Novel CD8+ Treg suppress EAE by TGF-beta- and IFN-gamma-dependent mechanisms (Q33622404)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19768696%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

Novel CD8+ Treg suppress EAE by TGF-beta- and IFN-gamma-dependent mechanisms (English)

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8 February 2020

2

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8 February 2020

author name string

Mei-Ling Chen

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19768696%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Deneen Kozoriz

series ordinal

3

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8 February 2020

Howard L Weiner

series ordinal

4

1 reference

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8 February 2020

language of work or name

English

0 references

publication date

1 December 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19768696%20AND%20SRC:MED&resulttype=core&format=json

European Journal of Immunology

8 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19768696%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

39

1 reference

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8 February 2020

page(s)

3423-3435

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19768696%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

12

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19768696%20AND%20SRC:MED&resulttype=core&format=json

IL-17 signaling-independent central nervous system autoimmunity is negatively regulated by TGF-beta

8 February 2020

cites work

1 reference

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Revival of CD8+ Treg-mediated suppression

28 July 2018

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Latency-associated peptide identifies a novel CD4+CD25+ regulatory T cell subset with TGFbeta-mediated function and enhanced suppression of experimental autoimmune encephalomyelitis

28 July 2018

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Natural regulatory T cells: mechanisms of suppression

28 July 2018

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Role of IFN-gamma in induction of Foxp3 and conversion of CD4+ CD25- T cells to CD4+ Tregs

28 July 2018

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The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory T-cell biology

28 July 2018

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Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy?

28 July 2018

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License to heal: bidirectional interaction of antigen-specific regulatory T cells and tolerogenic APC.

28 July 2018

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Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivo

28 July 2018

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TGF-beta activation by traction?

28 July 2018

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Autoimmune concepts of multiple sclerosis as a basis for selective immunotherapy: from pipe dreams to (therapeutic) pipelines

28 July 2018

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Interferon gamma enhances both in vitro and in vivo priming of CD4+ T cells for IL-4 production.

28 July 2018

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Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7

28 July 2018

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Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

28 July 2018

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

28 July 2018

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Regulatory functions of CD8+CD28– T cells in an autoimmune disease model

28 July 2018

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CD4+CD25+ T regulatory cells control anti-islet CD8+ T cells through TGF-beta-TGF-beta receptor interactions in type 1 diabetes

28 July 2018

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Regulatory CD8+ T cells fine-tune the myelin basic protein-reactive T cell receptor V beta repertoire during experimental autoimmune encephalomyelitis

28 July 2018

1 reference

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Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.

28 July 2018

1 reference

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

28 July 2018

1 reference

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Interferon gamma is required for activation-induced death of T lymphocytes

28 July 2018

1 reference

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Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells

28 July 2018

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CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

28 July 2018

1 reference

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Th1 cytokines, programmed cell death, and alloreactive T cell clone size in transplant tolerance.

28 July 2018

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Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells

28 July 2018

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Glatiramer acetate (Copaxone) therapy induces CD8(+) T cell responses in patients with multiple sclerosis

28 July 2018

1 reference

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A pathogenic role for myelin-specific CD8(+) T cells in a model for multiple sclerosis

28 July 2018

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Interferon gamma eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells

28 July 2018

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Transforming growth factor-beta: latent forms, binding proteins and receptors

28 July 2018

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Murine CD8+ T cells that specifically delete autologous CD4+ T cells expressing V beta 8 TCR: a role of the Qa-1 molecule

28 July 2018

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Suppression of the immune response by cytotoxic T cells

28 July 2018

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Effect of anti-interferon-gamma and anti-interleukin-2 monoclonal antibody treatment on the development of actively and passively induced experimental allergic encephalomyelitis in the SJL/J mouse.

28 July 2018

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Role of CD8+ T cells in murine experimental allergic encephalomyelitis

28 July 2018

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28 July 2018

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CD8+ T cells control the TH phenotype of MBP-reactive CD4+ T cells in EAE mice

21 January 2018

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Analysis of regulatory CD8 T cells in Qa-1-deficient mice

21 January 2018

1 reference

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Oral CD3-specific antibody suppresses autoimmune encephalomyelitis by inducing CD4+ CD25- LAP+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939441

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939441

IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939441

Interferon-gamma confers resistance to experimental allergic encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939441

CD40Ig treatment results in allograft acceptance mediated by CD8CD45RC T cells, IFN-gamma, and indoleamine 2,3-dioxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939441

Inhibition of T cell responses by activated human CD8+ T cells is mediated by interferon-gamma and is defective in chronic progressive multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939441

The role of gamma interferon in antimicrobial immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939441

Modulation of tryptophan catabolism by regulatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939441

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939441

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939441

A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939441

T cells can present antigens such as HIV gp120 targeted to their own surface molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.200939441

A novel alloantigen-specific CD8+PD1+ regulatory T cell induced by ICOS-B7h blockade in vivo.

21 January 2018

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Cutting edge: CD8+CD122+ regulatory T cells produce IL-10 to suppress IFN-gamma production and proliferation of CD8+ T cells.

30 October 2018

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Peripheral CD8+CD25+ T lymphocytes from MHC class II-deficient mice exhibit regulatory activity

30 October 2018

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Peptide-specific CD8 T regulatory cells use IFN-gamma to elaborate TGF-beta-based suppression.

30 October 2018

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The CD8 T cell compartment plays a dominant role in the deficiency of Brown-Norway rats to mount a proper type 1 immune response.

30 October 2018

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Essential role of TGF-beta in the natural resistance to experimental allergic encephalomyelitis in rats.

30 October 2018

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IFN-gamma-deficient mice develop experimental autoimmune uveitis in the context of a deviant effector response

30 October 2018

1 reference

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Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814307

Suppression of experimental allergic encephalomyelitis by intraventricular administration of interferon-gamma in Lewis rats

30 October 2018

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12 December 2020

Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice

1 reference

12 December 2020

IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

1 reference

12 December 2020

Accelerated collagen-induced arthritis in IFN-gamma receptor-deficient mice

1 reference

12 December 2020

EAE in beta-2 microglobulin-deficient mice: axonal damage is not dependent on MHC-I restricted immune responses

1 reference

12 December 2020

Therapeutic induction of regulatory, cytotoxic CD8+ T cells in multiple sclerosis

1 reference

12 December 2020

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Essential role of CD8+CD122+ regulatory T cells in the recovery from experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Isolation and characterization of CD8+ regulatory T cells in multiple sclerosis

1 reference

12 December 2020

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

1 reference

12 December 2020

Myelin antigen-specific CD8+ T cells are encephalitogenic and produce severe disease in C57BL/6 mice

1 reference

12 December 2020

Intrathecal delivery of IFN-gamma protects C57BL/6 mice from chronic-progressive experimental autoimmune encephalomyelitis by increasing apoptosis of central nervous system-infiltrating lymphocytes

1 reference

12 December 2020

CD4+CD25- T cells that express latency-associated peptide on the surface suppress CD4+CD45RBhigh-induced colitis by a TGF-beta-dependent mechanism

1 reference

12 December 2020

Activated suppressor cell dysfunction in progressive multiple sclerosis

1 reference

12 December 2020

Enhancement of experimental allergic encephalomyelitis in mice by antibodies against IFN-gamma

1 reference

12 December 2020

Identifiers

DOI

10.1002/EJI.200939441

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19768696%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19768696%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference