Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells (Q33604925)

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English	Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells	scientific article

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scholarly article

1 reference

Europe PubMed Central

28 July 2017

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells (English)

1 reference

Europe PubMed Central

28 July 2017

Laurence Zitvogel

17

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22

object named as

Cédric Rébé

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François Ghiringhelli

23

object named as

François Ghiringhelli

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21

object named as

Lionel Apetoh

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Sylvain Ladoire

2

object named as

Sylvain Ladoire

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4

object named as

Julie Vincent

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Bruno Chauffert

15

object named as

Bruno Chauffert

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Mélanie Bruchard

5

object named as

Mélanie Bruchard

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Bernhard Ryffel

19

object named as

Bernhard Ryffel

0 references

François Martin

14

object named as

François Martin

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16

object named as

Eric Solary

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Grégoire Mignot

3

object named as

Grégoire Mignot

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Gabriele Multhoff

object named as

Gabriele Multhoff

12

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author name string

Fanny Chalmin

1

1 reference

Europe PubMed Central

28 July 2017

Jean-Paul Remy-Martin

6

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Europe PubMed Central

28 July 2017

Wilfrid Boireau

7

1 reference

Europe PubMed Central

28 July 2017

Alain Rouleau

8

1 reference

Europe PubMed Central

28 July 2017

Benoit Simon

9

1 reference

Europe PubMed Central

28 July 2017

David Lanneau

10

1 reference

Europe PubMed Central

28 July 2017

Aurélie De Thonel

11

1 reference

Europe PubMed Central

28 July 2017

Arlette Hamman

13

1 reference

Europe PubMed Central

28 July 2017

Carmen Garrido

18

1 reference

Europe PubMed Central

28 July 2017

Christophe Borg

20

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Europe PubMed Central

28 July 2017

language of work or name

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publication date

19 January 2010

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Europe PubMed Central

28 July 2017

Journal of Clinical Investigation

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Europe PubMed Central

28 July 2017

120

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Europe PubMed Central

28 July 2017

457-471

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Europe PubMed Central

28 July 2017

2

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Europe PubMed Central

28 July 2017

Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells

1 reference

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28 July 2018

Myeloid-derived suppressor cells: linking inflammation and cancer

1 reference

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The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies

1 reference

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28 July 2018

Myeloid-derived suppressor cells as regulators of the immune system

1 reference

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Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

1 reference

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Activated STAT3 is a mediator and biomarker of VEGF endothelial activation

1 reference

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Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice.

1 reference

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STAT3 can be activated through paracrine signaling in breast epithelial cells

1 reference

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28 July 2018

Subsets of myeloid-derived suppressor cells in tumor-bearing mice

1 reference

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CD4+CD25+ Tregs control the TRAIL-dependent cytotoxicity of tumor-infiltrating DCs in rodent models of colon cancer

1 reference

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Revisited BIA-MS combination: entire "on-a-chip" processing leading to the proteins identification at low femtomole to sub-femtomole levels

1 reference

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Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

1 reference

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28 July 2018

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy

1 reference

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Lung cancer patients' CD4(+) T cells are activated in vitro by MHC II cell-based vaccines despite the presence of myeloid-derived suppressor cells

1 reference

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Mechanism of all-trans retinoic acid effect on tumor-associated myeloid-derived suppressor cells

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Tumour-released exosomes and their implications in cancer immunity.

1 reference

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Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function

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Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

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Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer

1 reference

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28 July 2018

The terminology issue for myeloid-derived suppressor cells

1 reference

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Extracellular heat shock protein-70 induces endotoxin tolerance in THP-1 cells.

1 reference

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28 July 2018

Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810085

28 July 2018

All-trans-retinoic acid improves differentiation of myeloid cells and immune response in cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810085

28 July 2018

Exosomes: a common pathway for a specialized function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810085

28 July 2018

Prospects for exosomes in immunotherapy of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810085

28 July 2018

Heat shock proteins in cancer: chaperones of tumorigenesis

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Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity

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Tumor exosomes expressing Fas ligand mediate CD8+ T-cell apoptosis

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28 July 2018

Endogenous ligands of Toll-like receptors

1 reference

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CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative

1 reference

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Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

1 reference

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Hyperactivation of STAT3 is involved in abnormal differentiation of dendritic cells in cancer.

1 reference

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Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein

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Exosome release is regulated by a calcium-dependent mechanism in K562 cells

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Activation of natural killer cells by heat shock protein 70.

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28 July 2018

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The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway

1 reference

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HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway

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Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810085

28 July 2018

Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810085

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Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming

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Escaping cell death: survival proteins in cancer

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Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6

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Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein

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IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients.

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30 October 2018

Heat shock proteins and immune system

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30 October 2018

Induction of myeloid-derived suppressor cells by tumor exosomes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810085

30 October 2018

Activation of hepatocytes by extracellular heat shock protein 72.

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30 October 2018

HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway

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Arginase, prostaglandins, and myeloid-derived suppressor cells in renal cell carcinoma

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30 October 2018

Human tumor-released microvesicles promote the differentiation of myeloid cells with transforming growth factor-beta-mediated suppressive activity on T lymphocytes

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30 October 2018

Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: a mechanism of tumor evasion

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30 October 2018

Malignant effusions and immunogenic tumour-derived exosomes

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Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20093776

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A 71-kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis

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https://pubmed.ncbi.nlm.nih.gov/20093776

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based on heuristic

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Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells

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https://pubmed.ncbi.nlm.nih.gov/20093776

12 December 2020

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Identification of a New Subset of Myeloid Suppressor Cells in Peripheral Blood of Melanoma Patients With Modulation by a Granulocyte-Macrophage Colony-Stimulation Factor–Based Antitumor Vaccine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20093776

12 December 2020

based on heuristic

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HSP70 stimulates cytokine production through a CD14-dependant pathway, demonstrating its dual role as a chaperone and cytokine

1 reference

https://pubmed.ncbi.nlm.nih.gov/20093776

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based on heuristic

inferred from PubMed ID database lookup

The heat shock protein gp96 induces maturation of dendritic cells and down-regulation of its receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20093776

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based on heuristic

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Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20093776

12 December 2020

based on heuristic

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Identifiers

10.1172/JCI40483

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

1 reference

Europe PubMed Central

28 July 2017

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