Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim. (Q33618246)

28 July 2017

Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim. (English)

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28 July 2017

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J Konishi

1

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28 July 2017

F Yi

2

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28 July 2017

X Chen

3

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28 July 2017

H Vo

4

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28 July 2017

D P Carbone

5

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28 July 2017

T P Dang

6

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28 July 2017

language of work or name

English

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publication date

2 November 2009

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28 July 2017

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28 July 2017

29

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4

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28 July 2017

589-596

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https://scigraph.springernature.com/pub.10.1038/onc.2009.366

28 July 2017

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cites work

BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Induction of BIM is essential for apoptosis triggered by EGFR kinase inhibitors in mutant EGFR-dependent lung adenocarcinomas

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Notch3 activation modulates cell growth behaviour and cross-talk to Wnt/TCF signalling pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

The multifaceted role of Notch in cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

FOXO-dependent expression of the proapoptotic protein Bim: pivotal role for apoptosis signaling in endothelial progenitor cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Notch oncoproteins depend on gamma-secretase/presenilin activity for processing and function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Notch-1 induction, a novel activity of SV40 required for growth of SV40-transformed human mesothelial cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Involvement of Notch1 in the development of mouse mammary tumors

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Determinants of Notch-3 receptor expression and signaling in vascular smooth muscle cells: implications in cell-cycle regulation.

14 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Gamma-secretase inhibitor prevents Notch3 activation and reduces proliferation in human lung cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Development and cancer: lessons learned in the pancreas.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2813325

Pro-apoptotic Bim Induction in Response to Nerve Growth Factor Deprivation Requires Simultaneous Activation of Three Different Death Signaling Pathways

30 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Suppression of p53 by Notch in lymphomagenesis: implications for initiation and regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Chromosome 19 translocation, overexpression of Notch3, and human lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Ras pathway signals are required for notch-mediated oncogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Melphalan-induced apoptosis in multiple myeloma cells is associated with a cleavage of Mcl-1 and Bim and a decrease in the Mcl-1/Bim complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.366

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.366

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Dimensions Publication ID

28 July 2017

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28 July 2017

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