Structural modification of pantothenamides counteracts degradation by pantetheinase and improves antiplasmodial activity (Q33636093)

28 July 2017

title

Structural modification of pantothenamides counteracts degradation by pantetheinase and improves antiplasmodial activity (English)

1 reference

28 July 2017

Christina Spry

3

0 references

Marianne de Villiers

object named as

Marianne de Villiers

1

0 references

Erick Strauss

object named as

Erick Strauss

5

0 references

Kevin J. Saliba

object named as

Kevin J Saliba

6

0 references

author name string

Cristiano Macuamule

2

1 reference

28 July 2017

Yoo-Min Hyun

4

1 reference

28 July 2017

publication date

17 June 2013

1 reference

ACS Medicinal Chemistry Letters

28 July 2017

published in

1 reference

28 July 2017

volume

4

1 reference

28 July 2017

issue

8

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28 July 2017

page(s)

784-789

1 reference

Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated

28 July 2017

cites work

1 reference

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21 June 2018

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21 June 2018

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Diverse biological activities of the vascular non-inflammatory molecules - the Vanin pantetheinases

21 June 2018

1 reference

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Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum

21 June 2018

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Geminal dialkyl derivatives of N-substituted pantothenamides: synthesis and antibacterial activity

21 June 2018

1 reference

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Pantothenate utilization by Plasmodium as a target for antimalarial chemotherapy

21 June 2018

1 reference

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Inhibition of Plasmodium falciparum pH regulation by small molecule indole derivatives results in rapid parasite death

21 June 2018

1 reference

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A fluorescent assay suitable for inhibitor screening and vanin tissue quantification

21 June 2018

1 reference

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Development of a method for the parallel synthesis and purification of N-substituted pantothenamides, known inhibitors of coenzyme A biosynthesis and utilization

21 June 2018

1 reference

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Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli.

21 June 2018

1 reference

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A class of pantothenic acid analogs inhibits Plasmodium falciparum pantothenate kinase and represses the proliferation of malaria parasites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027574

Provitamin B5 (pantothenol) inhibits growth of the intraerythrocytic malaria parasite

21 June 2018

1 reference

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Inhibitors of pantothenate kinase: novel antibiotics for staphylococcal infections

21 June 2018

1 reference

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The antibiotic activity of N-pentylpantothenamide results from its conversion to ethyldethia-coenzyme a, a coenzyme a antimetabolite

21 June 2018

1 reference

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The nitrilase superfamily: classification, structure and function

21 June 2018

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Nutritional requirements of Plasmodium falciparum in culture. I. Exogenously supplied dialyzable components necessary for continuous growth

21 June 2018

1 reference

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Structure-activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors

21 June 2018

1 reference

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CJ-15,801, a fungal natural product, inhibits the intraerythrocytic stage of Plasmodium falciparum in vitro via an effect on pantothenic acid utilisation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027574

Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4027574

Assay of the enzymatic hydrolysis of pantetheine

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900746

12 December 2020

inferred from PubMed ID database lookup

N1-(substituted) pantothenamides, antimetabolites of pantothenic acid

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900746

12 December 2020

inferred from PubMed ID database lookup

Purification and properties of a pantetheine-hydrolyzing enzyme from pig kidney

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24900746

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1021/ML400180D

1 reference

release_x4jhg2zeczakrhj6ur2c7vkpz4

28 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/x4jhg2zeczakrhj6ur2c7vkpz4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4027574

1 reference

28 July 2017

1 reference