Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation (Q33611148)

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8 January 2020

title

Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation (English)

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8 January 2020

7

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8 January 2020

author name string

Xiuli Bi

1

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8 January 2020

Chang Tong

2

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8 January 2020

Ashley Dockendorff

3

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8 January 2020

Laura Bancroft

4

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8 January 2020

Lindsay Gallagher

5

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8 January 2020

Grace Guzman

6

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8 January 2020

Leonard H Augenlicht

8

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8 January 2020

Wancai Yang

9

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8 January 2020

language of work or name

English

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publication date

12 June 2008

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8 January 2020

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8 January 2020

volume

29

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8 January 2020

issue

7

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8 January 2020

page(s)

1435-1440

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c-Jun NH2-terminal kinase 1 plays a critical role in intestinal homeostasis and tumor suppression

8 January 2020

cites work

1 reference

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Regulation of mucin expression: mechanistic aspects and implications for cancer and inflammatory diseases

21 June 2018

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21 June 2018

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p27kip1 in intestinal tumorigenesis and chemoprevention in the mouse

21 June 2018

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Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice

21 June 2018

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21 June 2018

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21 June 2018

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Aberrant expression and localization of decorin in human oral dysplasia and squamous cell carcinoma

21 June 2018

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Cadherins as Modulators of Cellular Phenotype

21 June 2018

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The role of decorin in collagen fibrillogenesis and skin homeostasis

21 June 2018

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The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

21 June 2018

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Colorectal cancer in mice genetically deficient in the mucin Muc2

21 June 2018

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A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice

21 June 2018

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Decorin-mediated signal transduction in endothelial cells. Involvement of Akt/protein kinase B in up-regulation of p21(WAF1/CIP1) but not p27(KIP1).

21 June 2018

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CDK inhibitors: positive and negative regulators of G1-phase progression

21 June 2018

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Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis

21 June 2018

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The prognostic significance of altered cyclin-dependent kinase inhibitors in human cancer

21 June 2018

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Prognostic implications of expression of the cell cycle inhibitor protein p27Kip1.

21 June 2018

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p27kip1: a multifunctional cyclin-dependent kinase inhibitor with prognostic significance in human cancers

21 June 2018

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Decorin is a biological ligand for the epidermal growth factor receptor

21 June 2018

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Matrix proteoglycans: from molecular design to cellular function

21 June 2018

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Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases

21 June 2018

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Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor

21 June 2018

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Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases

21 June 2018

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Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility

21 June 2018

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Early alteration of cell-cycle-regulated gene expression in colorectal neoplasia

21 June 2018

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 June 2018

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A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors

21 June 2018

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Topological control of p21WAF1/CIP1 expression in normal and neoplastic tissues

21 June 2018

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De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells

21 June 2018

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Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin

21 June 2018

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Crossref

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN141

Organization and regulatory aspects of the human intestinal mucin gene (MUC2) locus.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGN141

Targeted inactivation of p27kip1 is sufficient for large and small intestinal tumorigenesis in the mouse, which can be augmented by a Western-style high-risk diet.

21 January 2018

1 reference

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Decorin inhibits macrophage colony-stimulating factor proliferation of macrophages and enhances cell survival through induction of p27(Kip1) and p21(Waf1).

30 October 2018

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Down-regulation of p27 is a significant predictor of poor overall survival and may facilitate metastasis in colorectal carcinomas

30 October 2018

1 reference

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In vitro growth inhibition of ovarian cancer cells by decorin: synergism of action between decorin and carboplatin

30 October 2018

1 reference

12 December 2020

Sustained down-regulation of the epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo

1 reference

12 December 2020

Targeted inactivation of the p21(WAF1/cip1) gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosal

1 reference

12 December 2020

Role of p27(Kip1) in human intestinal cell differentiation

1 reference

12 December 2020

Loss of p27 expression predicts poor prognosis in patients with Dukes' B stage or proximal colorectal cancer

1 reference

12 December 2020

Decorin-induced Growth Suppression Is Associated with Up-regulation of p21, an Inhibitor of Cyclin-dependent Kinases

1 reference

12 December 2020

Gastrointestinal expression and partial cDNA cloning of murine Muc2

1 reference

12 December 2020

Identifiers

DOI

10.1093/CARCIN/BGN141

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550571%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18550571%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference