BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability (Q33624839)

28 July 2017

title

BRCA1 deficiency exacerbates estrogen-induced DNA damage and genomic instability (English)

1 reference

28 July 2017

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Kyle B Matchett

2

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Lorenzo Manti

Lorenzo Manti

12

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Kevin Cooper

Kevin M Cooper

4

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Simon S. McDade

Simon S McDade

13

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Derek J. Richard

Derek J Richard

18

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Kevin M. Prise

Kevin M Prise

15

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author name string

Kienan I Savage

1

1 reference

28 July 2017

Eliana M Barros

3

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28 July 2017

Gareth W Irwin

5

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28 July 2017

Julia J Gorski

6

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28 July 2017

Katy S Orr

7

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28 July 2017

Jekaterina Vohhodina

8

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28 July 2017

Joy N Kavanagh

9

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28 July 2017

Angelina F Madden

10

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28 July 2017

Alexander Powell

11

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28 July 2017

Ben Ho Park

14

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28 July 2017

Stuart A McIntosh

16

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28 July 2017

Manuel Salto-Tellez

17

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28 July 2017

Christopher T Elliott

19

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28 July 2017

D Paul Harkin

20

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28 July 2017

language of work or name

English

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publication date

17 March 2014

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28 July 2017

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28 July 2017

volume

74

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28 July 2017

issue

10

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28 July 2017

page(s)

2773-2784

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Oophorectomy after menopause and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

28 July 2017

cites work

1 reference

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Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

14 July 2018

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Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells

14 July 2018

1 reference

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BRCA1 is required for postreplication repair after UV-induced DNA damage

14 July 2018

1 reference

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A dual role of BRCA1 in two distinct homologous recombination mediated repair in response to replication arrest

14 July 2018

1 reference

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BRCA1 tumour suppression occurs via heterochromatin-mediated silencing.

14 July 2018

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Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis.

14 July 2018

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Urine biomarkers of risk in the molecular etiology of breast cancer.

14 July 2018

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Luteinising hormone releasing hormone agonists (LH-RHa) in premenopausal early breast cancer patients: current role and future perspectives.

14 July 2018

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BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription

14 July 2018

1 reference

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Effects of estrogen on breast cancer development: Role of estrogen receptor independent mechanisms

14 July 2018

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BRCA1 and its toolbox for the maintenance of genome integrity

14 July 2018

1 reference

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Estrogen inhibits ATR signaling to cell cycle checkpoints and DNA repair

14 July 2018

1 reference

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Aromatase expression is increased in BRCA1 mutation carriers

14 July 2018

1 reference

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Clinical and pathologic characteristics of patients with BRCA-positive and BRCA-negative breast cancer.

14 July 2018

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The molecular etiology of breast cancer: evidence from biomarkers of risk

14 July 2018

1 reference

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Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer.

14 July 2018

1 reference

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Mechanism of translesion synthesis past an equine estrogen-DNA adduct by Y-family DNA polymerases

14 July 2018

1 reference

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Meta-analysis of BRCA1 and BRCA2 penetrance

14 July 2018

1 reference

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Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention

14 July 2018

1 reference

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Measuring fifteen endogenous estrogens simultaneously in human urine by high-performance liquid chromatography-mass spectrometry

14 July 2018

1 reference

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Modulation of aromatase expression by BRCA1: a possible link to tissue-specific tumor suppression.

14 July 2018

1 reference

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BRCA1 induces antioxidant gene expression and resistance to oxidative stress

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Translesion synthesis past equine estrogen-derived 2'-deoxycytidine DNA adducts by human DNA polymerases eta and kappa

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Extensive chromosomal breaks are induced by tamoxifen and estrogen in DNA repair-deficient cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Relative imbalances in estrogen metabolism and conjugation in breast tissue of women with carcinoma: potential biomarkers of susceptibility to cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Induction of uterine adenocarcinoma in CD-1 mice by catechol estrogens

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Carcinogenicity of catechol estrogens in Syrian hamsters

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Analysis of multiplex endogenous estrogen metabolites in human urine using ultra-fast liquid chromatography-tandem mass spectrometry: a case study for breast cancer.

14 July 2018

1 reference

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Excretion of estrogens, catecholestrogens and phytoestrogens in carriers of BRCA1 gene mutations: effects of metformin

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Increased chromosomal radiosensitivity in women carrying BRCA1/BRCA2 mutations assessed with the G2 assay.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Tissue estradiol is selectively elevated in receptor positive breast cancers while tumour estrone is reduced independent of receptor status.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Endocrine effects of adjuvant letrozole + triptorelin compared with tamoxifen + triptorelin in premenopausal patients with early breast cancer

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario, Canada

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Induction of A.T to G.C mutations by erroneous repair of depurinated DNA following estrogen treatment of the mammary gland of ACI rats.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Mutagenic activity of 4-hydroxyestradiol, but not 2-hydroxyestradiol, in BB rat2 embryonic cells, and the mutational spectrum of 4-hydroxyestradiol.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

The pattern of estradiol and progesterone differs in serum and tissue of benign and malignant ovarian tumors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Evidence that a burst of DNA depurination in SENCAR mouse skin induces error-prone repair and forms mutations in the H-ras gene

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Measurements of metaphase and interphase chromosome aberrations transmitted through early cell replication rounds in human lymphocytes exposed to low-LET protons and high-LET 12C ions

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024319

Pregnancy and risk of early breast cancer in carriers of BRCA1 and BRCA2

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24638981

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-13-2611

1 reference

28 July 2017

1 reference

28 July 2017

1 reference