Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling (Q33620621)

28 July 2017

Monoacylglycerol lipase inhibition blocks chronic stress-induced depressive-like behaviors via activation of mTOR signaling (English)

1 reference

28 July 2017

8

Benjamin F Cravatt

1 reference

28 July 2017

Peng Zhong

1

1 reference

28 July 2017

Wei Wang

2

1 reference

28 July 2017

Bin Pan

3

1 reference

28 July 2017

Xiaojie Liu

4

1 reference

28 July 2017

Zhen Zhang

5

1 reference

28 July 2017

Jonathan Z Long

6

1 reference

28 July 2017

Han-ting Zhang

7

1 reference

28 July 2017

Qing-song Liu

9

1 reference

28 July 2017

language of work or name

English

0 references

publication date

30 January 2014

1 reference

28 July 2017

Neuropsychopharmacology

1 reference

28 July 2017

39

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28 July 2017

1763-1776

1 reference

28 July 2017

7

1 reference

https://scigraph.springernature.com/pub.10.1038/npp.2014.24

28 July 2017

0 references

cites work

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mTOR activation is required for the antidepressant effects of mGluR₂/₃ blockade

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Acute restraint stress enhances hippocampal endocannabinoid function via glucocorticoid receptor activation

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Reversible gating of endocannabinoid plasticity in the amygdala by chronic stress: a potential role for monoacylglycerol lipase inhibition in the prevention of stress-induced behavioral adaptation

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The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder

21 June 2018

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Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats

21 June 2018

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Inhibition of endocannabinoid catabolic enzymes elicits anxiolytic-like effects in the marble burying assay

21 June 2018

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mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

21 June 2018

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21 June 2018

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The endocannabinoid 2-arachidonoylglycerol produced by diacylglycerol lipase alpha mediates retrograde suppression of synaptic transmission

21 June 2018

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Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice

21 June 2018

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A role for 2-arachidonoylglycerol and endocannabinoid signaling in the locomotor response to novelty induced by olfactory bulbectomy

21 June 2018

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mTOR signaling: at the crossroads of plasticity, memory and disease

21 June 2018

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Dual blockade of FAAH and MAGL identifies behavioral processes regulated by endocannabinoid crosstalk in vivo.

21 June 2018

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The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants

21 June 2018

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Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling

21 June 2018

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Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling

21 June 2018

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Characterization of monoacylglycerol lipase inhibition reveals differences in central and peripheral endocannabinoid metabolism

21 June 2018

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The psychiatric side-effects of rimonabant

21 June 2018

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Differential effects of chronic unpredictable stress on hippocampal CB1 receptors in male and female rats

21 June 2018

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Endocannabinoids in the treatment of mood disorders: evidence from animal models

21 June 2018

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Endocannabinoid signals in the control of emotion

21 June 2018

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Antiaversive effects of cannabinoids: is the periaqueductal gray involved?

21 June 2018

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Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

21 June 2018

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Serum endocannabinoid content is altered in females with depressive disorders: a preliminary report

21 June 2018

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IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress

21 June 2018

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A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol

21 June 2018

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Enhancement of endocannabinoid signaling and the pharmacotherapy of depression.

21 June 2018

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The endogenous cannabinoid anandamide has effects on motivation and anxiety that are revealed by fatty acid amide hydrolase (FAAH) inhibition

21 June 2018

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Signalling to translation: how signal transduction pathways control the protein synthetic machinery

21 June 2018

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Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment

21 June 2018

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Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis

21 June 2018

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Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects

21 June 2018

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Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023150

Decreased depression in marijuana users.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023150

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023150

Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023150

Modulation of anxiety through blockade of anandamide hydrolysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023150

Behavioural and biochemical evidence for interactions between Delta 9-tetrahydrocannabinol and nicotine.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4023150

Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

21 June 2018

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Research and treatment approaches to depression

21 June 2018

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Fatty acid amide hydrolase is located preferentially in large neurons in the rat central nervous system as revealed by immunohistochemistry

21 June 2018

1 reference

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A second endogenous cannabinoid that modulates long-term potentiation

21 June 2018

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Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

21 June 2018

1 reference

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Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

21 June 2018

1 reference

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Reduction of sucrose preference by chronic unpredictable mild stress, and its restoration by a tricyclic antidepressant

21 June 2018

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Depression: a new animal model sensitive to antidepressant treatments

21 June 2018

1 reference

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Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex.

21 June 2018

1 reference

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Involvement of the opioid system in the anxiolytic-like effects induced by Delta(9)-tetrahydrocannabinol

21 January 2018

1 reference

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Depression-like phenotype following chronic CB1 receptor antagonism

21 January 2018

1 reference

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Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress.

21 January 2018

1 reference

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Targeting the endocannabinoid system in the treatment of fragile X syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2014.24

Differential role of anandamide and 2-arachidonoylglycerol in memory and anxiety-like responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2014.24

A silver bullet for the treatment of depression?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2014.24

Segregation of two endocannabinoid-hydrolyzing enzymes into pre- and postsynaptic compartments in the rat hippocampus, cerebellum and amygdala.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2014.24

Downregulation of endocannabinoid signaling in the hippocampus following chronic unpredictable stress

21 January 2018

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https://api.crossref.org/works/10.1038%2FNPP.2014.24

CB1 receptor signaling regulates social anxiety and memory.

21 January 2018

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Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid signaling.

21 January 2018

1 reference

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Differential regulation of the endocannabinoids anandamide and 2-arachidonylglycerol within the limbic forebrain by dopamine receptor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2014.24

Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2014.24

Inhibition of fatty-acid amide hydrolase accelerates acquisition and extinction rates in a spatial memory task

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNPP.2014.24

Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus.

21 January 2018

1 reference

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Chronic restraint stress impairs endocannabinoid mediated suppression of GABAergic signaling in the hippocampus of adult male rats

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24476943

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Rimonabant for the treatment of obesity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24476943

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NPP.2014.24

1 reference

Dimensions Publication ID

28 July 2017

1025898473

0 references

Fatcat ID

release_5bi5dbn3enepja7kzsd54ixrli

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5bi5dbn3enepja7kzsd54ixrli

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

4023150

1 reference

28 July 2017

1 reference