitotoxicity

21 June 2018

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Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex

21 June 2018

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Calcium-dependent NMDA-induced dendritic injury and MAP2 loss in acute hippocampal slices

21 June 2018

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Genetic program of neuronal differentiation and growth induced by specific activation of NMDA receptors

21 June 2018

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From the Cover: Indispensability of the glutamate transporters GLAST and GLT1 to brain development

21 June 2018

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The Cbl interactome and its functions

21 June 2018

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Divergent regulation of Pyk2/CAKbeta phosphorylation by Ca2+ and cAMP in the hippocampus

21 June 2018

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The actin cytoskeleton: integrating form and function at the synapse

21 June 2018

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Regulation of the proapoptotic activity of huntingtin interacting protein 1 by Dyrk1 and caspase-3 in hippocampal neuroprogenitor cells

21 June 2018

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Don't get too excited: mechanisms of glutamate-mediated Purkinje cell death

21 June 2018

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Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance

21 June 2018

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Depolarization activates ERK and proline-rich tyrosine kinase 2 (PYK2) independently in different cellular compartments in hippocampal slices

21 June 2018

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An RNA-interacting protein, SYNCRIP (heterogeneous nuclear ribonuclear protein Q1/NSAP1) is a component of mRNA granule transported with inositol 1,4,5-trisphosphate receptor type 1 mRNA in neuronal dendrites

21 June 2018

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Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network

21 June 2018

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Gene regulation and DNA damage in the ageing human brain

21 June 2018

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Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites

21 June 2018

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Molecular mechanisms of glutamate-dependent neurodegeneration in ischemia and traumatic brain injury

21 June 2018

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Mitochondrial dysfunction and glutamate excitotoxicity studied in primary neuronal cultures

21 June 2018

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A key role for TRPM7 channels in anoxic neuronal death

21 June 2018

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Glutamatergic systems in Alzheimer's disease.

21 June 2018

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Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis

21 June 2018

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Glutamate receptor function in learning and memory

21 June 2018

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Aha1 binds to the middle domain of Hsp90, contributes to client protein activation, and stimulates the ATPase activity of the molecular chaperone

21 June 2018

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MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data

21 June 2018

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A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

21 June 2018

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Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis

21 June 2018

1 reference

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The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis

21 June 2018

1 reference

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A Bayesian framework for the analysis of microarray expression data: regularized t -test and statistical inferences of gene changes

21 June 2018

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Significance analysis of microarrays applied to the ionizing radiation response

21 June 2018

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Molecular mechanisms of calcium-dependent excitotoxicity

21 June 2018

1 reference

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Immunocytochemical and in situ hybridization studies of the expression and distribution of three subunits of a complex with N-methyl-D-aspartate receptor-like properties

21 June 2018

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Calcium from internal stores modifies dendritic spine shape

21 June 2018

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Functional consequences of mutations in the early growth response 2 gene (EGR2) correlate with severity of human myelinopathies.

21 June 2018

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Differential induction of c-Fos, c-Jun and Jun B in the rat central nervous system following unilateral entorhinal cortex lesion

21 June 2018

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The number of glutamate transporter subtype molecules at glutamatergic synapses: chemical and stereological quantification in young adult rat brain

21 June 2018

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Activation of excitatory amino acid receptors in the rat hippocampal slice increases intracellular Cl- and cell volume

21 June 2018

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NRP/B, a novel nuclear matrix protein, associates with p110(RB) and is involved in neuronal differentiation

21 June 2018

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Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging

21 June 2018

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Life and death of neurons in the aging brain

21 June 2018

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Ionized intracellular calcium concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators

21 June 2018

1 reference

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Glutamate toxicity on a PC12 cell line involves glutathione (GSH) depletion and oxidative stress

21 June 2018

1 reference

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Association of c-fos mRNA expression and excitotoxicity in primary cultures of mouse neocortical and cerebellar neurons

21 June 2018

1 reference

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Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1

21 June 2018

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Differential regulation of proline-rich tyrosine kinase 2/cell adhesion kinase beta (PYK2/CAKbeta) and pp125(FAK) by glutamate and depolarization in rat hippocampus.

