Iron overload: molecular clues to its cause (Q33632933)

28 July 2017

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title

Iron overload: molecular clues to its cause (English)

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28 July 2017

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L C Kühn

1

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28 July 2017

publication date

1 May 1999

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28 July 2017

number of pages

3

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Trends in Biochemical Sciences

inferred from page(s)

published in

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28 July 2017

volume

24

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28 July 2017

issue

5

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28 July 2017

page(s)

164-166

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A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

28 July 2017

cites work

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7 January 2021

Hereditary hemochromatosis: effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells

1 reference

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7 January 2021

The hemochromatosis founder mutation in HLA-H disrupts beta2-microglobulin interaction and cell surface expression

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7 January 2021

Defective iron homeostasis in beta 2-microglobulin knockout mice recapitulates hereditary hemochromatosis in man.

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7 January 2021

beta2 knockout mice develop parenchymal iron overload: A putative role for class I genes of the major histocompatibility complex in iron metabolism

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7 January 2021

HFE gene knockout produces mouse model of hereditary hemochromatosis

1 reference

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7 January 2021

Immunohistochemistry of HLA-H, the protein defective in patients with hereditary hemochromatosis, reveals unique pattern of expression in gastrointestinal tract

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7 January 2021

Co-trafficking of HFE, a nonclassical major histocompatibility complex class I protein, with the transferrin receptor implies a role in intracellular iron regulation

1 reference

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7 January 2021

Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis

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7 January 2021

The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

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7 January 2021

Effect of pH and iron content of transferrin on its binding to reticulocyte receptors

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7 January 2021

pH and the recycling of transferrin during receptor-mediated endocytosis

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7 January 2021

Transferrin receptors in the human gastrointestinal tract. Relationship to body iron stores.

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7 January 2021

Transferrin receptor distribution and regulation in the rat small intestine. Effect of iron stores and erythropoiesis

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7 January 2021

Regulating the fate of mRNA: the control of cellular iron metabolism

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7 January 2021

Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

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7 January 2021

Duodenal ferritin synthesis in genetic hemochromatosis

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7 January 2021

Cloning and characterization of a mammalian proton-coupled metal-ion transporter

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7 January 2021

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7 January 2021

Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport.

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7 January 2021

Crystal structure of the hemochromatosis protein HFE and characterization of its interaction with transferrin receptor

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7 January 2021

10.1016/S0968-0004(99)01386-9

Identifiers

DOI

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28 July 2017

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