Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability (Q33618895)

28 July 2017

title

Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability (English)

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28 July 2017

Don W Cleveland

5

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author name string

Andrew J Holland

1

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28 July 2017

Weijie Lan

2

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28 July 2017

Sherry Niessen

3

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28 July 2017

Heather Hoover

4

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28 July 2017

language of work or name

English

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publication date

1 January 2010

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28 July 2017

published in

Journal of Cell Biology

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28 July 2017

volume

188

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28 July 2017

issue

2

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28 July 2017

page(s)

191-198

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Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells

28 July 2017

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A mechanism linking extra centrosomes to chromosomal instability

21 June 2018

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Ab ovo or de novo? Mechanisms of centriole duplication

21 June 2018

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The SCF Slimb ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication.

21 June 2018

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The SCF/Slimb ubiquitin ligase limits centrosome amplification through degradation of SAK/PLK4.

21 June 2018

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21 June 2018

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Centrosome amplification can initiate tumorigenesis in flies.

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Overexpressing centriole-replication proteins in vivo induces centriole overduplication and de novo formation.

21 June 2018

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Centriole overduplication through the concurrent formation of multiple daughter centrioles at single maternal templates

21 June 2018

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Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells.

21 June 2018

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21 June 2018

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21 June 2018

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SAK/PLK4 is required for centriole duplication and flagella development

21 June 2018

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The Polo kinase Plk4 functions in centriole duplication

21 June 2018

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Sak/Plk4 and mitotic fidelity

21 June 2018

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Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability.

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Comparative expression of the mitotic regulators SAK and PLK in colorectal cancer

21 June 2018

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Sak serine-threonine kinase acts as an effector of Tec tyrosine kinase

21 June 2018

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A chemical switch for inhibitor-sensitive alleles of any protein kinase

21 June 2018

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Genetic instability in colorectal cancers

21 June 2018

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Constitutive expression of murine Sak-a suppresses cell growth and induces multinucleation

21 June 2018

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Centrosome dysfunction in Drosophila neural stem cells causes tumors that are not due to genome instability.

21 June 2018

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RNA-dependent integrin alpha3 protein localization regulated by the Muscleblind-like protein MLP1

21 January 2018

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Plk4 haploinsufficiency causes mitotic infidelity and carcinogenesis.

21 January 2018

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Cullin 1 functions as a centrosomal suppressor of centriole multiplication by regulating polo-like kinase 4 protein levels

21 January 2018

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https://api.crossref.org/works/10.1083%2FJCB.200911102

21 January 2018

Identifiers

DOI

10.1083/JCB.200911102

1 reference

28 July 2017

1 reference

28 July 2017

1 reference