21 June 2018

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Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

21 June 2018

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SNAP family of NSF attachment proteins includes a brain-specific isoform

21 June 2018

1 reference

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Injury-induced long-term expression of immediate early genes in the rat superior cervical ganglion

21 June 2018

1 reference

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Glutamate: its role in learning, memory, and the aging brain

21 June 2018

1 reference

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Effect of acute stress on hippocampal glutamate levels and spectrin proteolysis in young and aged rats

21 June 2018

1 reference

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Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

21 June 2018

1 reference

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Stimulation of ionotropic glutamate receptors activates transcription factor NF-kappa B in primary neurons

21 June 2018

1 reference

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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

21 June 2018

1 reference

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17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro

21 June 2018

1 reference

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The neurotoxicity of excitatory amino acids is produced by passive chloride influx.

21 June 2018

1 reference

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Selective alteration of mouse brain neurotransmitter release with age.

21 June 2018

1 reference

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Excitatory aminoacid antagonists provide a therapeutic approach to neurological disorders.

21 June 2018

1 reference

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Excitatory amino acid neurotransmission: NMDA receptors and Hebb-type synaptic plasticity

21 June 2018

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21 June 2018

1 reference

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21 June 2018

Excitotoxic cell death

1 reference

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Urea biosynthesis I. The urea cycle and relationships to the citric acid cycle

21 June 2018

1 reference

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Differential gene expression in the rat hippocampus during learning of an operant conditioning task.

21 June 2018

1 reference

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Age and neuroinflammation: a lifetime of psychoneuroimmune consequences.

30 October 2018

1 reference

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SYNCRIP, a component of dendritically localized mRNPs, binds to the translation regulator BC200 RNA.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896956

CREB and NF-kappaB transcription factors regulate sensitivity to excitotoxic and oxidative stress induced neuronal cell death.

30 October 2018

1 reference

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Glutamate induces rapid loss of axonal neurofilament proteins from cortical neurons in vitro

30 October 2018

1 reference

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Human tumorous imaginal disc 1 (TID1) associates with Trk receptor tyrosine kinases and regulates neurite outgrowth in nnr5-TrkA cells.

30 October 2018

1 reference

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Fibroblast glutamate transport in aging and in AD: correlations with disease severity

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896956

30 October 2018

1 reference

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N-methyl-D-aspartate receptor and L-type voltage-gated Ca2+ channel activation mediate proline-rich tyrosine kinase 2 phosphorylation during cerebral ischemia in rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896956

Selective dendrite-targeting of mRNAs of NR1 splice variants without exon 5: identification of a cis-acting sequence and isolation of sequence-binding proteins

30 October 2018

1 reference

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A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia

30 October 2018

1 reference

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Microtubule-associated protein 2 (MAP2) associates with the NMDA receptor and is spatially redistributed within rat hippocampal neurons after oxygen-glucose deprivation.

30 October 2018

1 reference

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The translocation of focal adhesion kinase in brain synaptosomes is regulated by phosphorylation and actin assembly

30 October 2018

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Oxidative glutamate toxicity can be a component of the excitotoxicity cascade.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896956

Aging is associated with a decrease in synaptosomal glutamate uptake and an increase in the susceptibility of synaptosomal vitamin E to oxidative stress.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896956

Nuclear factor-kappa B contributes to excitotoxin-induced apoptosis in rat striatum.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896956

Quantitative synaptic alterations in the human neocortex during normal aging

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896956

Modulation of neuronal migration by NMDA receptors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896956

Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2896956

Taxol stabilizes [Ca2+]i and protects hippocampal neurons against excitotoxicity

30 October 2018

1 reference

12 December 2020

Neocortical cell counts in normal human adult aging

1 reference

12 December 2020

Bench to bedside: the glutamate connection

1 reference

12 December 2020

Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases

1 reference

12 December 2020

Diphosphorylation and involvement of extracellular signal-regulated kinases (ERK1/2) in glutamate-induced apoptotic-like death in cultured rat cortical neurons

1 reference

12 December 2020

Preliminary evaluation of an in vitro test for assessment of excitotoxicity by measurement of early gene (c-fos mRNA) levels

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2164-11-360

1 reference

Dimensions Publication ID

28 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2164-11-360

9 September 2019

1 reference

28 July 2017

1 reference